Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Joseph A. Kovacs"'
Autor:
Ousmane H. Cissé, Shelly J. Curran, H. Diego Folco, Yueqin Liu, Lisa Bishop, Honghui Wang, Elizabeth R. Fischer, A. Sally Davis, Christian Combs, Sabrina Thapar, John P. Dekker, Shiv Grewal, Melanie Cushion, Liang Ma, Joseph A. Kovacs
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Centromeres are constricted chromosomal regions that are essential for cell division. In eukaryotes, centromeres display a remarkable architectural and genetic diversity. The basis of centromere-accelerated evolution remains elusive. Here, w
Externí odkaz:
https://doaj.org/article/b90416d035844a13812402c4d792a37f
Autor:
Liang Ma, Isabella Lin, Summer T. Hunter, Barbara Blasi, Patrizia Danesi, Christiane Weissenbacher-Lang, Ousmane H. Cisse, Jamie L. Rothenburger, Joseph A. Kovacs
Publikováno v:
Journal of Fungi, Vol 10, Iss 5, p 355 (2024)
Despite its ubiquitous infectivity to mammals with strong host specificity, our current knowledge about Pneumocystis has originated from studies of merely 4% of extant mammalian species. Further studies of Pneumocystis epidemiology across a broader r
Externí odkaz:
https://doaj.org/article/2dd0cc5306db473f8147eca109d5ed37
Autor:
Emily L. Coffey, Liang Ma, Ousmane H. Cissé, Joseph A. Kovacs, Katie M. Minor, Antti Sukura, Patrizia Danesi, Steven G. Friedenberg, Jonah N. Cullen, Christiane Weissenbacher-Lang, Julie C. Nadeau, Amber M. Graham, Martin N. Granick, Natalie K. Branson, Kyle C. Branson, Barbara Blasi, Casandra M. Jacobs, Eva Furrow
Publikováno v:
Journal of Fungi, Vol 10, Iss 3, p 198 (2024)
Pet dogs are a valuable natural animal model for studying relationships between primary immunodeficiencies and susceptibility to Pneumocystis and other opportunistic respiratory pathogens. Certain breeds, such as the Cavalier King Charles Spaniel, ar
Externí odkaz:
https://doaj.org/article/ef1fcb60af49463f86b4803ae34b6116
Autor:
Ousmane H. Cissé, Liang Ma, John P. Dekker, Pavel P. Khil, Jung-Ho Youn, Jason M. Brenchley, Robert Blair, Bapi Pahar, Magali Chabé, Koen K. A. Van Rompay, Rebekah Keesler, Antti Sukura, Vanessa Hirsch, Geetha Kutty, Yueqin Liu, Li Peng, Jie Chen, Jun Song, Christiane Weissenbacher-Lang, Jie Xu, Nathan S. Upham, Jason E. Stajich, Christina A. Cuomo, Melanie T. Cushion, Joseph A. Kovacs
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Cissé, Ma et al. utilize genomic data from Pneumocystis species infecting macaques, rabbit, dogs and rats to investigate the molecular basis of host specificity in Pneumocystis. Their analyses provide insight to the specific adaptations enabling the
Externí odkaz:
https://doaj.org/article/907c65fcc47a4c35b7cdbbac023e26da
Autor:
Christiane Weissenbacher-Lang, Barbara Blasi, Patricia Bauer, Diana Binanti, Karin Bittermann, Lara Ergin, Carmen Högler, Tanja Högler, Magdalena Klier, Julia Matt, Nora Nedorost, Serenella Silvestri, Daniela Stixenberger, Liang Ma, Ousmane H. Cissé, Joseph A. Kovacs, Amélie Desvars-Larrive, Annika Posautz, Herbert Weissenböck
Publikováno v:
Journal of Fungi, Vol 9, Iss 2, p 220 (2023)
Pneumocystis spp. are thought to adapt to the lungs of potentially all mammals. However, the full host range, fungal burden and severity of infection are unknown for many species. In this study, lung tissue samples originating from 845 animals of 31
