Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Josep Llaveria"'
Autor:
Elsie Diaz, Suraj Adhikary, Armand W. J. W. Tepper, Daniel Riley, Rodrigo Ortiz-Meoz, Daniel Krosky, Christophe Buyck, Carolina Martinez Lamenca, Josep Llaveria, Lichao Fang, Jay H. Kalin, Vincent N. A. Klaren, Shorouk Fahmy, Paul L. Shaffer, Robert Kirkpatrick, Rodrigo J. Carbajo, Maren Thomsen, Antonietta Impagliazzo
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Rational engineering of human spermine oxidase yields crystallizable structures and the design of an allosteric inhibitor.
Externí odkaz:
https://doaj.org/article/391009d10cb04621862722699df90a61
Autor:
Brenda Pijper, Raúl Martín, Alberto J. Huertas-Alonso, Maria Lourdes Linares, Enol López, Josep Llaveria, Ángel Díaz-Ortiz, Darren J. Dixon, Antonio de la Hoz, Jesús Alcázar
Publikováno v:
Organic Letters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2130e47c0984f584bb262a821f1a4f54
https://doi.org/10.1021/acs.orglett.3c01390
https://doi.org/10.1021/acs.orglett.3c01390
Autor:
Suzanne Ackloo, Albert A. Antolin, Jose Manuel Bartolome, Hartmut Beck, Alex Bullock, Ulrich A. K. Betz, Jark Böttcher, Peter J. Brown, Menorca Chaturvedi, Alisa Crisp, Danette Daniels, Jan Dreher, Kristina Edfeldt, Aled M. Edwards, Ursula Egner, Jon Elkins, Christian Fischer, Tine Glendorf, Steven Goldberg, Ingo V. Hartung, Alexander Hillisch, Evert Homan, Stefan Knapp, Markus Köster, Oliver Krämer, Josep Llaveria, Uta Lessel, Sven Lindemann, Lars Linderoth, Hisanori Matsui, Maurice Michel, Florian Montel, Anke Mueller-Fahrnow, Susanne Müller, Dafydd R. Owen, Kumar Singh Saikatendu, Vijayaratnam Santhakumar, Wendy Sanderson, Cora Scholten, Matthieu Schapira, Sujata Sharma, Brock Shireman, Michael Sundström, Matthew H. Todd, Claudia Tredup, Jennifer Venable, Timothy M. Willson, Cheryl H. Arrowsmith
Publikováno v:
RSC Medicinal Chemistry.
Target 2035, an international federation of biomedical scientists from the public and private sectors, is leveraging ‘open’ principles to develop a pharmacological tool for every human protein.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3307d439e596fca276308b7255fe64f6
https://doi.org/10.1039/d2md00441k
https://doi.org/10.1039/d2md00441k
Autor:
Timothée Constantin, Bartosz Górski, Michael J. Tilby, Saloua Chelli, Fabio Juliá, Josep Llaveria, Kevin J. Gillen, Hendrik Zipse, Sami Lakhdar, Daniele Leonori
Publikováno v:
Constantin, T, Górski, B, Tilby, M J, Chelli, S, Julia Hernandez, F, Llaveria, J, Gillen, K J, Zipse, H, Lakhdar, S & Leonori, D 2022, ' Halogen-atom and group transfer reactivity enabled by hydrogen tunneling ', Science, vol. 377, no. 6612, pp. 1323-1328 . https://doi.org/10.1126/science.abq8663
The generation of carbon radicals by halogen-atom and group transfer reactions is generally achieved using tin and silicon reagents that maximize the interplay of enthalpic (thermodynamic) and polar (kinetic) effects. In this work, we demonstrate a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3301b3ec6f06db1972c7df507ce3713
https://pubmed.ncbi.nlm.nih.gov/36108027
https://pubmed.ncbi.nlm.nih.gov/36108027
Publikováno v:
Organic Letters
Resolvins D3 and E1 are important signaling molecules in the resolution of inflammation. Here, we report a convergent and flexible strategy to prepare these natural products using Hiyama–Denmark coupling of five- and six-membered cyclic alkenylsilo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb963ff7827630407ee278c6b47694ca
https://doi.org/10.1021/acs.orglett.0c00089
https://doi.org/10.1021/acs.orglett.0c00089
Autor:
Daniele Leonori, Ji Hye Kim, Nadeem S. Sheikh, Timothée Constantin, Josep Llaveria, Marco Simonetti
Publikováno v:
Kim, J H, Constantin, T, Simonetti, M, Llaveria, J, Sheikh, N S & Leonori, D 2021, ' A radical approach for the selective C–H borylation of azines ', Nature . https://doi.org/10.1038/s41586-021-03637-6
Boron functional groups are often introduced in place of aromatic carbon–hydrogen bonds to expedite small-molecule diversification through coupling of molecular fragments1–3. Current approaches based on transition-metal-catalysed activation of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d2c5221b68e13ff4a70dbb227530c9
https://pubmed.ncbi.nlm.nih.gov/34015802
https://pubmed.ncbi.nlm.nih.gov/34015802
Autor:
Rudy Lhermet, Robert Stade, Alois Fürstner, Peter Persich, Azusa Kondoh, Josep Llaveria, Teresa de Haro
Publikováno v:
Chemistry-A European Journal
A new generation of alkyne metathesis catalysts, which are distinguished by high activity and an exquisite functional group tolerance, allows the scope of this transformation to be extended beyond its traditional range. They accept substrates that we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b604c307a05527cb7795e80fba5f08
https://doi.org/10.1002/chem.201302320
https://doi.org/10.1002/chem.201302320
Publikováno v:
Chemistry - A European Journal. 19:4532-4537
A concise and largely catalysis-based approach to the potent algal toxin polycavernoside A (1) is described that intercepts a late-stage intermediate of a previous total synthesis; from there on, this challenging target can be reached in a small numb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c64cb99e08c0327a42dc3f6ee6f847
https://doi.org/10.1002/chem.201204551
https://doi.org/10.1002/chem.201204551
Autor:
Yolanda Díaz, Mariam Azzouz, M. Isabel Matheu, Sergio Castillón, Patricia Marcé, Sebastien Soriano, Josep Llaveria
Publikováno v:
ChemInform. 47
A formal enantioselective synthesis of nectrisine, a potent α-glucosidase inhibitor, was carried out starting from butadiene monoepoxide through a synthetic sequence involving enantioselective allylic substitution, cross-metathesis, dihydroxylation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efb9c67391cf29fa60f7ea79966dd440
https://doi.org/10.1002/chin.201645183
https://doi.org/10.1002/chin.201645183
Autor:
Sebastien Soriano, Mariam Azzouz, Patricia Marcé, M. Isabel Matheu, Sergio Castillón, Yolanda Díaz, Josep Llaveria
Publikováno v:
Journal of Organic Chemistry
Filiació URV: SI A formal enantioselective synthesis of nectrisine, a potent ¿-glucosidase inhibitor, was carried out starting from butadiene monoepoxide through a synthetic sequence involving enantioselective allylic substitution, cross-metathesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e96029a383dac08aa6429c8fae5ff99
https://pubmed.ncbi.nlm.nih.gov/27182738
https://pubmed.ncbi.nlm.nih.gov/27182738