Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Joseph A, D'Alessio"'
Autor:
Joseph A. D'Alessio, Glenn Dranoff, Joel P. Wagner, Kimberly Aardalen, Tiancen Hu, David A. Ruddy, Tomas Rejtar, William R. Tschantz, Katherine Seiss, Katie Russo, Markus Vogel, Sabine Deutsch, Srinivas Chakravarthy, Rajiv Chopra, Brian Granda, Casey Landry, Alyssa Grantham, Si-Qi Liu
Table S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2ba7e7600f301da5f36ec6412b1e2a
https://doi.org/10.1158/2326-6066.22543066.v1
https://doi.org/10.1158/2326-6066.22543066.v1
Autor:
Joseph A. D'Alessio, Glenn Dranoff, Joel P. Wagner, Kimberly Aardalen, Tiancen Hu, David A. Ruddy, Tomas Rejtar, William R. Tschantz, Katherine Seiss, Katie Russo, Markus Vogel, Sabine Deutsch, Srinivas Chakravarthy, Rajiv Chopra, Brian Granda, Casey Landry, Alyssa Grantham, Si-Qi Liu
Supplementary Figures and Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87871a76cbc3aa1c923ef792d0181235
https://doi.org/10.1158/2326-6066.22543081.v1
https://doi.org/10.1158/2326-6066.22543081.v1
Autor:
Joseph A. D'Alessio, Glenn Dranoff, Joel P. Wagner, Kimberly Aardalen, Tiancen Hu, David A. Ruddy, Tomas Rejtar, William R. Tschantz, Katherine Seiss, Katie Russo, Markus Vogel, Sabine Deutsch, Srinivas Chakravarthy, Rajiv Chopra, Brian Granda, Casey Landry, Alyssa Grantham, Si-Qi Liu
CD3-bispecific antibodies represent an important therapeutic strategy in oncology. These molecules work by redirecting cytotoxic T cells to antigen-bearing tumor cells. Although CD3-bispecific antibodies have been developed for several clinical indic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c773deaaa2e2b6fd296bf63ecf07463f
https://doi.org/10.1158/2326-6066.c.6550126.v1
https://doi.org/10.1158/2326-6066.c.6550126.v1
Autor:
Tinya J. Abrams, Jason S. Damiano, Judith A. Abraham, Paul Kwon, Emma Lees, Nancy K. Pryer, Ursula Jeffry, Katherine G. Rendahl, Thomas Huber, Kathy Miller, Christie P. Fanton, Sylvie Lehmann, William R. Tschantz, GiNell Elliot, Rick Newcombe, Margaret E. McLaughlin, Jane Gu, Felipe C. Geyer, Majid Ghoddusi, Jean-Michel Rondeau, Keith G. Mansfield, Anu Connor, Chi Ying, Suzanna Clark, Angela Tam, Yan Tang, Christopher Karim, Daniel L. Menezes, Joseph A. D'Alessio, Qing Sheng
Figures S1, S2, s3, S4, Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657c2118ddc53bb94cc549cd76abf99c
https://doi.org/10.1158/1535-7163.22521895.v1
https://doi.org/10.1158/1535-7163.22521895.v1
Autor:
Tinya J. Abrams, Jason S. Damiano, Judith A. Abraham, Paul Kwon, Emma Lees, Nancy K. Pryer, Ursula Jeffry, Katherine G. Rendahl, Thomas Huber, Kathy Miller, Christie P. Fanton, Sylvie Lehmann, William R. Tschantz, GiNell Elliot, Rick Newcombe, Margaret E. McLaughlin, Jane Gu, Felipe C. Geyer, Majid Ghoddusi, Jean-Michel Rondeau, Keith G. Mansfield, Anu Connor, Chi Ying, Suzanna Clark, Angela Tam, Yan Tang, Christopher Karim, Daniel L. Menezes, Joseph A. D'Alessio, Qing Sheng
The cell surface glycoprotein P-cadherin is highly expressed in a number of malignancies, including those arising in the epithelium of the bladder, breast, esophagus, lung, and upper aerodigestive system. PCA062 is a P-cadherin specific antibody–dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42af133f07879ce825ff1f600618e03a
https://doi.org/10.1158/1535-7163.c.6543214.v1
https://doi.org/10.1158/1535-7163.c.6543214.v1
