Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Joseph A. Mattocks"'
Autor:
Ziye Dong, Joseph A. Mattocks, Gauthier J.-P. Deblonde, Dehong Hu, Yongqin Jiao, Joseph A. Cotruvo, Dan M. Park
Publikováno v:
ACS Central Science, Vol 7, Iss 11, Pp 1798-1808 (2021)
Externí odkaz:
https://doaj.org/article/124da8cb005748ebb1e1992abb12f3f5
Autor:
Joseph A. Mattocks, Jonathan J. Jung, Chi-Yun Lin, Ziye Dong, Neela H. Yennawar, Emily R. Featherston, Christina S. Kang-Yun, Timothy A. Hamilton, Dan M. Park, Amie K. Boal, Joseph A. Cotruvo
Publikováno v:
Nature. 618:87-93
Technologically critical rare-earth elements are notoriously difficult to separate, owing to their subtle differences in ionic radius and coordination number1–3. The natural lanthanide-binding protein lanmodulin (LanM)4,5 is a sustainable alternati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87ef3925ff1f92e0d3e81c719fce62cc
https://doi.org/10.1038/s41586-023-05945-5
https://doi.org/10.1038/s41586-023-05945-5
Autor:
Kirsten E. Martin, Joseph A. Mattocks, Dariusz Śmiłowicz, Eduardo Aluicio-Sarduy, Jennifer N. Whetter, Jonathan W. Engle, Joseph A. Cotruvo, Eszter Boros
Publikováno v:
RSC Chemical Biology.
This work describes successful radiochemical labeling and subsequent in vivo evaluation of radiolanthanide-tagged versions of lanmodulin (LanM), a lathanide-binding protein.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edf393dd987ae626669f026cba55c88a
https://doi.org/10.1039/d3cb00020f
https://doi.org/10.1039/d3cb00020f
Autor:
Gauthier J.-P. Deblonde, Huan Wang, Mavrik Zavarin, Eric M. Gale, Joseph A. Cotruvo, Annie B. Kersting, Joseph A. Mattocks
Publikováno v:
Journal of the American Chemical Society. 143:15769-15783
Anthropogenic radionuclides, including long-lived heavy actinides such as americium and curium, represent the primary long-term challenge for management of nuclear waste. The potential release of these wastes into the environment necessitates underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7149e731ea5f0a2cfb2f3eb2ccad2ad
https://doi.org/10.1021/jacs.1c07103
https://doi.org/10.1021/jacs.1c07103
Autor:
Joseph A. Cotruvo, Dan M. Park, Joseph A. Mattocks, Yongqin Jiao, Gauthier J.-P. Deblonde, David W. Reed
Publikováno v:
Inorganic Chemistry. 59:11855-11867
Lanmodulin (LanM) is a recently discovered protein that undergoes a large conformational change in response to rare-earth elements (REEs). Here, we use multiple physicochemical methods to demonstrate that LanM is the most selective macromolecule for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0f27872571417f4cb289c205e5825b
https://doi.org/10.1021/acs.inorgchem.0c01303
https://doi.org/10.1021/acs.inorgchem.0c01303
Autor:
Gauthier J.-P. Deblonde, Joseph A. Mattocks, Huan Wang, Eric M. Gale, Annie B. Kersting, Mavrik Zavarin, Joseph A. Cotruvo
Publikováno v:
Journal of the American Chemical Society. 144:23708-23708
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b67b4a84d5b27803f9f4de9fe7321a12
https://doi.org/10.1021/jacs.2c12196
https://doi.org/10.1021/jacs.2c12196
Autor:
Ziye Dong, Joseph A. Cotruvo, Joseph A. Mattocks, Mavrik Zavarin, Paul T. Wooddy, Gauthier J.-P. Deblonde
Publikováno v:
Science Advances
Description
Demystifying the elusive chemistry of actinium leads to novel opportunities in radioisotope production and nuclear medicine.
Actinium-based therapies could revolutionize cancer medicine but remain tantalizing due to the difficul
Demystifying the elusive chemistry of actinium leads to novel opportunities in radioisotope production and nuclear medicine.
Actinium-based therapies could revolutionize cancer medicine but remain tantalizing due to the difficul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a005f40ed643daacb4162a69e25590f
https://doi.org/10.1126/sciadv.abk0273
https://doi.org/10.1126/sciadv.abk0273
Autor:
Gauthier Deblonde, Joseph A. Mattocks, Ziye Dong, Paul T. Wooddy, Joseph A. Jr. Cotruvo, Mavrik Zavarin
Actinium-based therapies could revolutionize cancer medicine but remain tantalizing due to the difficulties in studying Ac chemistry. Current efforts focus on small synthetic chelators, limiting radioisotope complexation and purification efficiencies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955bbd398ffe11d2a72e3cb6fe29dd38
https://doi.org/10.26434/chemrxiv.14763426.v1
https://doi.org/10.26434/chemrxiv.14763426.v1
Publikováno v:
Methods in enzymology. 651
The recent discoveries of the first proteins that bind lanthanides as part of their biological function not only are relevant to the emerging field of lanthanide-dependent biology, but also hold promise to revolutionize the technologically critical r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c87c64035732eb77f1bb3a7ebd59978d
https://pubmed.ncbi.nlm.nih.gov/33888205
https://pubmed.ncbi.nlm.nih.gov/33888205
Publikováno v:
Methods in enzymology. 650
Recent work has revealed that certain lanthanides-in particular, the more earth-abundant, lighter lanthanides-play essential roles in pyrroloquinoline quinone (PQQ) dependent alcohol dehydrogenases from methylotrophic and non-methylotrophic bacteria.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e6d9ff8e13b23e7520efa07f8620679
https://pubmed.ncbi.nlm.nih.gov/33867019
https://pubmed.ncbi.nlm.nih.gov/33867019