Zobrazeno 1 - 10
of 403
pro vyhledávání: '"Josep M Cruzado"'
Autor:
Sergi Codina, Laia Oliveras, Eva Ferreiro, Aroa Rovira, Ana Coloma, Nuria Lloberas, Edoardo Melilli, Miguel Hueso, Fabrizio Sbraga, Enric Boza, José M. Vazquez, José L. Pérez-Fernández, Joan Sabater, Josep M. Cruzado, Nuria Montero
Publikováno v:
Frontiers in Nephrology, Vol 4 (2024)
IntroductionCardiac surgery-associated acute kidney injury (CSA-AKI) is a well-known complication that increases morbidity and mortality rates. The objective of this study was to reduce CSA-AKI through nephrologist intervention in patients awaiting c
Externí odkaz:
https://doaj.org/article/0d1aa2c25b4647edb4398e004048bea2
Autor:
Paula Anton-Pampols, Laura Martinez Valenzuela, Loreto Fernandez Lorente, Maria Quero Ramos, Francisco Gómez Preciado, Montserrat Gomà, Joaquin Manrique, Xavier Fulladosa, Josep M Cruzado, Juan Torras, Juliana Bordignon Draibe
Publikováno v:
RMD Open, Vol 10, Iss 4 (2024)
Objective The PD-1 axis promotes protection against autoimmunity. Immune checkpoint (IC) molecules performance in anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) remains unknown. This study aims to assess the IC pathway’s role in t
Externí odkaz:
https://doaj.org/article/3ae5f5980edd4a6f96cee4610fd9245f
Autor:
Melissa Rau, Adrian Santelli, Sara Martí, María Isabel Díaz, Nuria Sabé, María Fiol, Luis Riera, Begoña Etcheverry, Sergi Codina, Ana Coloma, Anna Carreras-Salinas, Carmen Ardanuy, Josep M. Cruzado, Edoardo Melilli
Publikováno v:
Nefrología (English Edition), Vol 44, Iss 3, Pp 408-416 (2024)
Background: Studies analyzing non-antibiotic alternatives in kidney transplant UTI's are lacking. d-Mannose, a simple sugar, inhibits bacterial attachment to the urothelium, as does Proanthocyanidins; both could act as a synergic strategy preventing
Externí odkaz:
https://doaj.org/article/41caaeb0cd674b088b6dcfc76221bffa
Autor:
Beatriz Fernández-Alarcón, Oscar Nolberger, Anna Vidal-Alabró, Raul Rigo-Bonnin, Josep M. Grinyó, Edoardo Melilli, Nuria Montero, Anna Manonelles, Ana Coloma, Alex Favà, Sergi Codina, Josep M. Cruzado, Helena Colom, Nuria Lloberas
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
AimsThe once-daily extended-release tacrolimus formulation (ER-Tac) has demonstrated similar efficacy and safety to the twice-daily immediate-release formulation (IR-Tac), but few population-based pharmacokinetic models have been developed in de novo
Externí odkaz:
https://doaj.org/article/e1e7a764787d4907916c5088a819c282
Autor:
Anna Vidal-Alabró, Helena Colom, Pere Fontova, Gema Cerezo, Edoardo Melilli, Nuria Montero, Ana Coloma, Anna Manonelles, Alex Favà, Josep M. Cruzado, Joan Torras, Josep M. Grinyó, Nuria Lloberas
Publikováno v:
Nefrología (English Edition), Vol 44, Iss 2, Pp 204-216 (2024)
Background and justification: The strategy of the concentration-dose (C/D) approach and the different profiles of tacrolimus (Tac) according to the cytochrome P450 polymorphisms (CYPs) focus on the metabolism of Tac and are proposed as tools for the
Externí odkaz:
https://doaj.org/article/080bb41af9964a478495db2667e29f1c
Autor:
Anna Vidal-Alabró, Helena Colom, Pere Fontova, Gema Cerezo, Edoardo Melilli, Núria Montero, Ana Coloma, Anna Manonellas, Alexandre Favà, Josep M. Cruzado, Joan Torras, Josep M. Grinyó, Núria Lloberas
Publikováno v:
Nefrología, Vol 44, Iss 2, Pp 204-216 (2024)
Resumen: Antecedentes y justificación: La estrategia de la aproximación concentración-dosis (C/D) y los distintos perfiles del tacrolimus (Tac), según los polimorfismos del citocromo P450 (CYPs) se centran en el metabolismo de Tac y se plantean c
