Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Joseph Antonios"'
Autor:
Richard G. Everson, Willy Hugo, Lu Sun, Joseph Antonios, Alexander Lee, Lizhong Ding, Melissa Bu, Sara Khattab, Carolina Chavez, Emma Billingslea-Yoon, Andres Salazar, Benjamin M. Ellingson, Timothy F. Cloughesy, Linda M. Liau, Robert M. Prins
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract In this randomized phase II clinical trial, we evaluated the effectiveness of adding the TLR agonists, poly-ICLC or resiquimod, to autologous tumor lysate-pulsed dendritic cell (ATL-DC) vaccination in patients with newly-diagnosed or recurre
Externí odkaz:
https://doaj.org/article/3d3f4ce1e0b340f7b0779a6e1bdebc9c
Autor:
Richard G. Everson, Willy Hugo, Lu Sun, Joseph Antonios, Alexander Lee, Lizhong Ding, Melissa Bu, Sara Khattab, Carolina Chavez, Emma Billingslea-Yoon, Andres Salazar, Benjamin M. Ellingson, Timothy F. Cloughesy, Linda M. Liau, Robert M. Prins
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/e393bc4c03db441e95498e95bf6c4910
Autor:
Robert M. Prins, Christel Herold-Mende, Linda M. Liau, Timothy F. Cloughesy, William H. Yong, Richard Everson, Anthony Wang, David Nathanson, Nicholas Bayless, Nikesh Kotecha, Alejandro Garcia, Joseph Antonios, Aaron Mochizuki, Mildred Galvez, Carmen Rapp, Saskia Roesch, Max Mastall, Janet Treger, Joey Orpilla, Shaina Sedighim, Melody Hsu, Alexander Lee, Tom B. Davidson
Supplementary Figure 3: Gene expression analysis shows increased transcription of activation and exhaustion genes in the PD-1+ population in glioma TILs and of antigen experienced genes in the PD-1+ population in glioma PBMCs (each dot represents a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dde78b81dc465a1fa300e2da7231211
https://doi.org/10.1158/1078-0432.22471280
https://doi.org/10.1158/1078-0432.22471280
Autor:
Robert M. Prins, Christel Herold-Mende, Linda M. Liau, Timothy F. Cloughesy, William H. Yong, Richard Everson, Anthony Wang, David Nathanson, Nicholas Bayless, Nikesh Kotecha, Alejandro Garcia, Joseph Antonios, Aaron Mochizuki, Mildred Galvez, Carmen Rapp, Saskia Roesch, Max Mastall, Janet Treger, Joey Orpilla, Shaina Sedighim, Melody Hsu, Alexander Lee, Tom B. Davidson
Supplementary Table 1: Panel of CyTOF markers used in our study and how each marker was classified.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a859c349ad7a82a703bad70e55bb2d1
https://doi.org/10.1158/1078-0432.22471277.v1
https://doi.org/10.1158/1078-0432.22471277.v1
Autor:
Robert M. Prins, Christel Herold-Mende, Linda M. Liau, Timothy F. Cloughesy, William H. Yong, Richard Everson, Anthony Wang, David Nathanson, Nicholas Bayless, Nikesh Kotecha, Alejandro Garcia, Joseph Antonios, Aaron Mochizuki, Mildred Galvez, Carmen Rapp, Saskia Roesch, Max Mastall, Janet Treger, Joey Orpilla, Shaina Sedighim, Melody Hsu, Alexander Lee, Tom B. Davidson
Purpose:Glioblastoma (GBM) is the most common primary malignant tumor in the central nervous system. Our recent preclinical work has suggested that PD-1/PD-L1 plays an important immunoregulatory role to limit effective antitumor T-cell responses indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b405b9d3ab6a83cb2eb931617679f7
https://doi.org/10.1158/1078-0432.c.6527837.v1
https://doi.org/10.1158/1078-0432.c.6527837.v1
Autor:
Robert M. Prins, Christel Herold-Mende, Linda M. Liau, Timothy F. Cloughesy, William H. Yong, Richard Everson, Anthony Wang, David Nathanson, Nicholas Bayless, Nikesh Kotecha, Alejandro Garcia, Joseph Antonios, Aaron Mochizuki, Mildred Galvez, Carmen Rapp, Saskia Roesch, Max Mastall, Janet Treger, Joey Orpilla, Shaina Sedighim, Melody Hsu, Alexander Lee, Tom B. Davidson
