Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Joseph Bartho"'
Autor:
Stephan Woike, Sebastian Eustermann, James Jung, Simon Josef Wenzl, Götz Hagemann, Joseph Bartho, Katja Lammens, Agata Butryn, Franz Herzog, Karl-Peter Hopfner
Publikováno v:
Nature Structural & Molecular Biology. 30:640-649
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5b3e538c86d3bb16fd0df531d950b62
https://doi.org/10.1038/s41594-023-00966-0
https://doi.org/10.1038/s41594-023-00966-0
Autor:
U Pehl, M. Rotheneder, T Fuchß, K. Stakyte, Joseph Bartho, Karl-Peter Hopfner, E van de Logt, Ulrich Grädler, Aaron Alt, Katja Lammens
Publikováno v:
Nature Structural & Molecular Biology. 28:789-798
Human checkpoint kinase ataxia telangiectasia-mutated (ATM) plays a key role in initiation of the DNA damage response following DNA double-strand breaks. ATM inhibition is a promising approach in cancer therapy, but, so far, detailed insights into th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06949eb7c6231fd9627c93a70ad14206
https://doi.org/10.1038/s41594-021-00654-x
https://doi.org/10.1038/s41594-021-00654-x
Autor:
Karl-Peter Hopfner, Joseph Bartho, Katja Lammens, Jasmin Kleinschwärzer, David Jan Drexler, Adrian M. Bandera, Gregor Witte
Publikováno v:
Nucleic Acids Research
Nucleic acids research 49(17), 10166-10177 (2021). doi:10.1093/nar/gkab736
Nucleic acids research 49(17), 10166-10177 (2021). doi:10.1093/nar/gkab736
Nucleic acids research / Special publication 49(17), 10166 - 10177 (2021). doi:10.1093/nar/gkab736
The cyclic dinucleotide second messenger c-di-AMP is a major player in regulation of potassium homeostasis and osmolyte transport in a variety of
The cyclic dinucleotide second messenger c-di-AMP is a major player in regulation of potassium homeostasis and osmolyte transport in a variety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6400824bf1df0b4c35e5acfa54a594e
https://doi.org/10.1093/nar/gkab736
https://doi.org/10.1093/nar/gkab736
Autor:
Joseph Bartho, Che A. Stafford, Veit Hornung, Carina C. de Oliveira Mann, Karl-Peter Hopfner, Katja Lammens, Gregor Witte, Sebastian Michalski
Publikováno v:
Nature. 587:678-682
Cyclic GMP–AMP synthase (cGAS) is an innate immune sensor for cytosolic microbial DNA1. After binding DNA, cGAS synthesizes the messenger 2′3′-cyclic GMP–AMP (cGAMP)2–4, which triggers cell-autonomous defence and the production of type I in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4902062e3f2d92dd92db78402c6ed28
https://doi.org/10.1038/s41586-020-2748-0
https://doi.org/10.1038/s41586-020-2748-0
Autor:
Joseph Bartho, Karl-Peter Hopfner, Jan-Hinnerk Saathoff, Brigitte Kessler, Aaron Alt, Fabian Gut, Katja Lammens, Lisa Käshammer
Publikováno v:
Molecular Cell. 76:382-394.e6
Summary DNA double-strand breaks (DSBs) threaten genome stability throughout life and are linked to tumorigenesis in humans. To initiate DSB repair by end joining or homologous recombination, the Mre11-nuclease Rad50-ATPase complex detects and proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc02b128b28ff0f86edabc3b5e6fbd2
https://doi.org/10.1016/j.molcel.2019.07.035
https://doi.org/10.1016/j.molcel.2019.07.035