Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Joseph Anthony D'alessio"'
Autor:
Tomas Rejtar, Markus Vogel, Srinivas Chakravarthy, Joseph Anthony D'alessio, Katie Russo, Alyssa Grantham, David A. Ruddy, Sabine Deutsch, Si-Qi Liu, Katherine Seiss, Tiancen Hu, William R. Tschantz, Glenn Dranoff, Casey Landry, Rajiv Chopra, Joel Wagner, Brian Granda, Kimberly Aardalen
Publikováno v:
Cancer Immunol Res
CD3-bispecific antibodies represent an important therapeutic strategy in oncology. These molecules work by redirecting cytotoxic T cells to antigen-bearing tumor cells. Although CD3-bispecific antibodies have been developed for several clinical indic
Autor:
Dominik Pistorius, Kathrin Buntin, Eric Weber, Etienne Richard, Caroline Bouquet, Séverine Wollbrett, Hugo Regenass, Victor Peón, Marcel Böhm, Régis Kessler, Thomas Gempeler, Anne Haberkorn, Laurin Wimmer, Christian Lanshoeft, John Davis, Dominik Hainzl, Joseph Anthony D'Alessio, Eusebio Manchado, Frank Petersen
Publikováno v:
Chemistry – A European Journal. 28
Access to the cyclic depsipeptide FR900359 (FR), a selective G
Autor:
Chi Ying, Jane Gu, Yan Tang, Suzanna Clark, Ursula Jeffry, Kathy Miller, Rick Newcombe, Qing Sheng, Christopher Karim, GiNell Elliot, Tinya Abrams, Thomas Huber, Jason Damiano, Katherine Rendahl, Paul Kwon, Angela Tam, Nancy Pryer, Majid Ghoddusi, Daniel Menezes, William R. Tschantz, Margaret E. McLaughlin, Emma Lees, Christie Fanton, Jean-Michel Rondeau, S. Lehmann, Anu Connor, Judith A. Abraham, Joseph Anthony D'alessio, Felipe Correa Geyer, Keith Mansfield
Publikováno v:
Molecular cancer therapeutics. 20(7)
The cell surface glycoprotein P-cadherin is highly expressed in a number of malignancies, including those arising in the epithelium of the bladder, breast, esophagus, lung, and upper aerodigestive system. PCA062 is a P-cadherin specific antibody–dr
Autor:
Marion Lacaud, Tinya Abrams, Piotr Martyniuk, Suzanna Clark, William Mallet, Daniel S. Palacios, Erik Meredith, Cristina Nieto-Oberhuber, Joseph Anthony D'alessio, Mauro Zurini, Grazia Piizzi, Francesca Perruccio, Morvarid Mohseni, Darryl Brynley Jones, Michael Patrick Dillon, Carl Uli Bialucha, Alexei S. Karpov, Thomas G. Gesner, Ankita Raikar
Publikováno v:
ACS Medicinal Chemistry Letters
Antibody–drug conjugates (ADCs) are a novel modality that allows targeted delivery of potent therapeutic agents to the desired site. Herein we report our discovery of NAMPT inhibitors as a novel nonantimitotic payload for ADCs. The resulting anti-c
Autor:
Pistorius, Dominik1 (AUTHOR) dominik.pistorius@novartis.com, Buntin, Kathrin1 (AUTHOR), Weber, Eric1 (AUTHOR), Richard, Etienne1 (AUTHOR), Bouquet, Caroline1 (AUTHOR), Wollbrett, Séverine1 (AUTHOR), Regenass, Hugo1 (AUTHOR), Peón, Victor1 (AUTHOR), Böhm, Marcel1 (AUTHOR), Kessler, Régis1 (AUTHOR), Gempeler, Thomas1 (AUTHOR), Haberkorn, Anne2 (AUTHOR), Wimmer, Laurin3 (AUTHOR), Lanshoeft, Christian4 (AUTHOR), Davis, John5 (AUTHOR), Hainzl, Dominik5 (AUTHOR), D'Alessio, Joseph Anthony6 (AUTHOR), Manchado, Eusebio2 (AUTHOR), Petersen, Frank1 (AUTHOR)
Publikováno v:
Chemistry - A European Journal. 2/7/2022, Vol. 28 Issue 8, p1-6. 6p.