Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Joseph B, Monahan"'
Autor:
Douglas V. Faget, Xianmin Luo, Matthew J. Inkman, Qihao Ren, Xinming Su, Kai Ding, Michael R. Waters, Ganesh Kumar Raut, Gaurav Pandey, Paarth B. Dodhiawala, Renata Ramalho-Oliveira, Jiayu Ye, Thomas Cole, Bhavna Murali, Alexander Zheleznyak, Monica Shokeen, Kurt R. Weiss, Joseph B. Monahan, Carl J. DeSelm, Adrian V. Lee, Steffi Oesterreich, Katherine N. Weilbaecher, Jin Zhang, David G. DeNardo, Sheila A. Stewart
Publikováno v:
Journal of Bone Oncology, Vol 45, Iss , Pp 100534- (2024)
Externí odkaz:
https://doaj.org/article/68141490621946f3a9066df6df8be2eb
Autor:
David Gordon, Alan Kivitz, Atul Singhal, David Burt, Madison C. Bangs, Emma E. Huff, Heidi Rath Hope, Joseph B. Monahan
Publikováno v:
ACR Open Rheumatology, Vol 5, Iss 2, Pp 63-70 (2023)
Objective The study objective was to evaluate the safety, tolerability, pharmacodynamics, and preliminary efficacy of ATI‐450 with methotrexate in patients with rheumatoid arthritis (RA). Methods A parallel‐assignment, placebo‐controlled, inves
Externí odkaz:
https://doaj.org/article/9707f56a9a9e46caa023363d9f8c3e21
Autor:
Douglas V. Faget, Xianmin Luo, Matthew J. Inkman, Qihao Ren, Xinming Su, Kai Ding, Michael R. Waters, Ganesh Kumar Raut, Gaurav Pandey, Paarth B. Dodhiawala, Renata Ramalho-Oliveira, Jiayu Ye, Thomas Cole, Bhavna Murali, Alexander Zheleznyak, Monica Shokeen, Kurt R. Weiss, Joseph B. Monahan, Carl J. DeSelm, Adrian V. Lee, Steffi Oesterreich, Katherine N. Weilbaecher, Jin Zhang, David G. DeNardo, Sheila A. Stewart
Publikováno v:
Cancer Discovery. :OF1-OF24
Metastatic breast cancer is an intractable disease that responds poorly to immunotherapy. We show that p38MAPKα inhibition (p38i) limits tumor growth by reprogramming the metastatic tumor microenvironment in a CD4+ T cell-, IFNγ-, and macrophage-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c99f40122f5e1ab8ee6b87545b7dea6
https://doi.org/10.1158/2159-8290.cd-22-0907
https://doi.org/10.1158/2159-8290.cd-22-0907
Autor:
Jianqiu Xiao, Chun Wang, Juo-Chin Yao, Yael Alippe, Tong Yang, Dustin Kress, Kai Sun, Kourtney L Kostecki, Joseph B Monahan, Deborah J Veis, Yousef Abu-Amer, Daniel C Link, Gabriel Mbalaviele
Publikováno v:
PLoS Biology, Vol 18, Iss 8, p e3000807 (2020)
Radiotherapy is a commonly used conditioning regimen for bone marrow transplantation (BMT). Cytotoxicity limits the use of this life-saving therapy, but the underlying mechanisms remain poorly defined. Here, we use the syngeneic mouse BMT model to te
Externí odkaz:
https://doaj.org/article/dfcc01b5a9e84be9b30dca2343479fa0
Autor:
Heidi R. Hope, Susan Hockerman, Matt Saabye, Loreen Stillwell, Rakesh Basavalingappa, Catherine Emanual, Steve Mnich, Madison Bangs, Emma Huff, Aparna Kaul, Anne Hildebrand, Marco Cardillo, Ajay Aggarwal, Joseph B. Monahan
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c62b558510ebdeea0073ddc1a1f8fda1
https://doi.org/10.1124/jpet.122.541040
https://doi.org/10.1124/jpet.122.541040
Autor:
