Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Joseph A Fontana"'
Autor:
Courtney M. Edwards, Jeremy F. Kane, Jailyn A. Smith, Déja M. Grant, Jasmine A. Johnson, Maria A. Hernandez Diaz, Lawrence A. Vecchi, Kai M. Bracey, Tolu N. Omokehinde, Joseph R. Fontana, Breelyn A. Karno, Halee T. Scott, Carolina J. Vogel, Jonathan W. Lowery, T. John Martin, Rachelle W. Johnson
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-17 (2024)
Abstract The role of parathyroid hormone (PTH)-related protein (PTHrP) in breast cancer remains controversial, with reports of PTHrP inhibiting or promoting primary tumor growth in preclinical studies. Here, we provide insight into these conflicting
Externí odkaz:
https://doaj.org/article/560f178405a849319bc2c5abf65d3d90
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e61015 (2013)
MicroRNAs have been implicated in many critical cellular processes including apoptosis. We have previously found that apoptosis in pancreatic cancer cells was induced by adamantyl retinoid-related (ARR) molecule 3-Cl-AHPC. Here we report that 3-Cl-AH
Externí odkaz:
https://doaj.org/article/10f671194ecc499bb40a9b2dff89678f
Autor:
Lawrence G. Lum, Elisabeth I. Heath, Joseph A. Fontana, Amanda Polend, Sarah Whitaker, Amy Schienschang, Dana Schalk, Brenda Dickow, Kimberlee Dobson, Meera Patel, Abhinav Deol, Wei Chen, Archana Thakur, Ulka N. Vaishampayan
A-C. FFPE sections of PC were stained by multiplex staining panel for CD4, CD8, FoxP3 (T regulatory cells), CD19 (B cells), CD68 (macrophages). Stained sections were imaged on the Hamamatsu slide scanner NanoZoomer S360 and images were viewed on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba11095d75504cd1e7c44648700c85f
https://doi.org/10.1158/1078-0432.22489167.v1
https://doi.org/10.1158/1078-0432.22489167.v1
Autor:
Lawrence G. Lum, Elisabeth I. Heath, Joseph A. Fontana, Amanda Polend, Sarah Whitaker, Amy Schienschang, Dana Schalk, Brenda Dickow, Kimberlee Dobson, Meera Patel, Abhinav Deol, Wei Chen, Archana Thakur, Ulka N. Vaishampayan
Purpose:A phase II study was conducted to evaluate the safety and efficacy of the combination of HER2 bispecific antibody (HER2Bi)-armed activated T cells (HER2 BAT) and programmed death 1 inhibitor, pembrolizumab.Patients and Methods:Patients with m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580063be1650d784214758a161da428b
https://doi.org/10.1158/1078-0432.c.6532896
https://doi.org/10.1158/1078-0432.c.6532896
Autor:
Lawrence G. Lum, Elisabeth I. Heath, Joseph A. Fontana, Amanda Polend, Sarah Whitaker, Amy Schienschang, Dana Schalk, Brenda Dickow, Kimberlee Dobson, Meera Patel, Abhinav Deol, Wei Chen, Archana Thakur, Ulka N. Vaishampayan
Representativeness of Study Participants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81cee5d6916b71e70b12c55cd8918002
https://doi.org/10.1158/1078-0432.22489164.v1
https://doi.org/10.1158/1078-0432.22489164.v1
Autor:
Anthony F. Shields, Joseph A. Fontana, Elisabeth I. Heath, Daryn W. Smith, Karri Stark, Julie Boerner, Kimberlee C. Dobson, Jawana M. Lawhorn-Crews, Lance K. Heilbrun, Izabela Podgorski, Ulka N. Vaishampayan
Purpose:Cabozantinib is a multitargeted tyrosine kinase inhibitor that demonstrated remarkable responses on bone scan in metastatic prostate cancer. Randomized trials failed to demonstrate statistically significant overall survival (OS). We studied t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5ac36e62fc75b4251d25ddeee8e8df
https://doi.org/10.1158/1078-0432.c.6529146
https://doi.org/10.1158/1078-0432.c.6529146
Supplementary Fig. S3 from SHP and Sin3A expression are essential for adamantyl-substituted retinoid-related molecule–mediated nuclear factor-κB activation, c-Fos/c-Jun expression, and cellular apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd78a7b2dfbf4ff59f8a25a0de3f8f2
https://doi.org/10.1158/1535-7163.22485140.v1
https://doi.org/10.1158/1535-7163.22485140.v1
Autor:
Anthony F. Shields, Joseph A. Fontana, Elisabeth I. Heath, Daryn W. Smith, Karri Stark, Julie Boerner, Kimberlee C. Dobson, Jawana M. Lawhorn-Crews, Lance K. Heilbrun, Izabela Podgorski, Ulka N. Vaishampayan
Table S1. Baseline patient characteristics Table S2 Rank Correlations of Percent Change in Imaging with Percent Change in Bone Markers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d3b7f9f2aa42f5c89a915b57a399520
https://doi.org/10.1158/1078-0432.22475685.v1
https://doi.org/10.1158/1078-0432.22475685.v1
We previously found that the adamantyl-substituted retinoid-related molecules bind to the small heterodimer partner (SHP) as well as the Sin3A complex. In this report, we delineated the role of SHP and the Sin3A complex in 4-[3′-(1-adamantyl)-4′-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665cc4eb41023b4af01faad038ac2e26
https://doi.org/10.1158/1535-7163.c.6531794.v1
https://doi.org/10.1158/1535-7163.c.6531794.v1
Autor:
Joseph A. Fontana, Zeben Xia, Gang Liu, David D. Moore, Li Wang, Mark Leid, Marcia I. Dawson, Lulu Farhana
Supplementary Figure 2 from Adamantyl-Substituted Retinoid-Related Molecules Bind Small Heterodimer Partner and Modulate the Sin3A Repressor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8074d5f8718b7d86abd7c07ca2df5d30
https://doi.org/10.1158/0008-5472.22366008
https://doi.org/10.1158/0008-5472.22366008