Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Joseph, Longworth"'
Autor:
Leticia Soriano-Baguet, Melanie Grusdat, Henry Kurniawan, Mohaned Benzarti, Carole Binsfeld, Anouk Ewen, Joseph Longworth, Lynn Bonetti, Luana Guerra, Davide G. Franchina, Takumi Kobayashi, Veronika Horkova, Charlène Verschueren, Sergio Helgueta, Deborah Gérard, Tushar H. More, Antonia Henne, Catherine Dostert, Sophie Farinelle, Antoine Lesur, Jean-Jacques Gérardy, Christian Jäger, Michel Mittelbronn, Lasse Sinkkonen, Karsten Hiller, Johannes Meiser, Dirk Brenner
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112153- (2023)
Summary: Pyruvate dehydrogenase (PDH) is the central enzyme connecting glycolysis and the tricarboxylic acid (TCA) cycle. The importance of PDH function in T helper 17 (Th17) cells still remains to be studied. Here, we show that PDH is essential for
Externí odkaz:
https://doaj.org/article/4c586aa5408c4295a1eead933ab65a54
Autor:
Joseph Longworth, Gunnar Dittmar
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100815- (2021)
Summary: The emergence of the coronavirus disease 2019 pandemic increased the interest in analysis of immunoglobulin responses. ELISA and lateral flow assays are widely used but are restricted by a single response value to an antigen or antigen pool.
Externí odkaz:
https://doaj.org/article/a4bcd274e37b4800bfbd13b11f4f51d6
Autor:
Vincent Gureghian, Hailee Herbst, Ines Kozar, Katarina Mihajlovic, Noël Malod-Dognin, Gaia Ceddia, Cristian Angeli, Christiane Margue, Tijana Randic, Demetra Philippidou, Milène Tetsi Nomigni, Ahmed Hemedan, Leon-Charles Tranchevent, Joseph Longworth, Mark Bauer, Apurva Badkas, Anthoula Gaigneaux, Arnaud Muller, Marek Ostaszewski, Fabrice Tolle, Nataša Pržulj, Stephanie Kreis
Therapy Induced Senescence (TIS) leads to sustained growth arrest of cancer cells. The associated cytostasis has been shown to be reversible and cells escaping senescence further enhance the aggressiveness of cancers. Together with targeted therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfc6e5557f14569079e2e1e54f858f28
https://doi.org/10.1101/2023.02.13.528114
https://doi.org/10.1101/2023.02.13.528114
Autor:
Gunnar Dittmar, Joseph Longworth
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100815-(2021)
STAR Protocols
STAR Protocols
The emergence of the Covid-19 pandemic increased the interest in analysis of immunoglobulin responses. ELISA and lateral flow assays are widely used, but are restricted by a single response value to an antigen or antigen pool. Here we describe antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c8586a798fae6a227f7517f7ecc4c5
http://www.sciencedirect.com/science/article/pii/S2666166721005219
http://www.sciencedirect.com/science/article/pii/S2666166721005219
Autor:
Sylvia Zerath Gurevich, Abhishek Sinha, Joseph Longworth, Rajesh K. Singh, Betsegaw E. Lemma, Anita Thakur, Oliver Popp, Daniel Kornitzer, Noa Reis, Martin Scheffner, Gunnar Dittmar, Elah Pick, David Fushman, Michael H. Glickman
Of all ubiquitin-like small protein modifiers, Rub1/NEDD8 is the closest kin of ubiquitin in sequence and in structure. Despite their profound similarities, prevalence of ubiquitin and of Rub1 is starkly different: targets of ubiquitin modification r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::547ea782573c4cca775c79ae3e238c58
https://doi.org/10.1101/2020.06.18.159145
https://doi.org/10.1101/2020.06.18.159145
Publikováno v:
Journal of Visualized Experiments.
Assessment of the global profile of ubiquitin chain topologies within a proteome is of interest to answer a wide range of biological questions. The protocol outlined here takes advantage of the di-glycine (-GG) modification left after the tryptic dig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f488112acaac9503443c0efa5b5646c
https://doi.org/10.3791/60702-v
https://doi.org/10.3791/60702-v
Autor:
Joseph, Longworth, Gunnar, Dittmar
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1977
Protein homeostasis is essential for the survival of cells. It is closely related to the functioning of the ubiquitin-proteasome system, which utilizes the small protein ubiquitin as a posttranslational modifier (PTM). Clinically, the modification is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da6cdf187c503018f87e2b1aa854709e
https://pubmed.ncbi.nlm.nih.gov/30980320
https://pubmed.ncbi.nlm.nih.gov/30980320
Autor:
Christian Behl, Christian Haass, Petra Goldmann, Nikolas Furthmann, Jens Meschede, Konstanze F. Winklhofer, Alina Blusch, Dietrich Trümbach, Kohji Mori, Mark S. Hipp, Cathrin Schnack, Wolfgang Wurst, Verian Bader, Jörg Tatzelt, Joseph Longworth, Cathrin Showkat, Elisabeth Petrasch-Parwez, Maria Patra, Carsten Saft, Thomas Arzberger, Dominik A. Sehr, Albrecht M. Clement, Lena A. Berlemann, Lena Angersbach, F. Ulrich Hartl, Ana Sánchez-Vicente, Andreas C. Woerner, Gisa Ellrichmann, Eva M van Well, Ralf Gold, Gunnar Dittmar
Publikováno v:
The EMBO journal 38(9), e100730 (2019). doi:10.15252/embj.2018100730
Neurodegenerative diseases are characterized by the accumulation of misfolded proteins in the brain. Insights into protein quality control mechanisms to prevent neuronal dysfunction and cell death are crucial in developing causal therapies. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9026497cb3304040f80c960a7bcdd512
https://pub.dzne.de/record/140707
https://pub.dzne.de/record/140707
Autor:
Gunnar Dittmar, Joseph Longworth
Publikováno v:
Methods in Molecular Biology ISBN: 9781493992317
Protein homeostasis is essential for the survival of cells. It is closely related to the functioning of the ubiquitin-proteasome system, which utilizes the small protein ubiquitin as a posttranslational modifier (PTM). Clinically, the modification is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::862a865b3947c68610033e7941f1b03a
https://doi.org/10.1007/978-1-4939-9232-4_3
https://doi.org/10.1007/978-1-4939-9232-4_3
Autor:
Freddy Bunbury, Phillip C. Wright, David A. Russo, Katherine E. Helliwell, Matthew B Cooper, Ulrich Johan Kudahl, Joseph Longworth, Eleanor V. Tomsett, Jagroop Pandhal, Deborah L. Salmon, Nicholas Smirnoff, Alison G. Smith
Publikováno v:
The New Phytologist
Summary The unicellular green alga Lobomonas rostrata requires an external supply of vitamin B12 (cobalamin) for growth, which it can obtain in stable laboratory cultures from the soil bacterium Mesorhizobium loti in exchange for photosynthate. We in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d6634a6ec993dca5f9efd6b78fdc4f