Lower respiratory tract infections in children requiring mechanical ventilation: a multicentre prospective surveillance study incorporating airway metagenomics

Autor: Alexandra Tsitsiklis, PhD, Christina M Osborne, MD, Jack Kamm, PhD, Kayla Williamson, MS, Katrina Kalantar, PhD, Gytis Dudas, PhD, Saharai Caldera, BA, Amy Lyden, BA, Michelle Tan, BS, Norma Neff, PhD, Victoria Soesanto, BS, J Kirk Harris, PhD, Lilliam Ambroggio, PhD, Aline B Maddux, MD, Todd C Carpenter, MD, Ron W Reeder, PhD, Chris Locandro, MS, Eric A F Simões, ProfMD, Matthew K Leroue, MD, Mark W Hall, ProfMD, Athena F Zuppa, ProfMD, Joseph Carcillo, ProfMD, Kathleen L Meert, ProfMD, Anil Sapru, ProfMD, Murray M Pollack, ProfMD, Patrick S McQuillen, ProfMD, Daniel A Notterman, ProfMD, J Michael Dean, ProfMD, Matt S Zinter, MD, Brandie D Wagner, PhD, Joseph L DeRisi, ProfPhD, Peter M Mourani, ProfMD, Charles R Langelier, MDPhD

Publikováno v: The Lancet Microbe, Vol 3, Iss 4, Pp e284-e293 (2022)

Summary: Background: Lower respiratory tract infections (LRTI) are a leading cause of critical illness and mortality in mechanically ventilated children; however, the pathogenic microbes frequently remain unknown. We combined traditional diagnostics

Externí odkaz: https://doaj.org/article/bf9afb105f554ba7841ff015408ec805

Risk Factors for Mortality in Refractory Pediatric Septic Shock Supported with Extracorporeal Life Support

Autor: Heidi J. Dalton, Rick Harrison, David K. Bailly, David L. Wessel, Murray M Pollack, Joseph Carcillo, J. Michael Dean, Thomas P. Shanley, Robert A. Berg, Kathleen L Meert, Jennifer K. Workman, Ron W Reeder, Christopher J. L. Newth

Publikováno v: ASAIO J

Risk factors for mortality in children with refractory pediatric septic shock who are supported with extracorporeal life support (ECLS) are largely unknown. Therefore, we performed univariable and multivariable analyses to determine risk factors for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a82739ed26409f8e33dc3a2ec9585e1
https://doi.org/10.1097/mat.0000000000001147

Assessment of Positive Predictive Value of the IPSO Definitions at a Quaternary Hospital

Autor: Daniel Loeb, Johanna Rosen, Vikram Raghu, Adrienne Marcinick, Gabriella Butler, Joseph Carcillo, Christopher M. Horvat

Publikováno v: Pediatric Quality & Safety

The Children’s Hospital Association’s Improving Pediatric Sepsis Outcomes (IPSO) collaborative is a multi-center quality improvement (QI) learning collaborative of 61 U.S. children’s hospitals that seeks to improve sepsis outcomes through colla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412f00d3245ee5c9911d856937e06b5f
http://europepmc.org/articles/PMC8686814

Lower respiratory tract infections in children requiring mechanical ventilation: a multicentre prospective surveillance study incorporating airway metagenomics

Autor: Alexandra Tsitsiklis, Christina M Osborne, Jack Kamm, Kayla Williamson, Katrina Kalantar, Gytis Dudas, Saharai Caldera, Amy Lyden, Michelle Tan, Norma Neff, Victoria Soesanto, J Kirk Harris, Lilliam Ambroggio, Aline B Maddux, Todd C Carpenter, Ron W Reeder, Chris Locandro, Eric A F Simões, Matthew K Leroue, Mark W Hall, Athena F Zuppa, Joseph Carcillo, Kathleen L Meert, Anil Sapru, Murray M Pollack, Patrick S McQuillen, Daniel A Notterman, J Michael Dean, Matt S Zinter, Brandie D Wagner, Joseph L DeRisi, Peter M Mourani, Charles R Langelier

Publikováno v: The Lancet. Microbe, vol 3, iss 4

BackgroundLower respiratory tract infections (LRTI) are a leading cause of critical illness and mortality in mechanically ventilated children; however, the pathogenic microbes frequently remain unknown. We combined traditional diagnostics with metage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17488386893d346faeb9fffb9a8240bf
https://pubmed.ncbi.nlm.nih.gov/35544065

Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children

Autor: Robert C. Tasker, David Inwald, Judy T. Verger, Andrea T. Cruz, Christopher J. L. Newth, Christopher L. Carroll, Enitan D. Carrol, Mark E. Nunnally, Margaret M. Parker, Joseph Carcillo, Lyvonne N Tume, Akira Nishisaki, Daniele De Luca, Lewis H. Romer, Claudio Flauzino De Oliveira, Koen F. M. Joosten, Trung C. Nguyen, Joris Lemson, Raina Paul, Joshua Wolf, Hector R. Wong, Etienne Javouhey, Simon Nadel, Suchitra Ranjit, Mark J. Peters, Graeme MacLaren, Niranjan Kissoon, Halden F. Scott, Karen Choong, Jerry J. Zimmerman, Oliver Karam, Saul N. Faust, Waleed Alhazzani, Morten Hylander Møller, Nilesh M. Mehta, Poonam Joshi, Luregn J. Schlapbach, Akash Deep, Andrew C. Argent, Michael S. D. Agus, Ira M. Cheifetz, Heidi R. Flori, Jeffry J. Cies, Martin C. J. Kneyber, Scott L. Weiss, Adrienne G. Randolph, Joe Brierley, Mark W. Hall, Paul Ishimine, Pierre Tissieres, Eric A. Williams

Publikováno v: Pediatric Critical Care Medicine, 21, 186-195
Intensive Care Medicine, 46, Suppl 1, pp. 1-9
Pediatric Critical Care Medicine, 21, 2, pp. 186-195
Intensive Care Medicine, 46(SUPPL 1), 1-9. Springer-Verlag
Intensive Care Medicine
Intensive Care Medicine, Springer Verlag, 2020, 46 (Suppl 1), pp.1--9. ⟨10.1007/s00134-019-05877-7⟩
Pediatric Critical Care Medicine: A Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Pediatric Critical Care Medicine: A Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2020, 21 (2), pp.186--195. ⟨10.1097/PCC.0000000000002197⟩
Pediatric Critical Care Medicine, 21(2), 186-195. Lippincott Williams & Wilkins
Intensive Care Medicine, 2020, 46 (Suppl 1), pp.1--9. ⟨10.1007/s00134-019-05877-7⟩
Intensive Care Medicine, 46, 1-9

In 2001, the Surviving Sepsis Campaign (SSC) began to develop evidence-based guidelines and recommendations for the resuscitation and management of patients with sepsis. With the 2016 edition, the Society of Critical Care Medicine and European Societ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83de2a9c24700ab4e3b9fbaf798a94e4
http://hdl.handle.net/2066/220773