Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Joseph A. Buonomo"'
Publikováno v:
eLife, Vol 9 (2020)
Several virulence lipids populate the outer cell wall of pathogenic mycobacteria. Phthiocerol dimycocerosate (PDIM), one of the most abundant outer membrane lipids, plays important roles in both defending against host antimicrobial programs and in ev
Externí odkaz:
https://doaj.org/article/a662bef3e1b8482093eb39659e5a9059
Autor:
Tingting Dai, Jinghang Xie, Joseph A. Buonomo, Angel Moreno, Niaz Banaei, Carolyn R. Bertozzi, Jianghong Rao
Publikováno v:
Anal Chem
Increasingly difficult-to-treat infections by antibiotic-resistant bacteria have become a major public health challenge. Rapid detection of common resistance mechanisms before empiric antibiotic usage is essential for optimizing therapeutic outcomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c81f3dce1def4ddc85b7027e6026d40
https://europepmc.org/articles/PMC10175212/
https://europepmc.org/articles/PMC10175212/
Autor:
Scott I. Brody, Joseph A. Buonomo, Moyosore O. Orimoloye, Ziyi Jia, Sachin Sharma, Christopher D. Brown, Anthony D. Baughn, Courtney C. Aldrich
Publikováno v:
ChemBioChem. 24
Autor:
Malcolm S. Cole, Michael D. Howe, Joseph A. Buonomo, Sachin Sharma, Elise A. Lamont, Scott I. Brody, Neeraj K. Mishra, Yusuke Minato, Joshua M. Thiede, Anthony D. Baughn, Courtney C. Aldrich
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 28(51)
Tuberculosis (TB) is a leading source of infectious disease mortality globally. Antibiotic-resistant strains comprise an estimated 10 % of new TB cases and present an urgent need for novel therapeutics. β-lactam antibiotics have traditionally been i
Publikováno v:
Synthesis. 52:3583-3594
The recently reported chemoselective reduction of phosphine oxides with 1,3-diphenyldisiloxane (DPDS) has opened up the possibility of additive-free phosphine oxide reductions in catalytic systems. Herein we disclose the use of this new reducing agen
Autor:
Joseph A Buonomo
Publikováno v:
Chembiochem
In this viewpoint, the concepts that chemistry transcends the laboratory into the clinic and beyond is explored from the perspective of a single individual who began strictly within synthetic chemistry. They learned through their training that in rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebbed7b5f4bb6e800c535b85eef789cd
https://europepmc.org/articles/PMC8314862/
https://europepmc.org/articles/PMC8314862/
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Several virulence lipids populate the outer cell wall of pathogenic mycobacteria. Phthiocerol dimycocerosate (PDIM), one of the most abundant outer membrane lipids, plays important roles in both defending against host antimicrobial programs and in ev
Several virulence lipids populate the outer cell wall of pathogenic mycobacteria (Jackson, 2014). Phthiocerol dimycocerosate (PDIM), one of the most abundant outer membrane lipids (Anderson, 1929), plays important roles in both defending against host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::692cebf3e6dcd4f0caa669a79ab7185a
https://doi.org/10.1101/845081
https://doi.org/10.1101/845081
Autor:
Joseph A. Buonomo, Courtney C. Aldrich
Publikováno v:
Angewandte Chemie (International Ed. in English)
The Mitsunobu reaction is renowned for its mild reaction conditions and broad substrate tolerance, but has limited utility in process chemistry and industrial applications due to poor atom economy and the generation of stoichiometric phosphine oxide