Externí odkaz:
https://doaj.org/article/05d6c0eae98441bc9adb797370fdde68
Autor:
Zeyar Mohammed Ali, Marinda Meertens, Beatriz Fernández, Pere Fontova, Anna Vidal-Alabró, Raul Rigo-Bonnin, Edoardo Melilli, Josep M. Cruzado, Josep M. Grinyó, Helena Colom, Nuria Lloberas
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2699 (2023)
The aim of the study is to develop a population pharmacokinetic (PopPK) model and to investigate the influence of CYP3A5/CYP3A4 and ABCB1 single nucleotide polymorphisms (SNPs) on the Tacrolimus PK parameters after LCP-Tac formulation in stable adult
Externí odkaz:
https://doaj.org/article/9d949f15b70a4ab1b8f23ab50ab7990f
Autor:
Carmen Herranz, Francesca Mateo, Alexandra Baiges, Gorka Ruiz de Garibay, Alexandra Junza, Simon R Johnson, Suzanne Miller, Nadia García, Jordi Capellades, Antonio Gómez, August Vidal, Luis Palomero, Roderic Espín, Ana I Extremera, Eline Blommaert, Eva Revilla‐López, Berta Saez, Susana Gómez‐Ollés, Julio Ancochea, Claudia Valenzuela, Tamara Alonso, Piedad Ussetti, Rosalía Laporta, Antoni Xaubet, José A Rodríguez‐Portal, Ana Montes‐Worboys, Carlos Machahua, Jaume Bordas, Javier A Menendez, Josep M Cruzado, Roser Guiteras, Christophe Bontoux, Concettina La Motta, Aleix Noguera‐Castells, Mario Mancino, Enrique Lastra, Raúl Rigo‐Bonnin, Jose C Perales, Francesc Viñals, Alvaro Lahiguera, Xiaohu Zhang, Daniel Cuadras, Coline H M van Moorsel, Joanne J van der Vis, Marian J R Quanjel, Harilaos Filippakis, Razq Hakem, Chiara Gorrini, Marc Ferrer, Aslihan Ugun‐Klusek, Ellen Billett, Elżbieta Radzikowska, Álvaro Casanova, María Molina‐Molina, Antonio Roman, Oscar Yanes, Miquel A Pujana
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 9, Pp 1-21 (2021)
Abstract Inhibition of mTOR is the standard of care for lymphangioleiomyomatosis (LAM). However, this therapy has variable tolerability and some patients show progressive decline of lung function despite treatment. LAM diagnosis and monitoring can al
Externí odkaz:
https://doaj.org/article/51f572bcdff644bcab3c3cc538fd0d47
Autor:
Pere Fontova, Lisanne N. van Merendonk, Anna Vidal-Alabró, Raül Rigo-Bonnin, Gema Cerezo, Stefaan van Oevelen, Oriol Bestard, Edoardo Melilli, Nuria Montero, Ana Coloma, Anna Manonelles, Joan Torras, Josep M. Cruzado, Josep M. Grinyó, Helena Colom, Nuria Lloberas
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1481 (2023)
Despite intensive monitoring of whole blood tacrolimus concentrations, acute rejection after kidney transplantation occurs during tacrolimus therapy. Intracellular tacrolimus concentrations could better reflect exposure at the site of action and its
Externí odkaz:
https://doaj.org/article/17151f14f7b844a0abfe1718be0a1db2
Autor:
Elena Crespo, Anna Vidal-Alabró, Thomas Jouve, Pere Fontova, Maik Stein, Sonila Mocka, Maria Meneghini, Anett Sefrin, Petra Hruba, Montserrat Gomà, Alba Torija, Laura Donadeu, Alex Favà, Josep M. Cruzado, Edoardo Melilli, Francesc Moreso, Ondrej Viklicky, Frederike Bemelman, Petra Reinke, Josep Grinyó, Nuria Lloberas, Oriol Bestard
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Achieving fast immunosuppression blood exposure after kidney transplantation is key to abrogating both preformed and de novo anti-donor humoral and cellular alloresponses. However, while tacrolimus (TAC) is the cornerstone immunosuppressant inhibitin
Externí odkaz:
https://doaj.org/article/e1f40afe8ab94a93a922e44c70f720c5