Zobrazeno 1 - 10
of 255
pro vyhledávání: '"Josep M Cruzado"'
Autor:
Paula Anton-Pampols, Laura Martinez Valenzuela, Loreto Fernandez Lorente, Maria Quero Ramos, Francisco Gómez Preciado, Montserrat Gomà, Joaquin Manrique, Xavier Fulladosa, Josep M Cruzado, Juan Torras, Juliana Bordignon Draibe
Publikováno v:
RMD Open, Vol 10, Iss 4 (2024)
Objective The PD-1 axis promotes protection against autoimmunity. Immune checkpoint (IC) molecules performance in anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) remains unknown. This study aims to assess the IC pathway’s role in t
Externí odkaz:
https://doaj.org/article/3ae5f5980edd4a6f96cee4610fd9245f
Autor:
Carmen Herranz, Francesca Mateo, Alexandra Baiges, Gorka Ruiz de Garibay, Alexandra Junza, Simon R Johnson, Suzanne Miller, Nadia García, Jordi Capellades, Antonio Gómez, August Vidal, Luis Palomero, Roderic Espín, Ana I Extremera, Eline Blommaert, Eva Revilla‐López, Berta Saez, Susana Gómez‐Ollés, Julio Ancochea, Claudia Valenzuela, Tamara Alonso, Piedad Ussetti, Rosalía Laporta, Antoni Xaubet, José A Rodríguez‐Portal, Ana Montes‐Worboys, Carlos Machahua, Jaume Bordas, Javier A Menendez, Josep M Cruzado, Roser Guiteras, Christophe Bontoux, Concettina La Motta, Aleix Noguera‐Castells, Mario Mancino, Enrique Lastra, Raúl Rigo‐Bonnin, Jose C Perales, Francesc Viñals, Alvaro Lahiguera, Xiaohu Zhang, Daniel Cuadras, Coline H M van Moorsel, Joanne J van der Vis, Marian J R Quanjel, Harilaos Filippakis, Razq Hakem, Chiara Gorrini, Marc Ferrer, Aslihan Ugun‐Klusek, Ellen Billett, Elżbieta Radzikowska, Álvaro Casanova, María Molina‐Molina, Antonio Roman, Oscar Yanes, Miquel A Pujana
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 9, Pp 1-21 (2021)
Abstract Inhibition of mTOR is the standard of care for lymphangioleiomyomatosis (LAM). However, this therapy has variable tolerability and some patients show progressive decline of lung function despite treatment. LAM diagnosis and monitoring can al
Externí odkaz:
https://doaj.org/article/51f572bcdff644bcab3c3cc538fd0d47
Autor:
Sílvia Collado, Elisabeth Coll, Carlos Nicolau, Manel Azqueta, Mercedes Pons, Josep M Cruzado, Bernat de la Torre, Ramón Deulofeu, Sergi Mojal, Julio Pascual, Aleix Cases
Publikováno v:
BMC Nephrology, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background To assess whether serum osteoprotegerin (OPG) and/or fetuin-A predict mortality and cardiovascular (CV) morbidity and mortality in hemodialysis patients. Methods Multicenter, observational, prospective study that included 220 hemo
Externí odkaz:
https://doaj.org/article/b19661e9eb094f4c9c10860c28a52647
Autor:
Alonso Narváez, Roser Guiteras, Anna Sola, Anna Manonelles, Juan Morote, Juan Torras, Josep M Grinyó, Josep M Cruzado
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215232 (2019)
BackgroundThe costimulatory CD40-CD40L pathway plays a role in kidney inflammation. We have previously reported that renal CD40 upregulation precedes cellular interstitial infiltrate and fibrosis in the unilateral ureteral obstruction (UUO) model. He
Externí odkaz:
https://doaj.org/article/f3b33dfb424e4386a4b43c0d4b2c3332
Autor:
Ines Rama, Ines Llaudó, Pere Fontova, Gema Cerezo, Carlos Soto, Casimiro Javierre, Miguel Hueso, Nuria Montero, Alberto Martínez-Castelao, Juan Torras, Josep M Grinyó, Josep M Cruzado, Nuria Lloberas
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164969 (2016)
Patients undergoing conventional hemodialysis (C-HD) present a greater immuno-inflammatory state probably related to uremia, sympathetic nervous system (SNS) activation and /or membrane bioincompatibility, which could improve with a technique-switchi
Externí odkaz:
https://doaj.org/article/9e69733e077c47f0b182c2c9a1d8f6e3
Autor:
Fernanda Ortiz, Rosana Gelpi, Ilkka Helanterä, Edoardo Melilli, Eero Honkanen, Oriol Bestard, Josep M Grinyo, Josep M Cruzado
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0159717 (2016)
The pros and cons for implementing protocol biopsies (PB) after kidney transplantation are still a matter of debate. We aimed to address the frequency of pathological findings in PB, to analyze their impact on long-term graft survival (GS) and to ana
Externí odkaz:
https://doaj.org/article/f5e5d1626dbc426394ab383e16b789d1
Autor:
Elena Crespo, Marc Lucia, Josep M Cruzado, Sergio Luque, Edoardo Melilli, Anna Manonelles, Nuria Lloberas, Joan Torras, Josep M Grinyó, Oriol Bestard
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117618 (2015)
Preformed T-cell immune-sensitization should most likely impact allograft outcome during the initial period after kidney transplantation, since donor-specific memory T-cells may rapidly recognize alloantigens and activate the effector immune response
Externí odkaz:
https://doaj.org/article/27d01757638645c5a419df5994dd4a55
Autor:
Sílvia Collado, Elisabeth Coll, Carlos Nicolau, Mercedes Pons, Josep M Cruzado, Julio Pascual, Aleix Cases
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127344 (2015)
To evaluate the predictive value of carotid atherosclerotic disease (CAD) and intima-media thickness (IMT) on incident cardiovascular disease and mortality in hemodialysis patients.Multicenter, observational, prospective study including 110 patients,
Externí odkaz:
https://doaj.org/article/beaa51b61ebd4c14b20ff82eabe32ca6
Autor:
Èlia Ripoll, Ana Merino, Immaculada Herrero-Fresneda, Josep M Aran, Montse Goma, Nuria Bolaños, Laura de Ramon, Oriol Bestard, Josep M Cruzado, Josep M Grinyó, Juan Torras
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65068 (2013)
Lupus nephritis (LN) is an autoimmune disorder in which co-stimulatory signals have been involved. Here we tested a cholesterol-conjugated-anti-CD40-siRNA in dendritic cells (DC) in vitro and in a model of LPS to check its potency and tissue distribu
Externí odkaz:
https://doaj.org/article/ddac516d3318448f99213346262285bd
Autor:
Gemma Chiva-Blanch, Pepita Giménez-Bonafe, Inés Llaudó, Joan Torras, Josep M Cruzado, Jordi Pétriz, Esther Castaño, Marcella Franquesa, Avelina Tortosa, Immaculada Herrero-Fresneda, Inés Rama, Oriol Bestard, Josep M Grinyó, Núria LLoberas
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 12, Iss 3 (2009)
P-glycoprotein (Pgp), a protein codified by Multi Drug Resistance (MDR1) gene, has a detoxifying function and might influence the toxicity and pharmacokinetics and pharmacodynamics of drugs. Sampling strategies to improve Pgp studies could be useful
Externí odkaz:
https://doaj.org/article/afae8c450f834c4486e8a98ebffeb3af