Zobrazeno 1 - 10
of 346
pro vyhledávání: '"Joseph A Adams"'
Autor:
Ryan R Cheng, Ellinor Haglund, Nicholas S Tiee, Faruck Morcos, Herbert Levine, Joseph A Adams, Patricia A Jennings, José N Onuchic
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201734 (2018)
Selecting amino acids to design novel protein-protein interactions that facilitate catalysis is a daunting challenge. We propose that a computational coevolutionary landscape based on sequence analysis alone offers a major advantage over expensive, t
Externí odkaz:
https://doaj.org/article/7dd888a3f09141b8a676ed9ee40d1100
Autor:
Hiruy S Meharena, Xiaorui Fan, Lalima G Ahuja, Malik M Keshwani, Christopher L McClendon, Angela M Chen, Joseph A Adams, Susan S Taylor
Publikováno v:
PLoS Biology, Vol 14, Iss 11, p e2000127 (2016)
Eukaryotic protein kinases regulate most cellular functions by phosphorylating targeted protein substrates through a highly conserved catalytic core. In the active state, the catalytic core oscillates between open, intermediate, and closed conformati
Externí odkaz:
https://doaj.org/article/a9ecdc8883d341479d40aa5acbc5baa1
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133801 (2015)
Externí odkaz:
https://doaj.org/article/febfcbe8c1fe42bc9389178b2abf6bf9
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127724 (2015)
The Src family of tyrosine kinases (SFKs) regulate numerous aspects of cell growth and differentiation and are under the principal control of the C-terminal Src Kinase (Csk). Although Csk and SFKs share conserved kinase, SH2 and SH3 domains, they dif
Externí odkaz:
https://doaj.org/article/f2d7a697c5cd4ff69d64605907f1bac5
Autor:
Sulyman Barkho, Levi C T Pierce, Maria L McGlone, Sheng Li, Virgil L Woods, Ross C Walker, Joseph A Adams, Patricia A Jennings
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 9, p e1003188 (2013)
The Src family of tyrosine kinases (SFKs) regulate numerous aspects of cell growth and differentiation and are under the principal control of the C-terminal Src Kinase (Csk). Csk and SFKs share a modular design with the kinase domain downstream of th
Externí odkaz:
https://doaj.org/article/bfbd58ccdb684fed88493358920fc89e
Autor:
Michael A Jamros, Leandro C Oliveira, Paul C Whitford, José N Onuchic, Joseph A Adams, Patricia A Jennings
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 9, p e1002695 (2012)
Protein kinases use ATP as a phosphoryl donor for the posttranslational modification of signaling targets. It is generally thought that the binding of this nucleotide induces conformational changes leading to closed, more compact forms of the kinase
Externí odkaz:
https://doaj.org/article/614cf3e9ac0a40b1bfcc192babbe9356
Autor:
Stephen J. Smith, Michael C. Witthoeft, Joseph S. Adams, Simon R. Bandler, Sophie Beaumont, James A. Chervenak, Renata S. Cumbee, Megan E. Eckart, Fred M. Finkbeiner, Sam V. Hull, Richard L. Kelley, Caroline A. Kilbourne, Maurice A. Leutenegger, Frederick S. Porter, Kazuhiro Sakai, Nicholas A. Wakeham, Edward J. Wassell
Publikováno v:
IEEE Transactions on Applied Superconductivity. 33:1-6
Autor:
Benjamin M. Adams, Joseph B. Adams, Reganne L. Brewster, Michael S. Cutler, Anthony E. Davis, Abby H. Gallegos, Jeremy S. Hernandez, Luke H. May, Emma G. Montoya, Andrew T. Reagan, Jack F. Shurley, Anna S. Grinath, Michael A. Thomas
Publikováno v:
Microbiology Resource Announcements. 11
Sara is a siphovirus with a linear 17,362bp genome containing 25 genes. Birdfeeder is a podovirus with a circularly permuted 53,897bp genome containing 52 genes. Sara and Birdfeeder were isolated from environmental samples in Plattsburgh, NY, USA and
Autor:
Malcolm Durkin, Caroline A. Kilbourne, E. V. Denison, Daniel S. Swetz, Fred M. Finkbeiner, James A. Chervenak, Richard L. Kelley, Stephen J. Smith, Ruslan Hummatov, Joseph W. Fowler, Kent D. Irwin, John E. Sadleir, Kazuhiro Sakai, Carl D. Reintsema, Maurice A. Leutenegger, Gene C. Hilton, Simon R. Bandler, Frederick S. Porter, Joseph S. Adams, M. C. Witthoeft, Leila R. Vale, Joel N. Ullom, Edward J. Wassell, Nicholas A. Wakeham, Sophie Beaumont, Antoine R. Miniussi, William B. Doriese
Publikováno v:
IEEE Transactions on Applied Superconductivity. 31:1-6
Future X-ray astrophysics experiments require multiplexed readout of high fill-factor, kilo-pixel arrays of transition-edge sensors (TESs), with very high spectral resolution over a broad range of energies. In this paper we report on a prototype kilo
Autor:
Brandon E. Aubol, Joseph A. Adams
Publikováno v:
The FEBS journalReferences. 289(23)
Serine-arginine protein kinase 1 (SRPK1) phosphorylates serine-arginine (SR) proteins in the cytoplasm, directing them to the nucleus for splicing function. SRPK1 has also been detected in the nucleus but its function here is still not fully understo