Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Joseph A. Tran"'
Autor:
Geeta Ahuja, Jae Ho Kim, Joseph Francis Tran, Siobhan Nnorom, Ahmed Ali, Mohammed Ibrahim, Ginette A. Okoye, Babak Shokrani, Jacqueline Dunmore-Griffith, Kirk Geter, Wayne A.I. Frederick, Lori Wilson
Publikováno v:
Journal of the National Medical Association. 114:290-294
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24577a152e1f91117d2260b64c0c7d16
https://doi.org/10.1016/j.jnma.2022.01.011
https://doi.org/10.1016/j.jnma.2022.01.011
α- and β-tubulin form heterodimers, with GTPase activity, that assemble into microtubules. Like other GTPases, the nucleotide-bound state of tubulin heterodimers controls whether the molecules are in a biologically active or inactive state. While
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ca57f076e4f9b784a03035c5447a986
https://doi.org/10.1101/2023.05.09.539990
https://doi.org/10.1101/2023.05.09.539990
Publikováno v:
Bioinformatics. 39
Motivation Computational inference of genome organization based on Hi-C sequencing has greatly aided the understanding of chromatin and nuclear organization in three dimensions (3D). However, existing computational methods fail to address the cell po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8399eaf15f723ea7cf3d79701ceef708
https://doi.org/10.1093/bioinformatics/btad314
https://doi.org/10.1093/bioinformatics/btad314
Autor:
Siobhan O. Nnorom, Hana Baig, Oluwasegun A. Akinyemi, Joseph H. Tran, Jeduthun Harris, Fady Sidhom, Wayne A. Frederick, Edward E. Cornwell, Lori L. Wilson
Publikováno v:
The American Surgeon. 88:1484-1489
Introduction Thyroid cancer incidence has increased substantially in the past 4 decades, estimated at 3.5% annually. Incidence is highest in white patients, yet black patients have the worst survival. Racial/ethnic differences in presentation and out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43cc190a8f57a5cdfbdb01221ad614b2
https://doi.org/10.1177/00031348221082282
https://doi.org/10.1177/00031348221082282
Publikováno v:
Nucleic acids research. 50(20)
The chromatin associated with the nuclear lamina (NL) is referred to as lamina-associated domains (LADs). Here, we present an adaptation of the tyramide-signal amplification sequencing (TSA-seq) protocol, which we call chromatin pull down-based TSA-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a27181bbba27e558e0e25e6f5ee4b70
https://pubmed.ncbi.nlm.nih.gov/36130229
https://pubmed.ncbi.nlm.nih.gov/36130229
The computational inference of genome organization based on Hi-C sequencing has greatly aided the understanding of chromatin and nuclear organization in three dimensions (3D). However, existing computational methods used to infer sub-compartments fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc2695a99b6f8f4c5587865da0477932
https://doi.org/10.1101/2022.06.27.497761
https://doi.org/10.1101/2022.06.27.497761
Autor:
Amir Vahabikashi, Suganya Sivagurunathan, Fiona Ann Sadsad Nicdao, Yu Long Han, Chan Young Park, Mark Kittisopikul, Xianrong Wong, Joseph R. Tran, Gregg G. Gundersen, Karen L. Reddy, G. W. Gant Luxton, Ming Guo, Jeffrey J. Fredberg, Yixian Zheng, Stephen A. Adam, Robert D. Goldman
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The ability of a cell to regulate its mechanical properties is central to its function. Emerging evidence suggests that interactions between the cell nucleus and cytoskeleton influence cell mechanics through poorly understood mechanisms. Here we cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30db962e59a0d9fa90a517242523184b
https://doi.org/10.1073/pnas.2121816119
https://doi.org/10.1073/pnas.2121816119
A large fraction of heterochromatin in the metazoan genome is associated with the nuclear lamina (NL) in interphase nuclei. This heterochromatin is often referred to as Lamina-Associated Domains (LADs) and are often mapped from cell populations async
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bab7d5fca6c2bb77d0f13bf2e8312d51
https://doi.org/10.1101/2021.01.03.425156
https://doi.org/10.1101/2021.01.03.425156
Autor:
James J. Moresco, Stephen A. Adam, John R. Yates, Robert D. Goldman, Yixian Zheng, Joseph R. Tran, Danielle I. Paulson
Publikováno v:
The Journal of Cell Biology
The APEX2 proximity ligation method can identify RNA, protein, and DNA interacting with or in proximity to the nuclear lamina. This work suggests a potential regulation of mRNAs containing long 3′ UTRs and uncovers variation in lamina-associated ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0f0f89c9100f1ac4c8fa8514bd512c
https://doi.org/10.1083/jcb.202002129
https://doi.org/10.1083/jcb.202002129
Autor:
Mark Kittisopikul, Joseph R. Tran, Khuloud Jaqaman, Stephen A. Adam, Yixian Zheng, Takeshi Shimi, Ohad Medalia, Robert D. Goldman, Meltem Tatli
Publikováno v:
The Journal of Cell Biology
Structured illumination microscopy, cryo-ET, and computational analyses reveal that nuclear pore complexes (NPCs) and specific lamins spatially distribute in a codependent manner. Knocking out certain lamin genes or knocking down particular nucleopor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847f99037eb0fea896bca72446036302
https://pubmed.ncbi.nlm.nih.gov/33570570
https://pubmed.ncbi.nlm.nih.gov/33570570