Supplementary Figure 1: T cells from GBM patient TILs show highest expression of PD-1 compared to healthy donor PBMC and GBM patient PBMCs A) A representative flow cytometry plot measuring PD-1+ expression on CD4+ and CD8+ T cells from Healthy Donor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a71858d7ce51fa1fc8f4761b150acac
https://doi.org/10.1158/1078-0432.22471286
https://doi.org/10.1158/1078-0432.22471286
Autor:
Robert M. Prins, Christel Herold-Mende, Linda M. Liau, Timothy F. Cloughesy, William H. Yong, Richard Everson, Anthony Wang, David Nathanson, Nicholas Bayless, Nikesh Kotecha, Alejandro Garcia, Joseph Antonios, Aaron Mochizuki, Mildred Galvez, Carmen Rapp, Saskia Roesch, Max Mastall, Janet Treger, Joey Orpilla, Shaina Sedighim, Melody Hsu, Alexander Lee, Tom B. Davidson
Supplementary Figure 2: Additional CyTOF data A) The percentage of the CD3+ PD-1+ cells from the TIL (green dots) and PBMCs (red dots) in each cluster (*P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f7bb31ecfe60aeeeaa6a83c799334a
https://doi.org/10.1158/1078-0432.22471283
https://doi.org/10.1158/1078-0432.22471283
Autor:
Daniela Renedo, Nanthiya Sujijantarat, Joseph Antonios, Andrew Koo, Julian Acosta, Guido J Falcone, Ryan Hebert, Lauren H Sansing, Dhasakumar S Navaratnam, Charles Matouk
Publikováno v:
Stroke. 54
Background: Mechanical thrombectomy (MT) has significantly improved clinical outcomes in acute ischemic stroke. We used single-cell RNA sequencing (scRNA-seq) to describe the landscape of human clots at single cell resolution seeking to provide great
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee0238c61d32a71fdc4a90e07823670f
https://doi.org/10.1161/str.54.suppl_1.15
https://doi.org/10.1161/str.54.suppl_1.15
Autor:
Nanthiya Sujijantarat, Andrew Koo, Ivan Jambor, Ajay Malhotra, Anna Crawford, Mercy Mazurek, Nethra Parasuram, Vineetha Yadlapalli, Isha R Chavva, Joseph Antonios, Aladine Elsamadicy, Daniela Renedo, Ryan Hebert, Joseph L Schindler, Lauren H Sansing, Adam H De Havenon, Madelynne Olexa, Juan E Iglesias, Matthew Rosen, W Taylor T Kimberly, Nils H Petersen, Kevin N Sheth, Charles Matouk
Publikováno v:
Stroke. 54
Introduction: Conventional MRI (cMRI) is not routinely available post-mechanical thrombectomy (MT), which can preclude accurate infarction assessment. Our objective was to evaluate the use of low-field portable MRI (pMRI) for bedside evaluation post-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2de7b738f686e19fc12b0f79da48449b
https://doi.org/10.1161/str.54.suppl_1.wp154
https://doi.org/10.1161/str.54.suppl_1.wp154
Autor:
Declan McGuone, Shaurey Vetsa, Bulent Omay, Joseph Antonios, Danielle F Miyagishima, Zeynep Erson Omay, Jennifer Moliterno, Tanyeri Barak, Elena I Fomchenko, Evan Gorelick, Sagar Vasandani, Nathan Lifton, Nicholas Blondin, Lan Jin, Amy Y Zhao, Kanat Yalcin, Arushii Nadar, Trisha P Gupte, Neelan Marianayagam, Anita Huttner, Brianna Carusillo Theriault, Zachary Corbin, Robert K. Fulbright
Publikováno v:
Journal of Neuro-Oncology
Objective While adjuvant treatment regimens have been modified for older patients with glioblastoma (GBM), surgical strategies have not been tailored. Methods Clinical data of 48 consecutive patients aged 70 years or older, who underwent surgical res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f56ff85b6e90beb5dbc2fd7a37b125a
https://doi.org/10.1007/s11060-021-03862-z
https://doi.org/10.1007/s11060-021-03862-z