Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Joseph, Salomone"'
Autor:
Kelsey H Elliott, Xiaoting Chen, Joseph Salomone, Praneet Chaturvedi, Preston A Schultz, Sai K Balchand, Jeffrey D Servetas, Aimée Zuniga, Rolf Zeller, Brian Gebelein, Matthew T Weirauch, Kevin A Peterson, Samantha A Brugmann
Publikováno v:
eLife, Vol 9 (2020)
Despite a common understanding that Gli TFs are utilized to convey a Hh morphogen gradient, genetic analyses suggest craniofacial development does not completely fit this paradigm. Using the mouse model (Mus musculus), we demonstrated that rather tha
Externí odkaz:
https://doaj.org/article/659f921a3e85487a949e94d7fb166cc9
Autor:
Yi Kuang, Ohad Golan, Kristina Preusse, Brittany Cain, Collin J Christensen, Joseph Salomone, Ian Campbell, FearGod V Okwubido-Williams, Matthew R Hass, Zhenyu Yuan, Nathanel Eafergan, Kenneth H Moberg, Rhett A Kovall, Raphael Kopan, David Sprinzak, Brian Gebelein
Publikováno v:
eLife, Vol 9 (2020)
Notch pathway haploinsufficiency can cause severe developmental syndromes with highly variable penetrance. Currently, we have a limited mechanistic understanding of phenotype variability due to gene dosage. Here, we unexpectedly found that inserting
Externí odkaz:
https://doaj.org/article/d503de51d4de46d4b3e298e0644a7d3d
Publikováno v:
Seminars in Cell & Developmental Biology.
Hox genes are a family of homeodomain transcription factors that regulate specialized morphological structures along the anterior-posterior axis of metazoans. Over the past few decades, researchers have focused on defining how Hox factors with simila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085fef2bcd5a004d58ff1d15f9c319bc
https://doi.org/10.1016/j.semcdb.2022.11.016
https://doi.org/10.1016/j.semcdb.2022.11.016
Autor:
Ángela del Águila, Mike Adam, Kristy Ullom, Nicholas Shaw, Shenyue Qin, Jacqueline Ehrman, Diana Nardini, Joseph Salomone, Brian Gebelein, Q. Richard Lu, Steven S. Potter, Ronald Waclaw, Kenneth Campbell, Masato Nakafuku
Publikováno v:
Development
Distinct neural stem cells (NSCs) reside in different regions of the subventricular zone (SVZ) and generate multiple olfactory bulb (OB) interneuron subtypes in the adult brain. However, the molecular mechanisms underlying such NSC heterogeneity rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3c118e026d1a51b1ada14104283639
https://europepmc.org/articles/PMC8959153/
https://europepmc.org/articles/PMC8959153/
Autor:
Kakajan Komurov, Brian Gebelein, Larry Sallans, Priyanka Arora, Jianqiang Wu, Matthew T. Weirauch, Frank B. Furnari, Sean E. Lawler, Nishtha Gupta, Angelo D'Alessandro, Gary A. Gudelsky, Biplab Dasgupta, Joseph Salomone, Kwangmin Choi, Nicole Oatman, Nupur Dasgupta, Sreeja Parameswaran, Cameron Brennan, Mruniya V. Gawali, Julie A. Reisz, Pankaj B. Desai
Publikováno v:
Science Advances
Genetic and epigenetic mechanisms determine SCD inhibitor sensitivity and acquired resistance through FOSB in cancer.
The lipogenic enzyme stearoyl CoA desaturase (SCD) plays a key role in tumor lipid metabolism and membrane architecture. SCD is
The lipogenic enzyme stearoyl CoA desaturase (SCD) plays a key role in tumor lipid metabolism and membrane architecture. SCD is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c018e974f1ef75e2f79a62c495b18425
https://doi.org/10.1126/sciadv.abd7459
https://doi.org/10.1126/sciadv.abd7459
Autor:
Praneet Chaturvedi, Matthew T. Weirauch, Sai K. Balchand, Kelsey H. Elliott, Kevin A. Peterson, Brian Gebelein, Aimée Zuniga, Samantha A. Brugmann, Rolf Zeller, Jeffrey D. Servetas, Joseph Salomone, Xiaoting Chen, Preston A. Schultz
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Despite a common understanding that Gli TFs are utilized to convey a Hh morphogen gradient, genetic analyses suggest craniofacial development does not completely fit this paradigm. Using the mouse model (Mus musculus), we demonstrated that rather tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ca66c61752a802fa24fbb4dbc30831
https://elifesciences.org/articles/56450
https://elifesciences.org/articles/56450
Autor:
Kelsey H Elliott, Xiaoting Chen, Joseph Salomone, Praneet Chaturvedi, Preston A Schultz, Sai K Balchand, Jeffrey D Servetas, Aimée Zuniga, Rolf Zeller, Brian Gebelein, Matthew T Weirauch, Kevin A Peterson, Samantha A Brugmann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5feaaab045492d8c24a8f21700587af
https://doi.org/10.7554/elife.56450.sa2
https://doi.org/10.7554/elife.56450.sa2
Autor:
Masato Nakafuku, Brian Gebelein, Kenneth Campbell, Hee-Woong Lim, Shenyue Qin, Temesgen D. Fufa, Bin Guan, Brittany Cain, Edward Farrow, Joseph Salomone, Robert B. Hufnagel
Publikováno v:
Genes Dev
How homeodomain proteins gain sufficient specificity to control different cell fates has been a long-standing problem in developmental biology. The conserved Gsx homeodomain proteins regulate specific aspects of neural development in animals from fli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b593f80c2db3d2f451274c1aa4b99b
https://pubmed.ncbi.nlm.nih.gov/33334823
https://pubmed.ncbi.nlm.nih.gov/33334823
Autor:
Brian Gebelein, Zhenyu Yuan, Yi Kuang, Raphael Kopan, Matthew R. Hass, FearGod V Okwubido-Williams, Ohad Golan, Kristina Preusse, Joseph Salomone, Collin J Christensen, Brittany Cain, Rhett A. Kovall, David Sprinzak, Ian Campbell, Kenneth H. Moberg, Nathanel Eafergan
Publikováno v:
eLife, Vol 9 (2020)
Notch pathway haploinsufficiency can cause severe developmental syndromes with highly variable penetrance. Currently, we have a limited mechanistic understanding of phenotype variability due to gene dosage. Here, we unexpectedly found that inserting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830b6f447d0e1bd3898e0fdaa1f85633
https://doi.org/10.7554/elife.53659
https://doi.org/10.7554/elife.53659
Autor:
Yi Kuang, Kristina Preusse, Matthew R. Hass, Ohad Golan, Ian Campbell, Zhenyu Yuan, David Sprinzak, Rhett A. Kovall, Raphael Kopan, Brittany Cain, Collin J Christensen, Brian Gebelein, Kenneth H. Moberg, FearGod V Okwubido-Williams, Nathanel Eafergan, Joseph Salomone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d808fd3b59b5e4b091bd358f10b40808
https://doi.org/10.7554/elife.53659.sa2
https://doi.org/10.7554/elife.53659.sa2