Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Joseph A. Chadwick"'
Autor:
Phil F. Xie, Jaeho Chang, Paulina Siejka-Zielińska, Masato Inoue, Magdalena Drożdż, Joseph A. Chadwick, Thomas M. Carroll, Richard P. Owen, Michael J. White, Joseph Kaplinsky, Robert Amess, Mark Middleton, Skirmantas Kriaucionis, Chunxiao Song, Benjamin Schuster-Böckler, Xin Lu
Publikováno v:
Cancer Research. 83:LB131-LB131
Immune checkpoint inhibitors (ICI) were recently approved as a first-line treatment for inoperable esophageal adenocarcinomas (EAC) in combination with chemotherapy (CTX). Unfortunately, even though EAC has one of the highest tumor mutation burdens a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eccd42063a7f9f0e4dd17d03b4f7624
https://doi.org/10.1158/1538-7445.am2023-lb131
https://doi.org/10.1158/1538-7445.am2023-lb131
Autor:
Thomas M. Carroll, Joseph A. Chadwick, Richard P. Owen, Michael J. White, Joseph Kaplinsky, Iliana Peneva, Anna Frangou, Jaeho Chang, Phil F. Xie, Andrew Roth, Bob Amess, Hantao Lou, Katy J. McCann, Georgina Berridge, Roman Fischer, Chansavath Phetsouphanh, Ayo O. Omiyale, Brittany-Amber Jacobs, David Ahern, Simon R. Lord, Stewart Norris-Bulpitt, Sam T. Dobbie, Lucinda Griffiths, Kristen Aufiero Ramirez, Toni Ricciardi, Mary J. Macri, Aileen Ryan, Ralph R. Venhaus, Benoit J. Van den Eynde, Ioannis Karydis, Benedikt M. Kessler, Benjamin Schuster-Böckler, Mark R. Middleton, Xin Lu
Publikováno v:
Cancer Research. 82:1247-1247
For patients with inoperable esophageal adenocarcinoma (EAC), prognosis on conventional chemotherapy (CTX) remains poor. In 2021, the FDA approved two αPD-1 immune checkpoint inhibitors (ICI) for addition to fluoropyrimidine/platinum-containing CTX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76f5d2641b1d59ef3c689eb7850e59cf
https://doi.org/10.1158/1538-7445.am2022-1247
https://doi.org/10.1158/1538-7445.am2022-1247
Autor:
Shaun M. Flint, Rachel B Jones, Christopher J.E. Watson, Caroline O. S. Savage, Joseph A Chadwick, Nicholas Torpey, Don N Shanahan, Luke Devey, Ann-Marie O'Sullivan, Anna Richards, Robert B Henderson, Gemma D Banham, Paul A. Lyons, Kenneth G. C. Smith, Menna R. Clatworthy, Lars P. Erwig, Katie E Foster, Adele Gibson
Publikováno v:
The Lancet. 391:2619-2630
Summary Background B cells produce alloantibodies and activate alloreactive T cells, negatively affecting kidney transplant survival. By contrast, regulatory B cells are associated with transplant tolerance. Immunotherapies are needed that inhibit B-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015b18ea7152f91c02b34d06b770e3ec
https://doi.org/10.1016/s0140-6736(18)30984-x
https://doi.org/10.1016/s0140-6736(18)30984-x
Publikováno v:
Journal of Experimental Biology. 220:3976-3987
Despite the threat of climate change, the physiological mechanisms responsible for reduced performance at high temperatures remain unclear for most species. Elevated but sublethal temperatures may act via endocrine and cellular stress responses to li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ce06362f492ccb0d9209849e09a026
https://doi.org/10.1242/jeb.161224
https://doi.org/10.1242/jeb.161224
Publikováno v:
Conservation physiology. 3(1)
Climate change is predicted to change the distribution and abundance of species, yet underlying physiological mechanisms are complex and methods for detecting populations at risk from rising temperature are poorly developed. There is increasing inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2e2689fd315cba76df6f33f590a974
https://pubmed.ncbi.nlm.nih.gov/27293702
https://pubmed.ncbi.nlm.nih.gov/27293702
Autor:
Adele J. Wolfson, Lindsay Kua, Nicole E. Cyr, Joseph G. Chadwick, Lisa A. Bruce, Marc J. Tetel
Publikováno v:
Journal of Neuroendocrinology.
Thimet oligopeptidase (EC 3.4.24.15; also called EP24.15 and TOP; referred to here as TOP) is a neuropeptidase involved in the regulation of several physiological functions including reproduction. Among its substrates is gonadotrophin-releasing hormo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e040fc5b13a4743e4297fc448bef00
https://doi.org/10.1111/j.1365-2826.2010.02009.x
https://doi.org/10.1111/j.1365-2826.2010.02009.x
Autor:
Marc J. Tetel, Joseph G. Chadwick, Yingxin Zhao, Katherine L. Shea, Larry Denner, Heather A. Molenda-Figueira, Nora K. Siegal, Suzanne D. Murphy
In vitro studies reveal that nuclear receptor coactivators enhance the transcriptional activity of steroid receptors, including estrogen (ER) and progestin receptors (PR), through ligand-dependent interactions. Whereas work from our laboratory and ot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c490112d4eb2b772c2faf79a42f5ff02
https://europepmc.org/articles/PMC2582912/
https://europepmc.org/articles/PMC2582912/
Publikováno v:
Journal of Behavioral Medicine. 4:217-229
Psychological characteristics of 384 adult males classified as Type A or Type B by the structured interview were examined. Subjects classified Type A differed significantly from subjects classified Type B on a number of psychological scales including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6740525bc278a1ac9ee7e8c0084ca99
https://doi.org/10.1007/bf00844272
https://doi.org/10.1007/bf00844272
Autor:
Albert J. Morris, Joseph H. Chadwick
Publikováno v:
Transactions of the American Institute of Electrical Engineers. 70:346-350
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bbb27194920ba2dd32574d516a46089
https://doi.org/10.1109/t-aiee.1951.5060413
https://doi.org/10.1109/t-aiee.1951.5060413
Autor:
Shaw, Charles Gerard1 cgshaw@xtra.co.nz
Publikováno v:
Sex Education. May2023, Vol. 23 Issue 3, p271-278. 8p.