Sheila A. Stewart, David G. DeNardo, Jin Zhang, Katherine N. Weilbaecher, Steffi Oesterreich, Adrian V. Lee, Carl J. DeSelm, Joseph B. Monahan, Kurt R. Weiss, Monica Shokeen, Alexander Zheleznyak, Bhavna Murali, Thomas Cole, Jiayu Ye, Renata Ramalho-Oliveira, Paarth B. Dodhiawala, Gaurav Pandey, Ganesh Kumar Raut, Michael R. Waters, Kai Ding, Xinming Su, Qihao Ren, Matthew J. Inkman, Xianmin Luo, Douglas V. Faget
Metastatic breast cancer is an intractable disease that responds poorly to immunotherapy. We show that p38MAPKα inhibition (p38i) limits tumor growth by reprogramming the metastatic tumor microenvironment in a CD4+ T cell-, IFNγ-, and macrophage-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b9eae3188444c1328aa596613891f1
https://doi.org/10.1158/2159-8290.c.6626595
https://doi.org/10.1158/2159-8290.c.6626595
Autor:
Sheila A. Stewart, David G. DeNardo, Jin Zhang, Katherine N. Weilbaecher, Steffi Oesterreich, Adrian V. Lee, Carl J. DeSelm, Joseph B. Monahan, Kurt R. Weiss, Monica Shokeen, Alexander Zheleznyak, Bhavna Murali, Thomas Cole, Jiayu Ye, Renata Ramalho-Oliveira, Paarth B. Dodhiawala, Gaurav Pandey, Ganesh Kumar Raut, Michael R. Waters, Kai Ding, Xinming Su, Qihao Ren, Matthew J. Inkman, Xianmin Luo, Douglas V. Faget
Contains supplemental figures and legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451aa53a298632b8473ee1def8a44610
https://doi.org/10.1158/2159-8290.22732263.v1
https://doi.org/10.1158/2159-8290.22732263.v1
Autor:
Sheila A. Stewart, David G. DeNardo, Jin Zhang, Katherine N. Weilbaecher, Steffi Oesterreich, Adrian V. Lee, Carl J. DeSelm, Joseph B. Monahan, Kurt R. Weiss, Monica Shokeen, Alexander Zheleznyak, Bhavna Murali, Thomas Cole, Jiayu Ye, Renata Ramalho-Oliveira, Paarth B. Dodhiawala, Gaurav Pandey, Ganesh Kumar Raut, Michael R. Waters, Kai Ding, Xinming Su, Qihao Ren, Matthew J. Inkman, Xianmin Luo, Douglas V. Faget
Table containing all of our reagents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d941d5264bedfea5002db1e9ebc25a
https://doi.org/10.1158/2159-8290.22732260
https://doi.org/10.1158/2159-8290.22732260
Autor:
Sheila A. Stewart, Joseph B. Monahan, Gabriel Mbalaviele, Morag Park, Katherine N. Weilbaecher, Barry Burnette, Michael H. Ross, Xinming Su, Elise Alspach, Kathleen Leahy, Yujie Fu, Kevin C. Flanagan, Tina Gruosso, Radia Marie Johnson, Chun Wang, Douglas V. Faget, Xianmin Luo, Qihao Ren, Bhavna Murali
Supplementary Data from Inhibition of the Stromal p38MAPK/MK2 Pathway Limits Breast Cancer Metastases and Chemotherapy-Induced Bone Loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae5429acbe1ebc17d73d2fe9b51e854
https://doi.org/10.1158/0008-5472.22419464.v1
https://doi.org/10.1158/0008-5472.22419464.v1
Publikováno v:
Clinical Pharmacology : Advances and Applications
David Gordon,1 Edward T Hellriegel,1 Heidi Rath Hope,2 David Burt,1 Joseph B Monahan2 1Research and Development, Aclaris Therapeutics, Inc., Wayne, PA, USA; 2Research and Development, Aclaris Therapeutics, Inc., and Confluence Discovery Technologies,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f99e69e6e52c1669292ef34fd7d167
http://europepmc.org/articles/PMC8203602
http://europepmc.org/articles/PMC8203602