Autor:
Tinya J. Abrams, Jason S. Damiano, Judith A. Abraham, Paul Kwon, Emma Lees, Nancy K. Pryer, Ursula Jeffry, Katherine G. Rendahl, Thomas Huber, Kathy Miller, Christie P. Fanton, Sylvie Lehmann, William R. Tschantz, GiNell Elliot, Rick Newcombe, Margaret E. McLaughlin, Jane Gu, Felipe C. Geyer, Majid Ghoddusi, Jean-Michel Rondeau, Keith G. Mansfield, Anu Connor, Chi Ying, Suzanna Clark, Angela Tam, Yan Tang, Christopher Karim, Daniel L. Menezes, Joseph A. D'Alessio, Qing Sheng
Cell line sensitivity table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a00bb2e2018e033b09c776799bf3e3
https://doi.org/10.1158/1535-7163.22521889.v1
https://doi.org/10.1158/1535-7163.22521889.v1
Autor:
Matteo Duca, Darren Wan-Teck Lim, Vivek Subbiah, Shunji Takahashi, John Sarantopoulos, Andrea Varga, Joseph A. D'Alessio, Tinya Abrams, Qing Sheng, Eugene Youchin Tan, Maria Santos Rosa, Juan Gonzalez-Maffe, Janna Sand-Dejmek, Claire Fabre, Miguel Martin
Publikováno v:
Molecular Cancer Therapeutics. 21:625-634
This first-in-human (FIH), phase I, multicenter, open-label study was conducted to characterize the safety, tolerability, pharmacokinetics, and preliminary efficacy, and to establish the MTD/recommended dose for expansion (RDE) of PCA062 in patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291e623b5aa233a7b147ecce7e275a1d
https://doi.org/10.1158/1535-7163.mct-21-0652
https://doi.org/10.1158/1535-7163.mct-21-0652
Autor:
Tomas Rejtar, Markus Vogel, Srinivas Chakravarthy, Joseph Anthony D'alessio, Katie Russo, Alyssa Grantham, David A. Ruddy, Sabine Deutsch, Si-Qi Liu, Katherine Seiss, Tiancen Hu, William R. Tschantz, Glenn Dranoff, Casey Landry, Rajiv Chopra, Joel Wagner, Brian Granda, Kimberly Aardalen
Publikováno v:
Cancer Immunol Res
CD3-bispecific antibodies represent an important therapeutic strategy in oncology. These molecules work by redirecting cytotoxic T cells to antigen-bearing tumor cells. Although CD3-bispecific antibodies have been developed for several clinical indic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a176a8f79f4e3fa601fbb0ac0b7fd736
https://doi.org/10.1158/2326-6066.cir-20-0080
https://doi.org/10.1158/2326-6066.cir-20-0080
Autor:
Dominik Pistorius, Kathrin Buntin, Eric Weber, Etienne Richard, Caroline Bouquet, Séverine Wollbrett, Hugo Regenass, Victor Peón, Marcel Böhm, Régis Kessler, Thomas Gempeler, Anne Haberkorn, Laurin Wimmer, Christian Lanshoeft, John Davis, Dominik Hainzl, Joseph Anthony D'Alessio, Eusebio Manchado, Frank Petersen
Publikováno v:
Chemistry – A European Journal. 28
Access to the cyclic depsipeptide FR900359 (FR), a selective G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e153b268d60eac512cd14da130afc8a0
https://doi.org/10.1002/chem.202103888
https://doi.org/10.1002/chem.202103888
Autor:
Sindy Liao-Chan, Barbara Daine-Matsuoka, Nathan Heald, Tiffany Wong, Tracey Lin, Allen G Cai, Michelle Lai, Joseph A D'Alessio, Jan-Willem Theunissen
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124708 (2015)
Antibodies against cell surface antigens may be internalized through their specific interactions with these proteins and in some cases may induce or perturb antigen internalization. The anti-cancer efficacy of antibody-drug conjugates is thought to r
Externí odkaz:
https://doaj.org/article/36d07d62512441548835e2f6c9405095