Externí odkaz:
https://doaj.org/article/9d0ec7b4df5340d099c45c1743f0d1a2
Publikováno v:
Journal of Fungi, Vol 8, Iss 6, p 645 (2022)
Pneumocystis is a fungal pathogen that can cause pneumonia in immunosuppressed hosts and subclinical infection in immunocompetent hosts. Mucosal-associated invariant T (MAIT) cells are unconventional lymphocytes with a semi-invariant T-cell receptor
Externí odkaz:
https://doaj.org/article/0cc7205eca8f4a41a45a84e227981448
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Environmental exposure has a significant impact on human health. While some airborne fungi can cause life-threatening infections, the impact of environment on fungal spore dispersal and transmission is poorly understood. The democratization
Externí odkaz:
https://doaj.org/article/da0829b7a1524354a2397abf9e69ef7d
Autor:
Liang Ma, Zehua Chen, Da Wei Huang, Ousmane H. Cissé, Jamie L. Rothenburger, Alice Latinne, Lisa Bishop, Robert Blair, Jason M. Brenchley, Magali Chabé, Xilong Deng, Vanessa Hirsch, Rebekah Keesler, Geetha Kutty, Yueqin Liu, Daniel Margolis, Serge Morand, Bapi Pahar, Li Peng, Koen K. A. Van Rompay, Xiaohong Song, Jun Song, Antti Sukura, Sabrina Thapar, Honghui Wang, Christiane Weissenbacher-Lang, Jie Xu, Chao-Hung Lee, Claire Jardine, Richard A. Lempicki, Melanie T. Cushion, Christina A. Cuomo, Joseph A. Kovacs
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Pneumocystis, a major opportunistic pathogen in patients with a broad range of immunodeficiencies, contains abundant surface proteins encoded by a multicopy gene family, termed the major surface glycoprotein (Msg) gene superfamily. This supe
Externí odkaz:
https://doaj.org/article/506cf3cdb75d42c089e62b4f90d2fba5
Autor:
Liang Ma, Zehua Chen, Da Wei Huang, Geetha Kutty, Mayumi Ishihara, Honghui Wang, Amr Abouelleil, Lisa Bishop, Emma Davey, Rebecca Deng, Xilong Deng, Lin Fan, Giovanna Fantoni, Michael Fitzgerald, Emile Gogineni, Jonathan M. Goldberg, Grace Handley, Xiaojun Hu, Charles Huber, Xiaoli Jiao, Kristine Jones, Joshua Z. Levin, Yueqin Liu, Pendexter Macdonald, Alexandre Melnikov, Castle Raley, Monica Sassi, Brad T. Sherman, Xiaohong Song, Sean Sykes, Bao Tran, Laura Walsh, Yun Xia, Jun Yang, Sarah Young, Qiandong Zeng, Xin Zheng, Robert Stephens, Chad Nusbaum, Bruce W. Birren, Parastoo Azadi, Richard A. Lempicki, Christina A. Cuomo, Joseph A. Kovacs
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Pneumocystis jirovecii is a fungus that can cause life-threatening pneumonia in immunocompromised patients. Here, the authors sequence the genomes of P. jirovecii and two other Pneumocystisspecies, and show the unexpected absence of chitin (a near un
Externí odkaz:
https://doaj.org/article/a63cc72f702b47298d73bf4e878df92d
Autor:
Ousmane H. Cissé, Liang Ma, Da Wei Huang, Pavel P. Khil, John P. Dekker, Geetha Kutty, Lisa Bishop, Yueqin Liu, Xilong Deng, Philippe M. Hauser, Marco Pagni, Vanessa Hirsch, Richard A. Lempicki, Jason E. Stajich, Christina A. Cuomo, Joseph A. Kovacs
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT Pneumocystis species are opportunistic mammalian pathogens that cause severe pneumonia in immunocompromised individuals. These fungi are highly host specific and uncultivable in vitro. Human Pneumocystis infections present major challenges b
Externí odkaz:
https://doaj.org/article/c0995cfe69d144e9b577c9ecad070400