Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Joseph, Kwentus"'
Autor:
Suleyman Gulsuner, Tom Walsh, Amanda C. Watts, Ming K. Lee, Anne M. Thornton, Silvia Casadei, Caitlin Rippey, Hashem Shahin, Vishwajit L. Nimgaonkar, Rodney C.P. Go, Robert M. Savage, Neal R. Swerdlow, Raquel E. Gur, David L. Braff, Mary-Claire King, Jon M. McClellan, David Braff, Kristin S. Cadenhead, Monica E. Calkins, Dorcas J. Dobie, Robert Freedman, Michael Green, Tiffany Greenwood, Ruben C. Gur, Laura Lazzeroni, Gregory Light, Keith Nuechterlein, Ann Olincy, Al Radant, Amrita Ray, Nik Schork, Larry J. Seidman, Larry Siever, Jeremy Silverman, William S. Stone, Catherine Sugar, Neal Swerdlow, Debby Tsuang, Ming Tsuang, Bruce Turetsky, Tolulope Aduroja, Trina Allen, L. Diane Bradford, Bernie Devlin, Neil B. Edwards, Rohan Ganguli, Joseph Kwentus, Adrienne C. Lahti, Paul Lyons, Kim Mathos, Roberta May, Steve McLeod-Bryant, Joseph P. McEvoy, Laura Montgomery-Barefield, Judith O’Jile, Al Santos, Charles L. Swanson, William Wilson
Publikováno v:
Cell. 154:518-529
SummaryGenes disrupted in schizophrenia may be revealed by de novo mutations in affected persons from otherwise healthy families. Furthermore, during normal brain development, genes are expressed in patterns specific to developmental stage and neuroa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6b6e7138d7338531a9411bfa3e6f10
https://doi.org/10.1016/j.cell.2013.06.049
https://doi.org/10.1016/j.cell.2013.06.049
Autor:
Joseph Kwentus, Mikhil Bamne, Annie M. Watson, Rodney T. Perry, Lambertus Klei, Trina B. Allen, Alberto B. Santos, Joseph P. McEvoy, Henry A. Nasrallah, B. Devlin, Cemil Çelik, L. DiAnne Bradford, Raquel E. Gur, Joel Wood, Hader Mansour, Robert Savage, Neil B. Edwards, Monica E. Calkins, Rodney C.P. Go, Robert H. Yolken, Vishwajit L. Nimgaonkar, Ruben C. Gur, Kodavali V. Chowdari
Publikováno v:
Schizophrenia Bulletin. 38:1149-1154
Background: Genome-wide association studies (GWAS) implicate single nucleotide polymorphisms (SNPs) on chromosome 6p21.3-22.1, the human leukocyte antigen (HLA) region, as common risk factors for schizophrenia (SZ). Other studies implicate viral and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7f7a0931942e9de756f720dce8eebd
https://doi.org/10.1093/schbul/sbs087
https://doi.org/10.1093/schbul/sbs087
Autor:
Neil B. Edwards, L. D. Bradford, Bernie Devlin, Raquel E. Gur, Adrienne C. Lahti, Judith Rosemary O'Jile, Alberto B. Santos, Henry A. Nasrallah, Joseph P. McEvoy, Vishwajit L. Nimgaonkar, Monica E. Calkins, Roberta S. May, Trina B. Allen, Howard W. Wiener, Joseph Kwentus, T. Aduroja, Rodney C.P. Go, L. Montgomery-Barefield, Robert Savage
Publikováno v:
Schizophrenia Research. 139:105-109
The role of daily functioning is an integral part of the schizophrenia (SZ) phenotype and deficits in this trait appear to be present in both affected persons and some unaffected relatives; hence we have examined its heritability in our cohort of Afr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0b26dd84f4d848efb98f8d82fbd75b
https://doi.org/10.1016/j.schres.2012.04.015
https://doi.org/10.1016/j.schres.2012.04.015
Autor:
Morteza Marandi, Robert S. Fishman, Joseph Kwentus, Michael H. Allen, Daniel A. Spyker, James V. Cassella, Raymond A Manning, John H. Kehne, Robert A. Riesenberg
Publikováno v:
Bipolar Disorders. 14:31-40
Kwentus J, Riesenberg RA, Marandi M, Manning RA, Allen MH, Fishman RS, Spyker DA, Kehne JH, Cassella JV. Rapid acute treatment of agitation in patients with bipolar I disorder: a multicenter, randomized, placebo-controlled clinical trial with inhaled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::526eb3fda319745ea6d62a611c497d81
https://doi.org/10.1111/j.1399-5618.2011.00975.x
https://doi.org/10.1111/j.1399-5618.2011.00975.x
Autor:
Raquel E. Gur, Vishwajit L. Nimgaonkar, Neil B. Edwards, Rodney C.P. Go, Alberto B. Santos, Robert Savage, Bernie Devlin, Trina B. Allen, Howard W. Wiener, Joseph P. McEvoy, Ruben C. Gur, Jan Richard, Joseph Kwentus, L. DiAnne Bradford, Lambertus Klei, Monica E. Calkins, Joel Wood
