Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Joseph BO"'
Autor:
Godfred Kiteinkwa Laar, Justine Mwinbeku, Ebenezer Allotey Pappoe, Emmanuella Obike, Elizabeth Ankomah, Belinda Baidoo, Diana Baaba Morrison, Joseph Boachie, Patrick Adu
Publikováno v:
Archives of Public Health, Vol 82, Iss 1, Pp 1-14 (2024)
Abstract Background Sickle cell disease (SCD) is a common monogenic inheritable condition in sub-Saharan Africa. 30% of Ghanaians are estimated to be carriers creating a condition for stable SCD penetrance. Being inheritable, SCD is scientifically pr
Externí odkaz:
https://doaj.org/article/3e231e3b22e54e4eb8b2e95be4bcb95d
Autor:
Agnes Cheong, Florin Craciun, Hervé Husson, Joseph Gans, Javier Escobedo, Yi-Chien Chang, Lilu Guo, Mariana Goncalves, Nathan Kaplan, Laurie A. Smith, Sarah Moreno, Joseph Boulanger, Shiguang Liu, Jacqueline Saleh, Mindy Zhang, Anna S. Blazier, Weiliang Qiu, Andrew Macklin, Tejaswi Iyyanki, Clément Chatelain, Shameer Khader, Thomas A. Natoli, Oxana Ibraghimov-Beskrovnaya, Dimitry Ofengeim, Jonathan D. Proto
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract While significant advances have been made in understanding renal pathophysiology, less is known about the role of glycosphingolipid (GSL) metabolism in driving organ dysfunction. Here, we used a small molecule inhibitor of glucosylceramide s
Externí odkaz:
https://doaj.org/article/68828197b6744988a8444a603fea8bde
Autor:
Josef Borg, Conor Loy, JangKeun Kim, Alfred Buhagiar, Christopher Chin, Namita Damle, Iwijn De Vlaminck, Alex Felice, Tammy Liu, Irina Matei, Cem Meydan, Masafumi Muratani, Omary Mzava, Eliah Overbey, Krista A. Ryon, Scott M. Smith, Braden T. Tierney, Guy Trudel, Sara R. Zwart, Afshin Beheshti, Christopher E. Mason, Joseph Borg
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract It is now widely recognised that the environment in space activates a diverse set of genes involved in regulating fundamental cellular pathways. This includes the activation of genes associated with blood homeostasis and erythropoiesis, with
Externí odkaz:
https://doaj.org/article/0b66a7ae76394b36a7d5a9bcfb0634e7
Autor:
Allen Seylani, Aman Singh Galsinh, Alexia Tasoula, Anu R I, Andrea Camera, Jean Calleja-Agius, Joseph Borg, Chirag Goel, JangKeun Kim, Kevin B. Clark, Saswati Das, Shehbeel Arif, Michael Boerrigter, Caroline Coffey, Nathaniel Szewczyk, Christopher E. Mason, Maria Manoli, Fathi Karouia, Hansjörg Schwertz, Afshin Beheshti, Dana Tulodziecki
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Mounting ambitions and capabilities for public and private, non-government sector crewed space exploration bring with them an increasingly diverse set of space travelers, raising new and nontrivial ethical, legal, and medical policy and prac
Externí odkaz:
https://doaj.org/article/e2582b59e7f34a628a4a2b8ff369392b
Autor:
Begum Aydogan Mathyk, Marshall Tabetah, Rashid Karim, Victoria Zaksas, JangKeun Kim, R. I. Anu, Masafumi Muratani, Alexia Tasoula, Ruth Subhash Singh, Yen-Kai Chen, Eliah Overbey, Jiwoon Park, Henry Cope, Hossein Fazelinia, Davide Povero, Joseph Borg, Remi V. Klotz, Min Yu, Steven L. Young, Christopher E. Mason, Nathaniel Szewczyk, Riley M. St Clair, Fathi Karouia, Afshin Beheshti
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Organismal adaptations to spaceflight have been characterized at the molecular level in model organisms, including Drosophila and C. elegans. Here, we extend molecular work to energy metabolism and sex hormone signaling in mice and humans. W
Externí odkaz:
https://doaj.org/article/d61840f0a1224eb1838b2490772d979a
Autor:
Laura K. Harward, René M. Lento, Andrew Teer, Stephanie Samph, Megan E. Parmenter, Joseph Bonvie, Charlotte Magee, Lauren Brenner, Kaitlin Picard, Wesley Sanders, William Joseph Tinney, Cyrielle Andrew, Jessica Covitz, Katrina Echevarria, Ryan Vanderweit, Nicolette S. Maggiolo, Kaloyan S. Tanev
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
The two-week Home Base Intensive Clinical Program (ICP) provides treatment to veterans and active duty service members suffering from primary diagnoses of posttraumatic stress disorder (PTSD), traumatic brain injury (TBI), anxiety, or depression. Fir
Externí odkaz:
https://doaj.org/article/d9b242a5a06c4d0eb1fada431136da96
Autor:
Lucas Del Mouro, Rudy Lerosey-Aubril, Joseph Botting, Robert Coleman, Robert R. Gaines, Jacob Skabelund, James C. Weaver, Javier Ortega-Hernández
Publikováno v:
Royal Society Open Science, Vol 11, Iss 9 (2024)
Modern poriferans are classified into four classes—Calcarea, Demospongiae, Hexactinellida and Homoscleromorpha—the recognition of which in fossil specimens almost exclusively relies on spicule morphology and arrangement. Early fossil representati
Externí odkaz:
https://doaj.org/article/911086e5a916483fb24bdfd502345d09
Autor:
Percina Machava, Winete Joaquim, Joseph Borrell, Shannon Richardson, Uneisse Cassia, Muhammad Sidat, Alice Maieca, Cláudia Massitela, Yara Quelhas, Cafrina Mucuila, Beatriz Elias, Massada da Rocha, H. Simon Schaaf, W. Chris Buck
Publikováno v:
AIDS Research and Therapy, Vol 21, Iss 1, Pp 1-7 (2024)
Abstract Background Bacillus Calmette-Guérin (BCG) reactions are the most common cause of immune reconstitution inflammatory syndrome (IRIS) in HIV-positive infants who initiate antiretroviral therapy (ART). There is limited evidence regarding the i
Externí odkaz:
https://doaj.org/article/011e12c05547455fbc474d071c8ac032
Publikováno v:
Cogent Social Sciences, Vol 10, Iss 1 (2024)
AbstractIn Ghana, terrestrial sand mining in rural and peri-urban areas negatively affects the livelihoods of the majority of the residents employed in land-based livelihoods. We examine the sustainability of the alternative livelihood strategies the
Externí odkaz:
https://doaj.org/article/7f9da373d31c47788cb0ce5f94efe551
Autor:
Jason Deng, Svetlana Belyanskaya, Ninad Prabhu, Christopher Arico-Muendel, Hongfeng Deng, Christopher B. Phelps, David I. Israel, Hongfang Yang, Joseph Boyer, G. Joseph Franklin, Jeremy L. Yap, Kenneth E. Lind, Ching-Hsuan Tsai, Christine Donahue, Jennifer D. Summerfield
Publikováno v:
SLAS Discovery, Vol 29, Iss 5, Pp 100171- (2024)
DNA-encoded small molecule library technology has recently emerged as a new paradigm for identifying ligands against drug targets. To date, it has been used to identify ligands against targets that are soluble or overexpressed on cell surfaces. Here,
Externí odkaz:
https://doaj.org/article/200cb0758edc446ea0423cf022c88bf1