Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Joseph, Boothe"'
Autor:
Steve Zaplachinski, Joseph Boothe, John Teat, J. Christopher Hall, Rongji Chen, Haifeng Wang, Michael D. McLean, Deqiang Yu, Kor-Zheng Mah
Publikováno v:
Transgenic Research. 21:1291-1301
Production of therapeutic monoclonal antibodies using genetically modified plants may provide low cost, high scalability and product safety; however, antibody purification from plants presents a challenge due to the large quantities of biomass that n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d2101e8d7d9c8a18a726ab6ecee7c6
https://doi.org/10.1007/s11248-012-9603-5
https://doi.org/10.1007/s11248-012-9603-5
Autor:
Maurice M. Moloney, Jean-Claude Tardif, Elizabeth Wanda Murray, Reid Alexandra, David Busseuil, Cory Nykiforuk, Joseph Boothe, Yin Shen, Eric Rhéaume
Publikováno v:
Plant Biotechnology Journal. 9:250-263
Apolipoprotein AI Milano (ApoAI(Milano) ) was expressed as a fusion protein in transgenic safflower seeds. High levels of expression corresponding to 7 g of ApoAI(Milano) per kilogram of seed have been identified in a line selected for commercializat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c74e0a79c93e6825b2df6c7c7384907
https://doi.org/10.1111/j.1467-7652.2010.00546.x
https://doi.org/10.1111/j.1467-7652.2010.00546.x
Autor:
Steven Szarka, Steven Zaplachinski, Maurice M. Moloney, Cory Nykiforuk, Douglas W. Morck, Joseph Boothe, Elizabeth Wanda Murray, Yin Shen, Philip A. Kuhlman
Publikováno v:
Plant Biotechnology Journal. 8:588-606
The evolution of the seed system provides enormous adaptability to the gymnosperms and angiosperms, because of the properties of dormancy, nutrient storage and seedling vigour. Many of the unique properties of seeds can be exploited in molecular farm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e6ed4191c22f2483e878cf5f66bd3d9
https://doi.org/10.1111/j.1467-7652.2010.00511.x
https://doi.org/10.1111/j.1467-7652.2010.00511.x
Publikováno v:
Scopus-Elsevier
Expression of recombinant proteins as translational fusions is commonly employed to enhance stability, increase solubility and facilitate purification of the desired protein. In general, such fusion proteins must be cleaved to release the mature prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d2d576fdf92ab7318c3d73dff5d19e
https://doi.org/10.1093/protein/gzg091
https://doi.org/10.1093/protein/gzg091
Publikováno v:
Drug Development Research. 42:172-181
The advantages and limitations of plant-based systems for the production of recombinant biopharmaceutical proteins are discussed in the context of other host production systems presently available. A novel approach for the purification of recombinant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f993118772212304edcfdd9990e6fff
https://doi.org/10.1002/(sici)1098-2299(199711/12)42:3/4<172::aid-ddr9>3.0.co
https://doi.org/10.1002/(sici)1098-2299(199711/12)42:3/4<172::aid-ddr9>3.0.co
Plant-Derived Manufacturing of Apolipoprotein AIMilano: Purification and Functional Characterization
Publikováno v:
Production of Plasma Proteins for Therapeutic Use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::708dc055fa3d3cb7f7210eb2ef7c4040
https://doi.org/10.1002/9781118356807.ch20
https://doi.org/10.1002/9781118356807.ch20
Autor:
Joseph Boothe, Cory Nykiforuk
Publikováno v:
Methods in Molecular Biology ISBN: 9781617799204
The production of therapeutic proteins in plant seed augments alternative production platforms such as microbial fermentation, cell-based systems, transgenic animals, and other recombinant plant production systems to meet increasing demands for the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fac524fa695f1576d7e345ae856c111
https://doi.org/10.1007/978-1-61779-921-1_16
https://doi.org/10.1007/978-1-61779-921-1_16
Autor:
Steve Zaplachinski, Mei Zhang, Olga Petrivna Yurchenko, Ana Fidantsef, Catherine Reed, Maurice M. Moloney, Joseph Boothe, Cory Nykiforuk, Christine Shewmaker, Gunamani S. Oinam, Indra Harry
Publikováno v:
Transgenic research. 21(2)
Gamma linolenic acid (GLA; C18:3Δ6,9,12 cis), also known as γ-Linolenic acid, is an important essential fatty acid precursor for the synthesis of very long chain polyunsaturated fatty acids and important pathways involved in human health. GLA is sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ade5c73fadc5f49e7d49ff84b825474
https://pubmed.ncbi.nlm.nih.gov/21853296
https://pubmed.ncbi.nlm.nih.gov/21853296
Autor:
Joseph, Boothe, Cory, Nykiforuk, Yin, Shen, Steven, Zaplachinski, Steven, Szarka, Philip, Kuhlman, Elizabeth, Murray, Douglas, Morck, Maurice M, Moloney
Publikováno v:
Plant biotechnology journal. 8(5)
The evolution of the seed system provides enormous adaptability to the gymnosperms and angiosperms, because of the properties of dormancy, nutrient storage and seedling vigour. Many of the unique properties of seeds can be exploited in molecular farm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eade3bddd4cb7fa451c9d15c8cd820f7
https://pubmed.ncbi.nlm.nih.gov/20500681
https://pubmed.ncbi.nlm.nih.gov/20500681
Autor:
Nancy A. Markley, Maurice M. Moloney, Elizabeth Wanda Murray, H. Joseph Goren, Richard Keon, Cory Nykiforuk, Joseph Boothe
Publikováno v:
Plant biotechnology journal. 4(1)
The increased incidence of diabetes, coupled with the introduction of alternative delivery methods that rely on higher doses, is expected to result in a substantial escalation in the demand for affordable insulin in the future. Limitations in the cap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c169579e777719a62b91faef8d1af020
https://pubmed.ncbi.nlm.nih.gov/17177787
https://pubmed.ncbi.nlm.nih.gov/17177787