Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Joseph A. Callaway"'
Publikováno v:
Journal of Neurophysiology. 119:1745-1752
Oxytocin (OT) neurons exhibit larger afterhyperpolarizations (AHPs) following spike trains during late pregnancy and lactation, times when these neurons fire in bursts and release more OT associated with labor and lactation. Calcium-dependent AHPs me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73000fb6d1686bafaf0a8fa510869b20
https://doi.org/10.1152/jn.00608.2017
https://doi.org/10.1152/jn.00608.2017
Autor:
Lie Wang, Giri K Chandaka, Robert C. Foehring, William E. Armstrong, Matthew K. Kirchner, Joseph C. Callaway
Publikováno v:
The Journal of Physiology. 595:4927-4946
Key points Afterhyperpolarizations (AHPs) generated by repetitive action potentials in supraoptic magnocellular neurons regulate repetitive firing and spike frequency adaptation but relatively little is known about PIP2 's control of these AHPs. We e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30a5c5f549004a697085b5bf1e2b7ca3
https://doi.org/10.1113/jp274219
https://doi.org/10.1113/jp274219
Magnocellular oxytocin (OT) and vasopressin (VP) neurons express an afterhyperpolarization (AHP) following spike trains that attenuates firing rate and contributes to burst patterning. This AHP includes contributions from an apamin-sensitive, medium-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0875e497babfad8f29fb65e33928dd6
https://europepmc.org/articles/PMC6230773/
https://europepmc.org/articles/PMC6230773/
Autor:
Matthew K, Kirchner, Robert C, Foehring, Lie, Wang, Giri Kumar, Chandaka, Joseph C, Callaway, William E, Armstrong
Publikováno v:
The Journal of physiology. 595(14)
Afterhyperpolarizations (AHPs) generated by repetitive action potentials in supraoptic magnocellular neurons regulate repetitive firing and spike frequency adaptation but relatively little is known about PIP2’s control of these AHPs.We examined how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56219f16d6a6f5ecf095cc50028eb14d
https://pubmed.ncbi.nlm.nih.gov/28383826
https://pubmed.ncbi.nlm.nih.gov/28383826
Publikováno v:
Journal of Neurophysiology. 102:2326-2333
Dopamine (DA)-containing cells from the substantia nigra pars compacta (SNc) play a major role in the initiation of movement. Loss of these cells results in Parkinson's disease (PD). Changes in intracellular calcium ion concentration ([Ca2+]i) elicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::765102917b3be528a3c8b8a72336593e
https://doi.org/10.1152/jn.00038.2009
https://doi.org/10.1152/jn.00038.2009
Publikováno v:
Journal of Neurophysiology. 93:2012-2020
In neocortical pyramidal neurons, the medium (mAHP) and slow AHP (sAHP) have different relationships with intracellular [Ca2+]. To further explore these differences, we varied bath temperature and compared passive and active membrane properties and C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a229a7a4e70e57fc5fde61c8282092a0
https://doi.org/10.1152/jn.01017.2004
https://doi.org/10.1152/jn.01017.2004
Publikováno v:
Journal of Neuroscience Research. 77:82-89
Recent data indicate that molecular mimicry may play a role in the pathogenesis of human-T-lymphotropic virus type-1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP), an immune-mediated disease of the central nervous system (CNS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47468e49869e870b438e19de20ce53b
https://doi.org/10.1002/jnr.20137
https://doi.org/10.1002/jnr.20137
Publikováno v:
Journal of Computational Neuroscience. 15:367-389
We have constructed mathematical models of the electrical activity of two hypothalamic supraoptic neuro-secretory cell-types, and we support our models with new calcium imaging and in vitro electrophysiological data. These cells are neurones that pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f856cdb806c715c3a00c2ffb84afd51
https://doi.org/10.1023/a:1027424128972
https://doi.org/10.1023/a:1027424128972
Publikováno v:
Experimental Brain Research. 145:411-428
Our objective was to test the hypothesis that suppression of GABAergic inhibition results in an enhancement of responses to stimulation of the surround receptive field. Neurons in the forepaw barrel subfield (FBS) in rat first somatosensory cortex (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df2d9487b5f3f5ecb290d267c126b137
https://doi.org/10.1007/s00221-002-1124-7
https://doi.org/10.1007/s00221-002-1124-7
Autor:
Joseph C. Callaway, Karen A. Hasty, John M. Stuart, Franck Kalume, F. Curtis Dohan, Michael C. Levin, Sangmin Lee, Yvette Morcos, Joseph R. Zunt, Dominic M. Desiderio
Publikováno v:
Nature Medicine. 8:509-513
One hypothesis that couples infection with autoimmune disease is molecular mimicry. Molecular mimicry is characterized by an immune response to an environmental agent that cross-reacts with a host antigen, resulting in disease1,2. This hypothesis has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b86457f705451c31c03a3520fda74c
https://doi.org/10.1038/nm0502-509
https://doi.org/10.1038/nm0502-509