Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Joseph Bender"'
Autor:
Max J. Hilz, Nicole Lyn, Felix Marczykowski, Barbara Werner, Marc Pignot, Elvira Ponce, Joseph Bender, Michael Edigkaufer, Pronabesh DasMahapatra
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Background Fabry disease (FD), an X-linked lysosomal storage disorder, is caused by mutations in the gene encoding α-galactosidase A, resulting in lysosomal accumulation of globotriaosylceramide and other glycosphingolipids. Early detection
Externí odkaz:
https://doaj.org/article/1172e1b3428a47e5a3cf287d8baa6744
Autor:
Meagan L Hennessy, Nagaraju Indugu, Bonnie Vecchiarelli, Joseph Bender, Christa Pappalardo, Miranda Leibstein, John Toth, Ananya Katepalli, Satvik Garapati, Dipti Pitta
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0238882 (2020)
The development of a robust microbiome is critical to the health of dairy calves, but relatively little is known about the progression of the microbiome through the weaning transition. In this study, fecal samples were obtained from ten female Holste
Externí odkaz:
https://doaj.org/article/6b43e0ac3e324ac28f28523aa168cf79
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1007597 (2020)
As sequencing methodologies continue to advance, the availability of protein sequences far outpaces the ability of structure determination. Homology modeling is used to bridge this gap but relies on high-identity templates for accurate model building
Externí odkaz:
https://doaj.org/article/5cdfd0369e4e494280075a69c537194c
Autor:
Oanh Vu, Brian Joseph Bender, Lisa Pankewitz, Daniel Huster, Annette G. Beck-Sickinger, Jens Meiler
Publikováno v:
Molecules, Vol 27, Iss 210, p 210 (2022)
Molecules
Molecules
G protein-coupled receptors (GPCRs) represent the largest membrane protein family and a significant target class for therapeutics. Receptors from GPCRs’ largest class, class A, influence virtually every aspect of human physiology. About 45% of the
Autor:
Bonnie Vecchiarelli, Krum Nedelkov, Dipti Pitta, Meagan L. Hennessy, V.S. Kaplan-Shabtai, Joseph Bender, Nagaraju Indugu, S.E. Räisänen, Alexander N. Hristov, Joonpyo Oh, X. Chen, C.F. de Assis Lage, A. Melgar
Publikováno v:
JDS Communications. 2:329-333
Rumen microbes play an important role in the conversion of indigestible plant material to energy and protein in dairy cows. Sampling for ruminal contents via cannula is considered the gold standard technique for microbial analysis, but the technique
Autor:
Nagaraju Indugu, Christa Pappalardo, John D. Toth, Miranda Leibstein, Darko Stefanovski, Ananya Katepalli, Joseph Bender, Bonnie Vecchiarelli, Dipti Pitta, Meagan L. Hennessy, Laurel E. Redding, Satvik Garapati
Publikováno v:
Journal of Dairy Science. 104:7225-7232
Diarrhea is a major cause of illness and death in preweaned calves and causes significant economic losses to producers. A better understanding of the fecal microbiota in diarrheic and nondiarrheic calves could lead to improved treatment and preventio
Autor:
Nicholas N. Nissen, Michael J. Pishvaian, R Joseph Bender, Simon S. Lo, Emanuel F. Petricoin, Jaimie Koo, Jonathan R. Brody, Richard Tuli
Publikováno v:
JCO precision oncology. 1
Autor:
Susanna Elisabeth Räisänen, Bonnie Vecchiarelli, Meagan L. Hennessy, Alexander N. Hristov, M. E. Fetter, Krum Nedelkov, Addison Spitzer, Nagaraju Indugu, Dipti Pitta, Andrea Fernandez, Darko Stefanovski, Joseph Bender, Veronica Kaplan-Shabtai, A. Melgar, C.F.A. Lage
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology, Vol 12 (2021)
Microbial syntrophy (obligate metabolic mutualism) is the hallmark of energy-constrained anaerobic microbial ecosystems. For example, methanogenic archaea and fermenting bacteria coexist by interspecies hydrogen transfer in the complex microbial ecos
Autor:
Davendra Sohal, Bradley J. Monk, R Joseph Bender, Michael J. Pishvaian, Patricia DeArbeloa, Kathleen N. Moore, Robert L. Coleman, Shruti Rao, David D Halverson, Andrew Eugene Hendifar, Thomas J. Herzog, Subha Madhavan, Paula R. Pohlmann, Emanuel F. Petricoin, Edik M. Blais, Vincent Chung, Sam Mikhail, Kai He, Simina M. Boca
Publikováno v:
JAMIA Open
JAMIA open, vol 2, iss 4
JAMIA open, vol 2, iss 4
Objectives Scalable informatics solutions that provide molecularly tailored treatment recommendations to clinicians are needed to streamline precision oncology in care settings. Materials and Methods We developed a cloud-based virtual molecular tumor
Autor:
Gary Gregory, Veronica Placencio-Hickok, Edik M. Blais, Joseph Bender, Michael J. Pishvaian, Jun Gong, Andrew Eugene Hendifar, Michelle Guan, Emanuel F. Petricoin, Richard Tuli
Publikováno v:
Oncotarget
Oncotarget, vol 10, iss 58
Oncotarget, vol 10, iss 58
Background Multi-omic profiling of pancreatic neuroendocrine tumors (PanNETs) was performed to correlate genomic, proteomic, and molecular pathway alterations with clinicopathologic factors and identify novel co-occurring pathogenic alterations of po