Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Joseph A Piccirilli"'
Autor:
Sunita Maharjan, Howard Gamper, Yuka Yamaki, Thomas Christian, Robert Y. Henley, Nan-Sheng Li, Takeo Suzuki, Tsutomu Suzuki, Joseph A. Piccirilli, Meni Wanunu, Erin Seifert, Douglas C. Wallace, Ya-Ming Hou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Human mitochondrial tRNAs (mt-tRNAs), critical for mitochondrial biogenesis, are frequently associated with pathogenic mutations. These mt-tRNAs have unusual sequence motifs and require post-transcriptional modifications to stabilize their f
Externí odkaz:
https://doaj.org/article/6beaaf5507164908a32932465f77b163
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/d911c17efea44e6c824bb3f0a9f2da71
Publikováno v:
PLoS Biology, Vol 3, Iss 9, p e277 (2005)
The viability of living systems depends inextricably on enzymes that catalyze phosphoryl transfer reactions. For many enzymes in this class, including several ribozymes, divalent metal ions serve as obligate cofactors. Understanding how metal ions me
Externí odkaz:
https://doaj.org/article/32c5b5e5b9fe4905a5443f90ef0f96d1
Publikováno v:
ACS Omega, Vol 8, Iss 35, Pp 31941-31945 (2023)
Externí odkaz:
https://doaj.org/article/bccca0a743414b299e89c7b024051d5e
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. :1-14
Autor:
Benjamin Weissman, Şölen Ekesan, Hsuan-Chun Lin, Shahbaz Gardezi, Nan-Sheng Li, Timothy J. Giese, Erika McCarthy, Michael E. Harris, Darrin M. York, Joseph A. Piccirilli
Publikováno v:
Journal of the American Chemical Society. 145:2830-2839
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 42:538-546
Publikováno v:
Nature Methods. 19:576-585
High-resolution structural studies are essential for understanding the folding and function of diverse RNAs. Herein, we present a nanoarchitectural engineering strategy for efficient structural determination of RNA-only structures using single-partic
Autor:
Joseph A. Piccirilli, Ernst Lengyel, Brian B. Roman, Anthony A. Kossiakoff, Katja Gwin, Jean-Louis K. Kouadio, Anirban K. Mitra, Yilin Zhang, Karthik M. Sundaram
The supplemental file contains additional data from the analysis of the tissue microarray and additional experimental results related to conjugation, cell culture experiments, and animal imaging studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fc0082bf44ed537f38456d673090ad
https://doi.org/10.1158/0008-5472.22416801.v1
https://doi.org/10.1158/0008-5472.22416801.v1
Autor:
Joseph A. Piccirilli, Ernst Lengyel, Brian B. Roman, Anthony A. Kossiakoff, Katja Gwin, Jean-Louis K. Kouadio, Anirban K. Mitra, Yilin Zhang, Karthik M. Sundaram
Poor prognosis of ovarian cancer, the deadliest of the gynecologic malignancies, reflects major limitations associated with detection and diagnosis. Current methods lack high sensitivity to detect small tumors and high specificity to distinguish mali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574567be80468676318fc6886f0ca940
https://doi.org/10.1158/0008-5472.c.6509655.v1
https://doi.org/10.1158/0008-5472.c.6509655.v1