Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Joseph A. Wahle"'
Autor:
Luise Sternberg, Yina H. Huang, A. Helena Jonsson, Karsten Sauer, Anthony R. French, Joseph A. Wahle, Wayne M. Yokoyama, Stephanie Rigaud, Sabine Siegemund, Eugene Park
Publikováno v:
Blood. 121:286-297
Natural killer (NK) cells have important functions in cancer immunosurveillance, BM allograft rejection, fighting infections, tissue homeostasis, and reproduction. NK cell–based therapies are promising treatments for blood cancers. Overcoming their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c57a8746aff4beb32a0dafe33b66f4f
https://doi.org/10.1182/blood-2012-05-429241
https://doi.org/10.1182/blood-2012-05-429241
Publikováno v:
The Journal of Experimental Medicine
In MHC class I–deficient hosts, natural killer (NK) cells are hyporesponsive to cross-linking of activation receptors. Functional competence requires engagement of a self–major histocompatability complex (MHC) class I–specific inhibitory recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aecad7419b39b5421c1e05e2c8d606ba
https://doi.org/10.1084/jem.20100986
https://doi.org/10.1084/jem.20100986
Autor:
Joseph A. Wahle, Robert D. Kendig, William G. Kerr, Jerry Wu, Harshani R. Lawrence, Kim H. T. Paraiso, Liwei Chen
Publikováno v:
The Journal of Immunology. 179:8009-8015
We have previously demonstrated that the NKR repertoire is profoundly disrupted by SHIP deficiency. This repertoire disruption is characterized by receptor dominance where inhibitory signals from 2B4 repress killing of complex targets expressing MHC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea8c5d58ade5dc25e27f6c80c13e7bf
https://doi.org/10.4049/jimmunol.179.12.8009
https://doi.org/10.4049/jimmunol.179.12.8009
Autor:
Joseph A. Wahle, Kim H. T. Paraiso, William G. Kerr, Charles L. Sentman, Emily L. Goll, Amy L. Costello
Publikováno v:
The Journal of Immunology. 176:7165-7169
Inhibitory receptors that recognize MHC class I molecules regulate NK cell responses and self-tolerance. Recent evidence indicates that self-ligands not present in the MHC locus also can modulate NK function. In this study, we show that an inhibitory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515e1cf1e04f14b48d1092e690efb562
https://doi.org/10.4049/jimmunol.176.12.7165
https://doi.org/10.4049/jimmunol.176.12.7165
Autor:
Joseph A. Wahle, Eugene Park, Karsten Sauer, Sabine Siegemund, Helena Jonsson, Luise Sternberg, Wayne M. Yokoyama, Anthony R. French, Stephanie Rigaud
Publikováno v:
The FASEB Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::babd1eeac3927370292cb04c0a63d24f
https://doi.org/10.1096/fasebj.28.1_supplement.1013.1
https://doi.org/10.1096/fasebj.28.1_supplement.1013.1
Autor:
Amy L. Hazen, Joseph A. Wahle, William G. Kerr, Maikel P. Peppelenbosch, Gwenny M. Fuhler, Sander H. Diks
Publikováno v:
Journal of Proteome Research, 10(8), 3542-3550. American Chemical Society
The changes in signal transduction associated with the acquisition of specific cell fates remain poorly understood. We performed massive parallel assessment of kinase signatures of the radiations of the hematopoietic system, including long-term repop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68733598ccc3255b4309c7d49f607ed8
https://pure.eur.nl/en/publications/d09ff2ea-3d0d-4d37-8d10-104a8663e6d0
https://pure.eur.nl/en/publications/d09ff2ea-3d0d-4d37-8d10-104a8663e6d0
