Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Joseph Bazzill"'
Autor:
Chitra Subramanian, Patrick T. Grogan, Ton Wang, Joseph Bazzill, Ang Zuo, Peter T. White, Avinaash Kalidindi, Dawn Kuszynski, Grace Wang, Brian S. J. Blagg, Mark S. Cohen
Publikováno v:
Molecular Oncology, Vol 14, Iss 9, Pp 2058-2068 (2020)
In patients with triple‐negative breast cancer (TNBC), evidence suggests that tumor‐initiating cells (TIC) have stem cell‐like properties, leading to invasion and metastasis. HSP90 plays a critical role in the conformational maintenance of many
Externí odkaz:
https://doaj.org/article/b903ea765283488cbf81ea52f406e330
Autor:
Jennifer Speth, Loka R. Penke, Joseph Bazzill, Douglas A. Arenberg, James J. Moon, Venkateshwar G. Keshamouni, Vibha N. Lama, Marc Peters-Golden
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 36-36 (2018)
OBJECTIVES/SPECIFIC AIMS: Insufficient endogenous expression of suppressor of cytokine signaling 3 (SOCS3) with subsequent over-activation of its target, the transcription factor STAT3, has been associated with tumorigenesis and cancer development in
Externí odkaz:
https://doaj.org/article/15405acec5eb411da761d139c5734010
Autor:
Lukasz J. Ochyl, Janet L. Smith, Celia C. LaBranche, Kyung Soo Park, Jennifer L. Meagher, Sejin Son, Jie Xu, David C. Montefiori, Jun Song, Jutaek Nam, Seung Won Shin, James J. Moon, Joseph Bazzill, Jeanne A. Stuckey, Louise Chang
Publikováno v:
Journal of Controlled Release
The current health crisis of corona virus disease 2019 (COVID-19) highlights the urgent need for vaccine systems that can generate potent and protective immune responses. Protein vaccines are safe, but conventional approaches for protein-based vaccin
Autor:
James J. Moon, Zbigniew Zaslona, Joseph Bazzill, Loka R. Penke, Yvonne J. Huang, Christina Draijer, Marc Peters-Golden, Njira L Lugogo, Jennifer M. Speth
Publikováno v:
FASEB J
Resident alveolar macrophages (AMs) suppress allergic inflammation in murine asthma models. Previously we reported that resident AMs can blunt inflammatory signaling in alveolar epithelial cells (ECs) by transcellular delivery of suppressor of cytoki
Autor:
Christopher L. Cooper, Laura C. Kalinyak, Sabrina M. Stronsky, Joseph Bazzill, Jesse T. Steffens, James J. Moon, Lukasz J. Ochyl, Sean A. Van Tongeren
Publikováno v:
Nanomedicine
The recent outbreaks of Ebolavirus (EBOV) in West Africa underscore the urgent need to develop an effective EBOV vaccine. Here, we report the development of synthetic nanoparticles as a safe and highly immunogenic platform for vaccination against EBO
Publikováno v:
Nano Letters. 18:7832-7838
Elicitation of neutralizing antibody responses against hepatitis C virus (HCV) has been a challenging goal. While the E2 subunit of the HCV envelope glycoprotein complex is a promising target for generating cross-genotype neutralizing antibodies, vac
Autor:
Marc Peters-Golden, Zbigniew Zaslona, Christina Draijer, Jennifer M. Speth, Loka R. Penke, Joseph Bazzill, James J. Moon
Publikováno v:
A31. ASTHMA TRANSLATIONAL STUDIES.
Autor:
Vibha N. Lama, Kyung Soo Park, Rachel L. Zemans, Rafael Gil de Rubio, Daniel J. Schneider, James J. Moon, Jennifer M. Speth, Venkateshwar G. Keshamouni, Douglas A. Arenberg, Marc Peters-Golden, Hideyasu Ouchi, Loka R. Penke, Joseph Bazzill
Publikováno v:
JCI Insight. 4
Lung cancer remains the leading cause of cancer-related death in the United States. Although the alveolar macrophage (AM) comprises the major resident immune cell in the lung, few studies have investigated its role in lung cancer development. We rece
Publikováno v:
Nanomedicine. 12:673-682
The development of a successful vaccine against HIV is a major global challenge. Antiretroviral therapy is the standard treatment against HIV-1 infection. However, only 46% of the eligible people received the therapy in 2015. Furthermore, suboptimal
Publikováno v:
C63. MECHANISTIC STUDIES IN COPD.