Publikováno v:
Schizophrenia Bulletin
Objective: Various measures of neurocognitive function show mean differences among individuals with schizophrenia (SZ), their relatives, and population controls. We use eigenvector transformations that maximize heritability of multiple neurocognitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11e67dba913541daa8660f2d810be93
https://doi.org/10.1093/schbul/sbr161
https://doi.org/10.1093/schbul/sbr161
Autor:
Joseph Kwentus, Raquel E. Gur, Trina B. Allen, L. DiAnne Bradford, Howard W. Wiener, J. Daniel Ragland, Judith Rosemary O'Jile, Bernie Devlin, Lambertus Klei, Alberto B. Santos, Ping Tepper, Vishwajit L. Nimgaonkar, Paul D. Lyons, Rodney C.P. Go, Monica E. Calkins, Neil B. Edwards, Robert Savage, Muktar H. Aliyu, Jan Richard, Ruben C. Gur
Publikováno v:
American Journal of Psychiatry. 167:459-472
Neurocognitive impairments in schizophrenia are well replicated and widely regarded as candidate endophenotypes that may facilitate understanding of schizophrenia genetics and pathophysiology. The Project Among African-Americans to Explore Risks for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::face767c7a689551443d31c084f44327
https://doi.org/10.1176/appi.ajp.2009.08091351
https://doi.org/10.1176/appi.ajp.2009.08091351
Autor:
Michael John Owen, L. Di Anne Bradford, Rodney C.P. Go, Neil B. Edwards, Lora McClain, Bernie Devlin, Raquel E. Gur, Ruben C. Gur, Robert Savage, Monica E. Calkins, Joseph P. McEvoy, Michael Conlon O'Donovan, Judith Rosemary O'Jile, Michael E. Talkowski, Draga Toncheva, Hader Mansour, Gerard Vockley, Lyudmila Georgieva, Trina B. Allen, Paul D. Lyons, Kodavali V. Chowdari, Alberto B. Santos, Joseph Kwentus, George Kirov, Joel Wood, Vishwajit L. Nimgaonkar
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :560-569
Recessive mutations in the phenylalanine hydroxylase (PAH) gene predispose to phenylketonuria (PKU) in conjunction with dietary exposure to phenylalanine. Previous studies have suggested PAH variations could confer risk for schizophrenia, but compreh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d973f48fefc670457901e22357ee05b
https://doi.org/10.1002/ajmg.b.30862
https://doi.org/10.1002/ajmg.b.30862
Autor:
Muktar H, Aliyu, Monica E, Calkins, Charlie L, Swanson, Paul D, Lyons, Robert M, Savage, Roberta, May, Howard, Wiener, Stephen, McLeod-Bryant, Bernie, Devlin, Vishwajit L, Nimgaonkar, J Daniel, Ragland, Raquel E, Gur, Ruben C, Gur, L Dianne, Bradford, Neil, Edwards, Joseph, Kwentus, Joseph P, McEvoy, Alberto B, Santos, Stephen, McCleod-Bryant, Clifton, Tennison, Rodney C P, Go, Trina B, Allen
Publikováno v:
Schizophrenia Research. 87:32-44
The Project among African-Americans to Explore Risks for Schizophrenia (PAARTNERS) is a multi-site, NIMH-funded study that seeks to identify genetic polymorphisms that confer susceptibility to schizophrenia among African-Americans by linkage mapping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1c75d1c581febaf924a0b99212df74
https://doi.org/10.1016/j.schres.2006.06.027
https://doi.org/10.1016/j.schres.2006.06.027
Autor:
Dennis E. Schmidt, John F Gouda, Benjamin W. Johnson, Richard Shiavi, Joseph Kwentus, John S. Kennedy, Ronald M. Salomon, Jennifer Urbano Blackford, Harry E. Gwirtsman
Publikováno v:
Neuropsychopharmacology. 30:2082-2091
Unipolar and bipolar depressions show abnormal behavioral manifestations of ultradian (less than 24 h) rhythms, but abnormal rhythms of the central neurotransmitters thought to be important for depression pathophysiology (eg dopamine (DA) and seroton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a14a74c9770d551ace77097f08c9912a
https://doi.org/10.1038/sj.npp.1300746
https://doi.org/10.1038/sj.npp.1300746
Central Nervous System disorders have an enormous impact on individuals and on society as a whole. The development of better treatments is crucial and is a major focus of pharmaceutical and biotechnology companies. This book explains the complicated
