Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Josep Lluís Gelpí"'
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 6, p e1012173 (2024)
Interactive Jupyter Notebooks in combination with Conda environments can be used to generate FAIR (Findable, Accessible, Interoperable and Reusable/Reproducible) biomolecular simulation workflows. The interactive programming code accompanied by docum
Externí odkaz:
https://doaj.org/article/3d06dcac195746eab6375d2b780d6aec
Autor:
Ignasi Esteban, Carmen Pastor-Quiñones, Lorena Usero, Elena Aurrecoechea, Lorenzo Franceschini, Arthur Esprit, Josep Lluís Gelpí, Francisco Martínez-Jiménez, Núria López-Bigas, Karine Breckpot, Kris Thielemans, Lorna Leal, Carmen Elena Gómez, Marta Sisteré-Oró, Andreas Meyerhans, Mariano Esteban, María José Alonso, Felipe García, Montserrat Plana
Publikováno v:
Vaccines, Vol 12, Iss 1, p 15 (2023)
The COVID-19 pandemic has brought significant changes and advances in the field of vaccination, including the implementation and widespread use of encapsidated mRNA vaccines in general healthcare practice. Here, we present two new mRNAs expressing an
Externí odkaz:
https://doaj.org/article/5049aac8017e41528739adfc92cee953
Autor:
Adrià Aterido, Antonio Julià, Patricia Carreira, Ricardo Blanco, José Javier López-Longo, José Javier Pérez Venegas, Àlex Olivé, José Luís Andreu, Maria Ángeles Aguirre-Zamorano, Paloma Vela, Joan M. Nolla, José Luís Marenco-de la Fuente, Antonio Zea, José María Pego, Mercedes Freire, Elvira Díez, María López-Lasanta, Mireia López-Corbeto, Núria Palau, Raül Tortosa, Josep Lluís Gelpí, Devin Absher, Richard M Myers, Antonio Fernández-Nebro, Sara Marsal
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-11 (2017)
Abstract Background Systemic lupus erythematosus (SLE) is a genetically complex rheumatic disease characterized by heterogeneous clinical manifestations of unknown etiology. Recent studies have suggested the existence of a genetic basis for SLE heter
Externí odkaz:
https://doaj.org/article/462ceb3ec4e54a95a3eaec684b37d99b
Autor:
Michela Candotti, Alberto Pérez, Carles Ferrer-Costa, Manuel Rueda, Tim Meyer, Josep Lluís Gelpí, Modesto Orozco
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 12, p e1003393 (2013)
After decades of using urea as denaturant, the kinetic role of this molecule in the unfolding process is still undefined: does urea actively induce protein unfolding or passively stabilize the unfolded state? By analyzing a set of 30 proteins (repres
Externí odkaz:
https://doaj.org/article/ab704e69288b457eb30afe1d6e652e32
Autor:
Sarah Djebali, Julien Lagarde, Philipp Kapranov, Vincent Lacroix, Christelle Borel, Jonathan M Mudge, Cédric Howald, Sylvain Foissac, Catherine Ucla, Jacqueline Chrast, Paolo Ribeca, David Martin, Ryan R Murray, Xinping Yang, Lila Ghamsari, Chenwei Lin, Ian Bell, Erica Dumais, Jorg Drenkow, Michael L Tress, Josep Lluís Gelpí, Modesto Orozco, Alfonso Valencia, Nynke L van Berkum, Bryan R Lajoie, Marc Vidal, John Stamatoyannopoulos, Philippe Batut, Alex Dobin, Jennifer Harrow, Tim Hubbard, Job Dekker, Adam Frankish, Kourosh Salehi-Ashtiani, Alexandre Reymond, Stylianos E Antonarakis, Roderic Guigó, Thomas R Gingeras
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e28213 (2012)
The classic organization of a gene structure has followed the Jacob and Monod bacterial gene model proposed more than 50 years ago. Since then, empirical determinations of the complexity of the transcriptomes found in yeast to human has blurred the d
Externí odkaz:
https://doaj.org/article/812c3a8d26464239be0aee257e827b33
Publikováno v:
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Dipòsit Digital de la UB
Universidad de Barcelona
Universitat Politècnica de Catalunya (UPC)
Dipòsit Digital de la UB
Universidad de Barcelona
We present BioExcel Building Blocks Workflows, a web-based graphical user interface (GUI) offering access to a collection of transversal pre-configured biomolecular simulation workflows assembled with the BioExcel Building Blocks library. Available w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7dda3121e5b31c282eaebafeb0328c9
https://hdl.handle.net/2117/370057
https://hdl.handle.net/2117/370057
Autor:
Adam Hospital, Genís Bayarri, Stian Soiland- Reyes, Douglas Lowe, Josep Lluís Gelpí, Pau Andrio, Daniele Lezzi, Jorge Ejarque, Sarah Butcher, Ania Niewielska, Alberto Eusebi, Esther Sala, Aristarc Surinach, Martí Municoy, Rosa Maria Badia, Rodrigo Vargas, Alexandre Bonvin
This deliverable presents the final release of demonstration workflows for the BioExcel-2 project, including a wrap-up of all the work done for the BioBB library, its associated workflows, and a final analysis of the milestones achieved from the init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d5f4016c8cff24b7fe30a2d40d696d
Autor:
Aristarc Suriñach, Adam Hospital, Yvonne Westermaier, Luis Jordà, Sergi Orozco-Ruiz, Daniel Beltrán, Francesco Colizzi, Pau Andrio, Robert Soliva, Martí Municoy, Josep Lluís Gelpí, Modesto Orozco
Mutations in the kinase domain of the Epidermal Growth Factor Receptor (EGFR) can be drivers of cancer and also trigger drug resistance in patients under chemotherapy treatment based on kinase inhibitors use. A priori knowledge of the impact of EGFR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::175f285173519ec1f63ef57c4582451e
https://doi.org/10.1101/2022.04.25.489389
https://doi.org/10.1101/2022.04.25.489389
Publikováno v:
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Dipòsit Digital de la UB
Universidad de Barcelona
Universitat Politècnica de Catalunya (UPC)
Dipòsit Digital de la UB
Universidad de Barcelona
Motivation The BioExcel Building Blocks (BioBB) library offers a broad collection of wrappers on top of common biomolecular simulation and bioinformatics tools. The possibility to access the library remotely and programmatically increases its usabili
Autor:
Aristarc Suriñach, Adam Hospital, Yvonne Westermaier, Luis Jordà, Sergi Orozco-Ruiz, Daniel Beltrán, Francesco Colizzi, Pau Andrio, Robert Soliva, Martí Municoy, Josep Lluís Gelpí, Modesto Orozco
14 pages, 6 figures, 1 table, supporting information https://pubs.acs.org/doi/10.1021/acs.jcim.2c01344.-- The code for this work is available at https://github.com/bioexcel/biobb_hpc_workflows/tree/condapack. MD simulations are available from our MDp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac9fde04c21be9e4c703907677b4022
https://hdl.handle.net/2117/383723
https://hdl.handle.net/2117/383723