Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joseph A. Truglia"'
Autor:
M Ra Crisp, BA Parker, Aaron Fleischauer, Joseph A. Truglia, Steven L. Soignet, Raymond P. Warrell, Fabio Benedetti
Publikováno v:
Leukemia. 12:1518-1521
The use of all-trans retinoic acid (RA) for remission induction markedly increases survival of patients with acute promyelocytic leukemia (APL) compared to patients treated solely with cytotoxic chemotherapy. However, clinical resistance to this agen
Publikováno v:
Diabetes Care. 15:588-589
Autor:
Joseph A. Truglia, Stefan C. Grant, Mark G. Kris, Vincent A. Miller, William P. Tong, James R. Rigas, Raymond P. Warrell
Publikováno v:
Lung Cancer. 18:192
Publikováno v:
Diabetologia. 29:798-801
The cellular mechanism(s) by which the biguanide, metformin, exerts its antihyperglycaemic effect was investigated. Rat adipocytes were either treated acutely (2 h) or maintained in a biochemically defined medium (20 h) in the presence or absence of
Autor:
Joseph A. Truglia, Alfred Stracher
Publikováno v:
Biochemical and biophysical research communications. 100(2)
Summary A calcium dependent sulfhydryl protease (CDSP) responsible for over 95% of the neutral protease activity of human platelets has been purified. CDSP is composed of two different polypeptide subunits of molecular weights estimated to be 80,000
Publikováno v:
The American journal of medicine. 79(2B)
Insulin resistance is a prominent feature of three clinical conditions: obesity, impaired glucose tolerance, and non-insulin-dependent (type II) diabetes mellitus. Numerous studies over the past 15 years have provided a better understanding, from bot
Publikováno v:
Diabetes. 37(2)
We evaluated the possibility that impaired insulin-receptor kinase activity contributes to insulin resistance by examining in vitro receptor tyrosine kinase activity and in situ receptor phosphorylation in four models of insulin resistance. Adipocyte