Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Joseph A. Landry"'
Autor:
Gabor Egervari, Diana Akpoyibo, Tanni Rahman, John F. Fullard, James E. Callens, Joseph A. Landry, Annie Ly, Xianxiao Zhou, Noël Warren, Mads E. Hauberg, Gabriel Hoffman, Randy Ellis, Jacqueline-Marie N. Ferland, Michael L. Miller, Eva Keller, Bin Zhang, Panos Roussos, Yasmin L. Hurd
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Epigenetic mechanisms have emerged as contributors to the molecular impairments caused by exposure to environmental factors such as abused substances. Here the authors perform epigenetic profiling of the striatum and identify the tyrosine kinase FYN
Externí odkaz:
https://doaj.org/article/1d88bd91ce5342d1ae6c9fd044545db3
Autor:
Erin S. Calipari, Arthur Godino, Emily G. Peck, Marine Salery, Nicholas L. Mervosh, Joseph A. Landry, Scott J. Russo, Yasmin L. Hurd, Eric J. Nestler, Drew D. Kiraly
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Cocaine addiction is accompanied by dysfunction in neural circuits related to reward, but it is unclear how these adaptations occur. Here, authors identify granulocyte-colony stimulating factor as a potent mediator of cocaine-induced adaptations, and
Externí odkaz:
https://doaj.org/article/c2650a6a7cc84e57a9b370118f9135cd
Autor:
Eva E. Lancaster, Vladimir I. Vladimirov, Brien P. Riley, Joseph W. Landry, Roxann Roberson-Nay, Timothy P. York
Publikováno v:
Epigenetics, Vol 17, Iss 12, Pp 1753-1773 (2022)
Although epigenome-wide association studies (EWAS) have been successful in identifying DNA methylation (DNAm) patterns associated with disease states, any further characterization of etiologic mechanisms underlying disease remains elusive. This knowl
Externí odkaz:
https://doaj.org/article/b8531f524d2b47d39032fc8f0a750f95
Autor:
Teddy O. Uzamere, Prashanth Rajarajan, Aarthi Ramakrishnan, Henrietta Szutorisz, Joseph A. Landry, James E. Callens, Li Shen, Anissa Bara, Kristen J. Brennand, Claudia A. Vargas, Qammarah Martin, Yasmin L. Hurd, Eddie Loh, Randall J. Ellis, Amy L. Frick
Publikováno v:
Biological Psychiatry. 92:127-138
Background Cannabis remains one of the most widely abused drugs during pregnancy. In utero exposure to its principal psychoactive component, Δ9-tetrahydrocannabinol (THC), can result in long-term neuropsychiatric risk for the progeny. The current st
Autor:
Joseph W. Landry, David A. Gewirtz, Yves Pommier, William C.K. Pomerantz, Dipankar Bandyopadhyay, Paula D. Bos, Steve E. Kirberger, Xiaoyan Deng, Ryan Finnegan, Joshua Haueis, Syed Haqqani, Manjulata Singh, Ashish Vaidyanathan, Mallika Dammalapati, Hannah Ngo, Nga Dao, Yilun Sun, Liliya Tyutyunyk-Massey
Epigenetic regulators can modulate the effects of cancer therapeutics. To further these observations, we discovered that the bromodomain PHD finger transcription factor subunit (BPTF) of the nucleosome remodeling factor (NURF) promotes resistance to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bc0c883ceb3539d71fe27c779f70976
https://doi.org/10.1158/1541-7786.c.6545277.v1
https://doi.org/10.1158/1541-7786.c.6545277.v1
Autor:
Joseph W. Landry, David A. Gewirtz, Yves Pommier, William C.K. Pomerantz, Dipankar Bandyopadhyay, Paula D. Bos, Steve E. Kirberger, Xiaoyan Deng, Ryan Finnegan, Joshua Haueis, Syed Haqqani, Manjulata Singh, Ashish Vaidyanathan, Mallika Dammalapati, Hannah Ngo, Nga Dao, Yilun Sun, Liliya Tyutyunyk-Massey
Supplemental Figure 5. Selective BPTF Bromdomain Inhibitor AU1 Recapitulates Effects from BPTF KD in Human MDA-MB-231 and Mouse 66cl4 and 4T07 Cell Lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27eee3dab037824eb4c432997801db05
https://doi.org/10.1158/1541-7786.22526982
https://doi.org/10.1158/1541-7786.22526982
Autor:
Joseph W. Landry, David A. Gewirtz, Yves Pommier, William C.K. Pomerantz, Dipankar Bandyopadhyay, Paula D. Bos, Steve E. Kirberger, Xiaoyan Deng, Ryan Finnegan, Joshua Haueis, Syed Haqqani, Manjulata Singh, Ashish Vaidyanathan, Mallika Dammalapati, Hannah Ngo, Nga Dao, Yilun Sun, Liliya Tyutyunyk-Massey
Supplemental Figure 2. NURF Selectively Suppresses Toxicity to Topoisomerase 2 Poisons and Improves their DNA Damaging Effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14da1f0fee997c059dcc86cd19ec2637
https://doi.org/10.1158/1541-7786.22526991.v1
https://doi.org/10.1158/1541-7786.22526991.v1
Autor:
Joseph W. Landry, David A. Gewirtz, Yves Pommier, William C.K. Pomerantz, Dipankar Bandyopadhyay, Paula D. Bos, Steve E. Kirberger, Xiaoyan Deng, Ryan Finnegan, Joshua Haueis, Syed Haqqani, Manjulata Singh, Ashish Vaidyanathan, Mallika Dammalapati, Hannah Ngo, Nga Dao, Yilun Sun, Liliya Tyutyunyk-Massey
Supplemental Figure 4. Selective BPTF Bromdomain Inhibitor AU1 Recapitulates Effects from BPTF KD in 4T1 Cells and Tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8a1ae72d220a7e58c080efeb1f9ccb
https://doi.org/10.1158/1541-7786.22526985
https://doi.org/10.1158/1541-7786.22526985
Autor:
Joseph W. Landry, David A. Gewirtz, Yves Pommier, William C.K. Pomerantz, Dipankar Bandyopadhyay, Paula D. Bos, Steve E. Kirberger, Xiaoyan Deng, Ryan Finnegan, Joshua Haueis, Syed Haqqani, Manjulata Singh, Ashish Vaidyanathan, Mallika Dammalapati, Hannah Ngo, Nga Dao, Yilun Sun, Liliya Tyutyunyk-Massey
Supplemental Figure 3. Validation of Autophagy by Microscopy and ATG5 KD in 4T1 Cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6cea3399c1394e3e7d959a2f370c44
https://doi.org/10.1158/1541-7786.22526988.v1
https://doi.org/10.1158/1541-7786.22526988.v1
Autor:
Joseph W. Landry, Xiang-Yang Wang, Catherine I. Dumur, Mark Roberts, Tana Blevins, Vivian Chan, Carolyn Song, Aiman Alhazmi, Kristen Peterson, Suehyb G. Alkhatib, Kimberly Mayes
Enhanced CD8 T cell cytotoxicity to BPTF KD cells is not due to the OVA or pmel antigens.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a1f7d48d1d1b5594ae6409caab94fe
https://doi.org/10.1158/0008-5472.22410621
https://doi.org/10.1158/0008-5472.22410621