Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Joseph Amann"'
Autor:
Luong T. H. Nguyen, Jingjing Zhang, Xilal Y. Rima, Xinyu Wang, Kwang Joo Kwak, Tamio Okimoto, Joseph Amann, Min Jin Yoon, Takehito Shukuya, Chi‐Ling Chiang, Nicole Walters, Yifan Ma, Donald Belcher, Hong Li, Andre F. Palmer, David P. Carbone, L. James Lee, Eduardo Reátegui
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 9, Pp n/a-n/a (2022)
Abstract Conventional PD‐L1 immunohistochemical tissue biopsies only predict 20%–40% of non‐small cell lung cancer (NSCLC) patients that will respond positively to anti‐PD‐1/PD‐L1 immunotherapy. Herein, we present an immunogold biochip to
Externí odkaz:
https://doaj.org/article/146b93eb927b403f95099c23ef145b70
Autor:
Rajeswara Rao Arasada, Konstantin Shilo, Tadaaki Yamada, Jianying Zhang, Seiji Yano, Rashelle Ghanem, Walter Wang, Shinji Takeuchi, Koji Fukuda, Nobuyuki Katakami, Keisuke Tomii, Fumitaka Ogushi, Yasuhiko Nishioka, Tiffany Talabere, Shrilekha Misra, Wenrui Duan, Paolo Fadda, Mohammad A. Rahman, Patrick Nana-Sinkam, Jason Evans, Joseph Amann, Elena E. Tchekneva, Mikhail M. Dikov, David P. Carbone
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Treatment of EGFR mutant non-small cell lung cancer (NSCLC) often develops resistance to EGFR TKIs. In this study, the authors discover a non-canonical activation of β-catenin signaling through Notch3 as a mechanism of adaptation to and resistance t
Externí odkaz:
https://doaj.org/article/f0b02e3948464f6081e96b751e406253
Autor:
Brandon Rodriguez, Veronica Jaramillo, Vanessa Wolf, Esteban Bautista, Jennifer Portillo, Alexandra Brouke, Ashley Min, Andrea Melendez, Joseph Amann, Abdon Pena-Francesch, Jared Ashcroft
Publikováno v:
Journal of Technology and Science Education, Vol 8, Iss 1, Pp 86-95 (2018)
A multidisciplinary science experiment was performed in K-12 classrooms focusing on the interconnection of technology with geology and chemistry. The engagement and passion for science of over eight hundred students across twenty-one classrooms, util
Externí odkaz:
https://doaj.org/article/f9ab201576a1460fa5a6db4e69822cde
Autor:
Luiz H Araujo, Cynthia Timmers, Konstantin Shilo, Weiqiang Zhao, Jianying Zhang, Lianbo Yu, Thanemozhi G Natarajan, Clinton J Miller, Ayse Selen Yilmaz, Tom Liu, Joseph Amann, José Roberto Lapa E Silva, Carlos Gil Ferreira, David P Carbone
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143092 (2015)
Tumor specimens are often preserved as formalin-fixed paraffin-embedded (FFPE) tissue blocks, the most common clinical source for DNA sequencing. Herein, we evaluated the effect of pre-sequencing parameters to guide proper sample selection for target
Externí odkaz:
https://doaj.org/article/9c0d6c4bbe984059b2385d1738e3bb68
Autor:
Jason V Evans, Shankar Suman, Mounika Uttam L Goruganthu, Elena E Tchekneva, Shuxiao Guan, Rajeswara Rao Arasada, Anneliese Antonucci, Longzhu Piao, Irina Ilgisonis, Andrey A Bobko, Benoit Driesschaert, Roman V Uzhachenko, Rebecca Hoyd, Alexandre Samouilov, Joseph Amann, Ruohan Wu, Lai Wei, Aaditya Pallerla, Sergey V Ryzhov, Igor Feoktistov, Kyungho P Park, Takefumi Kikuchi, Julio Castro, Alla V Ivanova, Thanigaivelan Kanagasabai, Dwight H Owen, Daniel J Spakowicz, Jay L Zweier, David P Carbone, Sergey V Novitskiy, Valery V Khramtsov, Anil Shanker, Mikhail M Dikov
Publikováno v:
JNCI: Journal of the National Cancer Institute.
Background We investigated the role of A2B-adenosine receptor (A2BAR) in regulating immunosuppressive metabolic stress in the tumor microenvironment (TME). Novel A2BAR antagonist PBF-1129 was tested for anti-tumor activity in animals and evaluated fo
Autor:
Dwight Owen, Lai Wei, Mikhail Dikov, Shankar Suman, Ruohan Wu, Joseph Amann, Catherine Schweitzer, Sarah Ferguson, Michael Smith, Julio Castro, Erin Bertino, Peter Shields, Kai He, Carolyn Presley, Gregory Otterson, David Carbone
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Luong T. H. Nguyen, Jingjing Zhang, Xilal Y. Rima, Xinyu Wang, Kwang Joo Kwak, Tamio Okimoto, Joseph Amann, Min Jin Yoon, Takehito Shukuya, Chi‐Ling Chiang, Nicole Walters, Yifan Ma, Donald Belcher, Hong Li, Andre F. Palmer, David P. Carbone, L. James Lee, Eduardo Reátegui
Publikováno v:
Journal of Extracellular Vesicles. 11
Autor:
Aaditya Pallerla, Bailey Conrad, Amna Bibi, Nyelia Williams, Caroline Wheeler, Rebecca Hoyd, Shankar Suman, Joseph Amann, Yangyang Liu, Marisa Bittoni, Shiqi Zhang, Madison Grogan, Alvin Anand, Najma Afrah, Carolyn Presley, Fred K. Tabung, Lang Li, Yael Vodovotz, Jiangjiang Zhu, David P. Carbone, Steven K. Clinton, Daniel Spakowicz
Publikováno v:
Cancer Research. 83:4435-4435
Rational manipulation of the gut microbiome by diet or other interventions is a promising approach to improving the efficacy and safety of cancer immunotherapy. However, linking lifestyle variables to specific microbial populations and the host immun
Autor:
Daniel Spakowicz, Rebecca Hoyd, Caroline E. Wheeler, Nyelia Williams, Amna Bibi, Marium Husain, Srichandhana Rajamouli, Shankar Suman, Joseph Amann, Madison Grogan, Pooja Vibhakar, Dwight H. Owen, David P. Carbone, Ashley Rosko, Christin E. Burd, Carolyn J. Presley
Publikováno v:
Cancer Research. 83:A021-A021
This abstract is being presented as a short talk in the scientific program. A full abstract is available in the Short Talks from Proffered Abstracts section (PR004) of the Conference Proceedings. Citation Format: Daniel Spakowicz, Rebecca Hoyd, Carol
Autor:
Daniel Spakowicz, Rebecca Hoyd, Caroline E. Wheeler, Nyelia Williams, Amna Bibi, Marium Husain, Srichandhana Rajamouli, Shankar Suman, Joseph Amann, Madison Grogan, Pooja Vibhakar, Dwight H. Owen, David P. Carbone, Ashley Rosko, Christin E. Burd, Carolyn J. Presley
Publikováno v:
Cancer Research. 83:PR004-PR004
The gut microbiome changes with age and affects many aspects of human health, including response to cancer treatments. Cancer survival rates have improved with new treatment options, including immune checkpoint blockade (ICB); however, the objective