Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Joseph A. Westrich"'
Autor:
Nathaniel D. Denkers, Erin E. McNulty, Caitlyn N. Kraft, Amy V. Nalls, Joseph A. Westrich, Edward A. Hoover, Candace K. Mathiason
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 10, Pp 2118-2127 (2024)
Chronic wasting disease (CWD) affects cervids in North America, Asia, and Scandinavia. CWD is unique in its efficient spread, partially because of contact with infectious prions shed in secreta. To assess temporal profiles of CWD prion shedding, we c
Externí odkaz:
https://doaj.org/article/5ddaf5bafe3e40ae9c39954d6f944a01
Autor:
Joseph A. Westrich, Erin E. McNulty, Madison Stoltz, Tyler J. Sherman, Molly Carpenter, Mollie Burton, Amy Nalls, Hennio S. Rubio, Audrey Sandoval, Christie Mayo, Candace K. Mathiason
Publikováno v:
Viruses, Vol 16, Iss 10, p 1593 (2024)
Bluetongue virus (BTV) is a prevalent midge-borne pathogen that infects ruminant species worldwide. BTV infections range from asymptomatic to lethal, with mechanisms that determine the severity of infection remaining largely undefined. Although it is
Externí odkaz:
https://doaj.org/article/7ab211bb71fa4927b53eeb3194dd35f5
Autor:
Louis Cicchini, Rachel Z. Blumhagen, Joseph A. Westrich, Mallory E. Myers, Cody J. Warren, Charlotte Siska, David Raben, Katerina J. Kechris, Dohun Pyeon
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Human papillomavirus (HPV) infection distinctly alters methylation patterns in HPV-associated cancer. We have recently reported that HPV E7-dependent promoter hypermethylation leads to downregulation of the chemokine CXCL14 and suppression o
Externí odkaz:
https://doaj.org/article/b1daac7ff6fd46fa8f98a8fd822bbdf3
Autor:
Louis Cicchini, Joseph A. Westrich, Tao Xu, Daniel W. Vermeer, Jennifer N. Berger, Eric T. Clambey, Denis Lee, John I. Song, Paul F. Lambert, Robert O. Greer, John H. Lee, Dohun Pyeon
Publikováno v:
mBio, Vol 7, Iss 3 (2016)
ABSTRACT High-risk human papillomaviruses (HPVs) are causally associated with multiple human cancers. Previous studies have shown that the HPV oncoprotein E7 induces immune suppression; however, the underlying mechanisms remain unknown. To understand
Externí odkaz:
https://doaj.org/article/968814f4f50343f0bc8be64a70db166d
Publikováno v:
Viruses, Vol 10, Iss 2, p 82 (2018)
Viruses have evolved various mechanisms to evade host immunity and ensure efficient viral replication and persistence. Several DNA tumor viruses modulate host DNA methyltransferases for epigenetic dysregulation of immune-related gene expression in ho
Externí odkaz:
https://doaj.org/article/0d886e1f354849a481ed555cb9491f0a
Publikováno v:
Viruses, Vol 9, Iss 8, p 233 (2017)
The apolipoprotein B messenger RNA-editing, enzyme-catalytic, polypeptide-like 3 (APOBEC3) family of cytidine deaminases plays an important role in the innate immune response to viral infections by editing viral genomes. However, the cytidine deamina
Externí odkaz:
https://doaj.org/article/45c03c53210248a4836307eb3f4131a0
Autor:
Jennifer Kopanke, Molly Carpenter, Justin Lee, Kirsten Reed, Case Rodgers, Mollie Burton, Kierra Lovett, Joseph A. Westrich, Erin McNulty, Emily McDermott, Carly Barbera, Sean Cavany, Jason R. Rohr, T. Alex Perkins, Candace K. Mathiason, Mark Stenglein, Christie Mayo
Publikováno v:
Annual Review of Animal Biosciences. 10:303-324
Bluetongue virus (BTV) is an arthropod-borne, segmented double-stranded RNA virus that can cause severe disease in both wild and domestic ruminants. BTV evolves via several key mechanisms, including the accumulation of mutations over time and the rea
Autor:
Rushika Perera, Candace K. Mathiason, Amy V. Nalls, Erin McNulty, Joel Rovnak, Brian D. Foy, Megan R. Miller, Marisa J. Edmonds, Joseph A. Westrich
Publikováno v:
The Journal of General Virology
An infectious agent’s pathogenic and transmission potential is heavily influenced by early events during the asymptomatic or subclinical phase of disease. During this phase, the presence of infectious agent may be relatively low. An important examp
Autor:
David Raben, Dohun Pyeon, John H. Lee, Daniel W. Vermeer, Louis Cicchini, Alexa Silva, William C. Spanos, Jill E. Slansky, Jennifer N. Berger, Stephanie Bonney, Joseph A. Westrich, Robert O. Greer, John I. Song
Publikováno v:
Oncogene
Evasion of the host immune responses is critical for both persistent human papillomavirus (HPV) infection and associated cancer progression. We have previously shown that expression of the homeostatic chemokine CXCL14 is significantly downregulated b
Publikováno v:
Mol Carcinog
The chemokine CXCL14 is a highly conserved, homeostatic chemokine which is constitutively expressed in skin epithelia. Responsible for immune cell recruitment and maturation, as well as impacting epithelial cell motility, CXCL14 contributes to the es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd38eb437365aa9947496739804c20d6
https://europepmc.org/articles/PMC7282946/
https://europepmc.org/articles/PMC7282946/