Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Joseph A.M.J.L. Janssen"'
Publikováno v:
Cells, Vol 10, Iss 2, p 383 (2021)
Complex immunological mechanisms underlie the pathogenesis of thyroid-associated ophthalmopathy (TAO). Historical models of Graves’ disease and TAO have focused almost entirely on autoimmune reactivity directed against the thyrotropin receptor (TSH
Externí odkaz:
https://doaj.org/article/ff34779774784e98987f5bdc49a2c0ca
Autor:
Joseph A.M.J.L. Janssen
Publikováno v:
Cells, Vol 9, Iss 4, p 862 (2020)
Insulin-like growth factor-I (IGF-I) and insulin-like growth factor-II (IGF-II) play a crucial factor in the growth, differentiation and survival of cells in health and disease. IGF-I and IGF-II primarily activate the IGF-I receptor (IGF-IR), which i
Externí odkaz:
https://doaj.org/article/a11a7e05c00142218ac007f12e3508dc
Publikováno v:
Frontiers in Endocrinology, Vol 5 (2014)
The IGF-I Receptor (IGF-IR) has been studied as an anti-cancer target. However, monotherapy trials with IGF-IR targeted antibodies or with IGF-IR specific tyrosine kinase inhibitors has, overall, been very disappointing in the clinical setting. This
Externí odkaz:
https://doaj.org/article/993d28a6203644aaa3b999e4bd34eb68
Autor:
Naomi E. Allen, Timothy J. Key, Regina G. Ziegler, Noel S. Weiss, Nicholas J. Wald, Mathilde Touvier, Catherine M. Tangen, Akiko Tamakoshi, Pär Stattin, Meir J. Stampfer, Gianluca Severi, Jeannette M. Schenk, Catherine Schaefer, Monique J. Roobol, Alison J. Price, Michael N. Pollak, Elizabeth A. Platz, Domenico Palli, Kotaro Ozasa, Marian L. Neuhouser, David E. Neal, Joan K. Morris, Kazuya Mikami, E. Jeffrey Metter, Loic Le Marchand, Tatsuhiko Kubo, Rudolf Kaaks, Joseph A.M.J.L. Janssen, Robert N. Hoover, Serge Hercberg, Kathy J. Helzlsouer, Freddie C. Hamdy, Laurel A. Habel, Marc J. Gunter, Edward L. Giovannucci, Graham G. Giles, Pilar Galan, Luigi Ferrucci, Jenny L. Donovan, Mélanie Deschasaux, Michael B. Cook, Maria-Dolores Chirlaque, Chu Chen, June M. Chan, H. Bas Bueno-de-Mesquita, Amanda Black, Demetrius Albanes, Jeff M.P. Holly, Richard M. Martin, Paul N. Appleby, Ruth C. Travis
Supplementary material and methods: supplementary information on data collection, statistical analyses, and presentation of results in the figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a4c100f694cedcc5df385108ea4885
https://doi.org/10.1158/0008-5472.22410381.v1
https://doi.org/10.1158/0008-5472.22410381.v1
Autor:
Naomi E. Allen, Timothy J. Key, Regina G. Ziegler, Noel S. Weiss, Nicholas J. Wald, Mathilde Touvier, Catherine M. Tangen, Akiko Tamakoshi, Pär Stattin, Meir J. Stampfer, Gianluca Severi, Jeannette M. Schenk, Catherine Schaefer, Monique J. Roobol, Alison J. Price, Michael N. Pollak, Elizabeth A. Platz, Domenico Palli, Kotaro Ozasa, Marian L. Neuhouser, David E. Neal, Joan K. Morris, Kazuya Mikami, E. Jeffrey Metter, Loic Le Marchand, Tatsuhiko Kubo, Rudolf Kaaks, Joseph A.M.J.L. Janssen, Robert N. Hoover, Serge Hercberg, Kathy J. Helzlsouer, Freddie C. Hamdy, Laurel A. Habel, Marc J. Gunter, Edward L. Giovannucci, Graham G. Giles, Pilar Galan, Luigi Ferrucci, Jenny L. Donovan, Mélanie Deschasaux, Michael B. Cook, Maria-Dolores Chirlaque, Chu Chen, June M. Chan, H. Bas Bueno-de-Mesquita, Amanda Black, Demetrius Albanes, Jeff M.P. Holly, Richard M. Martin, Paul N. Appleby, Ruth C. Travis
Supplementary Figure Legends for Figures S1-S15.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f969779ec1e40e299a380258234b6f28
https://doi.org/10.1158/0008-5472.22410384
https://doi.org/10.1158/0008-5472.22410384
Autor:
