Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Joseph, Clayton"'
Autor:
Mohamed Ibrahim, Xinyuanyuan Sun, Vinicius Martins de Oliveira, Ruibin Liu, Joseph Clayton, Haifa El Kilani, Jana Shen, Rolf Hilgenfeld
Publikováno v:
hLife, Vol 2, Iss 8, Pp 419-433 (2024)
During the continuing evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the Omicron variant of concern emerged in the second half of 2021 and has been dominant since November of that year. Along with its sublineages, it has m
Externí odkaz:
https://doaj.org/article/267a1214c0c245738d97eb6061005e8c
Publikováno v:
JACS Au, Vol 4, Iss 4, Pp 1374-1384 (2024)
Externí odkaz:
https://doaj.org/article/4d0c7ff9b9b64f46a70b3c749b23cb5a
Autor:
McReynolds, Joseph Clayton
Publikováno v:
Dickens Studies Annual: Essays on Victorian Fiction, 2020 Mar 01. 51(1), 20-39.
Externí odkaz:
https://www.jstor.org/stable/10.5325/dickstudannu.51.1.0020
Publikováno v:
J Chem Inf Model
The ERK pathway is one of the most important signaling cascades involved in tumorigenesis. So far, eight noncovalent inhibitors of RAF and MEK kinases in the ERK pathway have been approved by the FDA for treatment of cancers; however, their efficacie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942edf0a40a3f060062cde728bde9135
https://doi.org/10.1021/acs.jcim.3c00014
https://doi.org/10.1021/acs.jcim.3c00014
Autor:
Joseph Clayton, Vinícius Martins de Oliveira, Mohamed Fouad Ibrahim, Xinyuanyuan Sun, Paween Mahinthichaichan, Mingzhe Shen, Rolf Hilgenfeld, Jana Shen
Publikováno v:
Journal of Chemical Information and Modeling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdf01626351ddb3ae4c313f5baf2de7e
https://doi.org/10.1021/acs.jcim.3c00344
https://doi.org/10.1021/acs.jcim.3c00344
Autor:
Efemena Michael Diejomaoh MD, Joseph Clayton Gathe MD, FACP, FIDSA, Carl Craig Mayberry PA-C, John Benjamin Clemmons MD, Bernie Miguel MD, Alan Glombicki MD, Benjamin Daquioag MD
Publikováno v:
Journal of the International Association of Providers of AIDS Care, Vol 16 (2017)
Registrational studies and observational cohorts clearly suggest sustained virologic response (SVR) rates in HIV-/hepatitis C–coinfected patients are similar to monoinfected patients when utilizing interferon-free regimens, and this can be accompli
Externí odkaz:
https://doaj.org/article/4d0c2458b3c345699c4e8563f040f458
Autor:
Joel A. Aronowitz, Daniel Oheb, Nathan Cai, Asli Pekcan, Bridget Winterhalter, Joseph Clayton
Publikováno v:
Regenerative Medicine ISBN: 9783030755164
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42229fe19b2f1f17b875b77654abfd41
https://doi.org/10.1007/978-3-030-75517-1_26
https://doi.org/10.1007/978-3-030-75517-1_26
Autor:
Rongze Yang, Shuyan Han, Joseph Clayton, Mahan Haghighatian, Cheng-Chieh Tsai, Yuan Yao, Pingping Li, Jana Shen, Qun Zhou
Publikováno v:
Cancers; Volume 14; Issue 15; Pages: 3763
Triple-negative breast cancer (TNBC) cells reprogram their metabolism to provide metabolic flexibility for tumor cell growth and survival in the tumor microenvironment. While our previous findings indicated that endothelial lipase (EL/LIPG) is a hall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9345b5eb9e1a5cf5d6e4ed891895fcf7
Autor:
Joseph Clayton, Vinicius Martins de Oliveira, Mohamed Fouad Ibraham, Xinyuanyuan Sun, Paween Mahinthichaichan, Mingzhe Shen, Rolf Hilgenfeld, Jana Shen
Nirmatrelvir is an orally available inhibitor of SARS-CoV-2 main protease (Mpro) and the main ingredient of PAXLOVID, a drug approved by FDA for high-risk COVID-19 patients. Recently, a rare natural mutation, H172Y, was found to significantly reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecb9c5be606d3c460517d16d35872bf1
https://doi.org/10.1101/2022.07.31.502215
https://doi.org/10.1101/2022.07.31.502215
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618547
Methods Mol Biol
Methods Mol Biol
Molecular dynamics simulations can in theory reveal the thermodynamics and kinetics of peptide conformational transitions at atomic-level resolution. However, even with modern computing power, they are limited in the timescales they can sample, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c532aadb1028844febc1d065b7cac7
https://doi.org/10.1007/978-1-0716-1855-4_8
https://doi.org/10.1007/978-1-0716-1855-4_8