Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Josep-Lluís Parra"'
Autor:
Meritxell Bellet, Faten Ahmad, Rafael Villanueva, Carolina Valdivia, Julián Palomino-Doza, Ada Ruiz, Xavier Gonzàlez, Encarna Adrover, Analía Azaro, Maria Valls-Margarit, Josep Lluís Parra, Juan Aguilar, Maria Vidal, Anastasi Martín, Joaquín Gavilá, Santiago Escrivá-de-Romaní, Antonia Perelló, Cristina Hernando, Ainhara Lahuerta, Pilar Zamora, Victoria Reyes, María Alcalde, Helena Masanas, Pamela Céliz, Isabel Ruíz, Miguel Gil, Miguel Àngel Seguí, Lorena de la Peña
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 11 (2019)
Drug–drug interactions are of significant concern in clinical practice in oncology, particularly in patients receiving Cyclin-dependent kinase (CDK) 4/6 inhibitors, which are typically exposed to long-term regimens. This article presents the highli
Externí odkaz:
https://doaj.org/article/90c5d8caa4924ce685b690ebd1b8579b
Autor:
José Baselga, Joan Seoane, Maurizio Scaltriti, Paolo Nuciforo, Ludmila Prudkin, Joaquín Arribas, Javier Hernández-Losa, Judit Grueso, Leticia De Mattos-Arruda, Josep-Lluís Parra, Ginevra Caratù, Daniel Silberschmidt, Enriqueta Felip, Xose S. Puente, Ana Vivancos, Violeta Serra
Supplementary Table 1 - XLSX 39K, Exome sequencing results. The table contains the raw data for Figure 2B as well as the mutation allele frequency, the prediction of protein functionality, the inclusion in the Cancer Gene Census and the protein funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1abca89c748d1b366ff73c1756de4a72
https://doi.org/10.1158/2159-8290.22528589.v1
https://doi.org/10.1158/2159-8290.22528589.v1
Autor:
José Baselga, Joan Seoane, Maurizio Scaltriti, Paolo Nuciforo, Ludmila Prudkin, Joaquín Arribas, Javier Hernández-Losa, Judit Grueso, Leticia De Mattos-Arruda, Josep-Lluís Parra, Ginevra Caratù, Daniel Silberschmidt, Enriqueta Felip, Xose S. Puente, Ana Vivancos, Violeta Serra
Supplementary Figures - PDF file 585K, Supplementary Figure 1. Fluorescence in situ hybridization (FISH) of HER2. Supplementary Figure 2. EGFR and HER2 mutations identified. Supplementary Figure 3. Comparisons of allele frequencies. Supplementary Fig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ae505adb14b92ed9fa81e783d88ed5
https://doi.org/10.1158/2159-8290.22528592
https://doi.org/10.1158/2159-8290.22528592
HER2 is a tyrosine kinase receptor whose overexpression in breast cancers correlates with poor prognosis. A subset of HER2-positive tumors also expresses a series of HER2 fragments, collectively known as p95HER2. These fragments are emerging as a val
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145d0ccf282304a75a86836aa05ca34c
https://doi.org/10.1158/1078-0432.c.6518960.v1
https://doi.org/10.1158/1078-0432.c.6518960.v1
Related Article from HER2 Fragmentation and Breast Cancer Stratification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a3c25e554bcc4e7b4e97a575b28b43
https://doi.org/10.1158/1078-0432.22442153
https://doi.org/10.1158/1078-0432.22442153
Autor:
Joaquín Arribas, Josep Villanueva, José Baselga, Josep Tabernero, Roger R. Gomis, Francesc Canals, Jordi Giralt, Nerea Peiró Navalpotro, Antonio Luque-García, Rocio Vicario, Cristina Bernadó Morales, Marc Guiu, Josep Lluís Parra-Palau, Kim Pedersen, Mariano F. Zacarias Fluck, Pier Davide Angelini
PDF file - 62K, The tyrosine kinase inhibitor lapatinib does not revert the cellular senescence induced by p95HER2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6faeb6e498c47e95061987aa201ed603
https://doi.org/10.1158/0008-5472.22397109.v1
https://doi.org/10.1158/0008-5472.22397109.v1
Autor:
Joaquín Arribas, Josep Villanueva, José Baselga, Josep Tabernero, Roger R. Gomis, Francesc Canals, Jordi Giralt, Nerea Peiró Navalpotro, Antonio Luque-García, Rocio Vicario, Cristina Bernadó Morales, Marc Guiu, Josep Lluís Parra-Palau, Kim Pedersen, Mariano F. Zacarias Fluck, Pier Davide Angelini
PDF file - 65K, Growth of a mixture 1:1 of MCF7 Tet-off / p95HER2 and MDA-MB-231 / Luc cells in the presence or absence of doxycycline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b17878c2cd22b08319b156727d8757d
https://doi.org/10.1158/0008-5472.22397097.v1
https://doi.org/10.1158/0008-5472.22397097.v1
Autor:
Joaquín Arribas, Josep Villanueva, José Baselga, Josep Tabernero, Roger R. Gomis, Francesc Canals, Jordi Giralt, Nerea Peiró Navalpotro, Antonio Luque-García, Rocio Vicario, Cristina Bernadó Morales, Marc Guiu, Josep Lluís Parra-Palau, Kim Pedersen, Mariano F. Zacarias Fluck, Pier Davide Angelini
PDF file - 136K, Expression of p95HER2 leads to senescence in MCF7 cell xenografts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0418c7c1356d5d8423f7a15ae7afac
https://doi.org/10.1158/0008-5472.22397106
https://doi.org/10.1158/0008-5472.22397106
Autor:
Joaquín Arribas, Josep Villanueva, José Baselga, Josep Tabernero, Roger R. Gomis, Francesc Canals, Jordi Giralt, Nerea Peiró Navalpotro, Antonio Luque-García, Rocio Vicario, Cristina Bernadó Morales, Marc Guiu, Josep Lluís Parra-Palau, Kim Pedersen, Mariano F. Zacarias Fluck, Pier Davide Angelini
XLSX file - 225K, Log2FC of the 1631 gene transcripts regulated in MCF7 Tet-Off/p95HER2 60 hours after doxycycline removal and log2FC of the same transcripts in MCF7 Tet-Off/HER2 cells under the same conditions; Log2FC of the 361 genes products upreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c3be4e6e165da30dfe9d7069e6fab3
https://doi.org/10.1158/0008-5472.22397091.v1
https://doi.org/10.1158/0008-5472.22397091.v1
Autor:
Joaquín Arribas, Josep Villanueva, José Baselga, Josep Tabernero, Roger R. Gomis, Francesc Canals, Jordi Giralt, Nerea Peiró Navalpotro, Antonio Luque-García, Rocio Vicario, Cristina Bernadó Morales, Marc Guiu, Josep Lluís Parra-Palau, Kim Pedersen, Mariano F. Zacarias Fluck, Pier Davide Angelini
PDF file - 104K, Expression of p95HER2 in MCF10A, T47D and MDA-MB-453 cells and expression of HER2 in MCF7 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ce0eab92bfc4e5e53b439ba85b97a8
https://doi.org/10.1158/0008-5472.22397115
https://doi.org/10.1158/0008-5472.22397115