Naomi E. Allen, Timothy J. Key, Regina G. Ziegler, Noel S. Weiss, Nicholas J. Wald, Mathilde Touvier, Catherine M. Tangen, Akiko Tamakoshi, Pär Stattin, Meir J. Stampfer, Gianluca Severi, Jeannette M. Schenk, Catherine Schaefer, Monique J. Roobol, Alison J. Price, Michael N. Pollak, Elizabeth A. Platz, Domenico Palli, Kotaro Ozasa, Marian L. Neuhouser, David E. Neal, Joan K. Morris, Kazuya Mikami, E. Jeffrey Metter, Loic Le Marchand, Tatsuhiko Kubo, Rudolf Kaaks, Joseph A.M.J.L. Janssen, Robert N. Hoover, Serge Hercberg, Kathy J. Helzlsouer, Freddie C. Hamdy, Laurel A. Habel, Marc J. Gunter, Edward L. Giovannucci, Graham G. Giles, Pilar Galan, Luigi Ferrucci, Jenny L. Donovan, Mélanie Deschasaux, Michael B. Cook, Maria-Dolores Chirlaque, Chu Chen, June M. Chan, H. Bas Bueno-de-Mesquita, Amanda Black, Demetrius Albanes, Jeff M.P. Holly, Richard M. Martin, Paul N. Appleby, Ruth C. Travis
The role of insulin-like growth factors (IGF) in prostate cancer development is not fully understood. To investigate the association between circulating concentrations of IGFs (IGF-I, IGF-II, IGFBP-1, IGFBP-2, and IGFBP-3) and prostate cancer risk, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eeae94674de29978b484eedd64f442b
https://doi.org/10.1158/0008-5472.c.6507978
https://doi.org/10.1158/0008-5472.c.6507978
Autor:
Naomi E. Allen, Timothy J. Key, Regina G. Ziegler, Noel S. Weiss, Nicholas J. Wald, Mathilde Touvier, Catherine M. Tangen, Akiko Tamakoshi, Pär Stattin, Meir J. Stampfer, Gianluca Severi, Jeannette M. Schenk, Catherine Schaefer, Monique J. Roobol, Alison J. Price, Michael N. Pollak, Elizabeth A. Platz, Domenico Palli, Kotaro Ozasa, Marian L. Neuhouser, David E. Neal, Joan K. Morris, Kazuya Mikami, E. Jeffrey Metter, Loic Le Marchand, Tatsuhiko Kubo, Rudolf Kaaks, Joseph A.M.J.L. Janssen, Robert N. Hoover, Serge Hercberg, Kathy J. Helzlsouer, Freddie C. Hamdy, Laurel A. Habel, Marc J. Gunter, Edward L. Giovannucci, Graham G. Giles, Pilar Galan, Luigi Ferrucci, Jenny L. Donovan, Mélanie Deschasaux, Michael B. Cook, Maria-Dolores Chirlaque, Chu Chen, June M. Chan, H. Bas Bueno-de-Mesquita, Amanda Black, Demetrius Albanes, Jeff M.P. Holly, Richard M. Martin, Paul N. Appleby, Ruth C. Travis
Supplementary tables and figures showing study and assay characteristics, correlations between analytes, and the relationships of the analytes with prostate cancer risk overall, by study and study design, and subdivided by clinical and other characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fa0fa8f7e0261fe74ad4dccca7e499
https://doi.org/10.1158/0008-5472.22410378
https://doi.org/10.1158/0008-5472.22410378
Autor:
Joseph A.M.J.L. Janssen
Publikováno v:
International Journal of Molecular Sciences. 24(5)
The metabolic syndrome is a cluster of overlapping conditions resulting in an increased incidence of type 2 diabetes, cardiovascular disease, and cancer. In the last few decades, prevalence of the metabolic syndrome in the Western world has reached e
Autor:
Joseph A.M.J.L. Janssen
Publikováno v:
International journal of molecular sciences. 23(15)
Recent data suggests that (pre)diabetes onset is preceded by a period of hyperinsulinemia. Consumption of the “modern” Western diet, over-nutrition, genetic background, decreased hepatic insulin clearance, and fetal/metabolic programming may incr
Autor:
Joseph A.M.J.L. Janssen
Publikováno v:
Netherlands Journal of Medicine, 75(7), 263-264. Van Zuiden Communications
Scopus-Elsevier
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a3507de832ffa9e9b70014f3a1b3796e
https://pure.eur.nl/en/publications/49de15f5-3e16-4bf4-a5a7-29b665fea9b2
https://pure.eur.nl/en/publications/49de15f5-3e16-4bf4-a5a7-29b665fea9b2