Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Josep Bassaganya Riera"'
Autor:
Nuria Tubau-Juni, Josep Bassaganya-Riera, Andrew J. Leber, Sameeksha S. Alva, Ryan Baker, Raquel Hontecillas
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Clostridioides difficile infection (CDI) is the leading cause of antibiotic-associated diarrhea, and its clinical symptoms can span from asymptomatic colonization to pseudomembranous colitis and even death. The current standard of care for C
Externí odkaz:
https://doaj.org/article/c6144bacee3149aaa47fc7de462e72ae
Autor:
Ryan Baker, Raquel Hontecillas, Nuria Tubau-Juni, Andrew J. Leber, Shiv Kale, Josep Bassaganya-Riera
Publikováno v:
npj Systems Biology and Applications, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract We built a computational model of complex mechanisms at the intersection of immunity and metabolism that regulate CD4+ T cell effector and regulatory functions by using coupled ordinary differential equations. The model provides an improved
Externí odkaz:
https://doaj.org/article/9754d031717c4f2591084d2eeacaf939
Autor:
Nuria Tubau-Juni, Raquel Hontecillas, Andrew Leber, Panita Maturavongsadit, Jyoti Chauhan, Josep Bassaganya-Riera
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Psoriasis (PsO) is a complex immune-mediated disease that afflicts 100 million people. Omilancor is a locally-acting, small molecule that selectively activates the Lanthionine Synthetase C-like 2 (LANCL2) pathway, resulting in immunoregulato
Externí odkaz:
https://doaj.org/article/c1c4b1022cbb4c39b88270c685e5b4e6
Autor:
Bridget Kastelberg, Tariq Ayubi, Nuria Tubau-Juni, Andrew Leber, Raquel Hontecillas, Josep Bassaganya-Riera, Shiv D. Kale
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The Nlr family member X1 (Nlrx1) is an immuno-metabolic hub involved in mediating effective responses to virus, bacteria, fungi, cancer, and auto-immune diseases. We have previously shown that Nlrx1 is a critical regulator of immune signaling and mor
Externí odkaz:
https://doaj.org/article/e39ee8d27ab84fe38efeac95a51892aa
Autor:
Jiang Li, Yanfei Zhang, Alexandria L. Jilg, Donna M. Wolk, Harshit S. Khara, Amy Kolinovsky, David D. K. Rolston, Raquel Hontecillas, Josep Bassaganya-Riera, Marc S. Williams, Vida Abedi, Ming Ta Michael Lee
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundClostridioides difficile is a major cause of healthcare-associated and community-acquired diarrhea. Host genetic susceptibility to Clostridioides difficile infection has not been studied on a large-scale.MethodsA total of 1,160 Clostridioid
Externí odkaz:
https://doaj.org/article/7759557e633a45d4a3858d28110d609c
Autor:
Josep Bassaganya-Riera, Elliot M. Berry, Ellen E. Blaak, Barbara Burlingame, Johannes le Coutre, Willem van Eden, Ahmed El-Sohemy, J. Bruce German, Dietrich Knorr, Christophe Lacroix, Maurizio Muscaritoli, David C. Nieman, Michael Rychlik, Andrew Scholey, Mauro Serafini
Publikováno v:
Frontiers in Nutrition, Vol 7 (2021)
Five years ago, with the editorial board of Frontiers in Nutrition, we took a leap of faith to outline the Goals for Nutrition Science – the way we see it (1). Now, in 2020, we can put ourselves to the test and take a look back. Without a doubt we
Externí odkaz:
https://doaj.org/article/813c3f80743a43aa823a59c4a8824bad
Autor:
Bridget Kastelberg, Nuria Tubau-Juni, Tariq Ayubi, Austin Leung, Andrew Leber, Raquel Hontecillas, Josep Bassaganya-Riera, Shiv D Kale
Publikováno v:
PLoS Pathogens, Vol 16, Iss 9, p e1008854 (2020)
Aspergillus fumigatus is an opportunistic fungal pathogen of immunocompromised patient populations. Mortality is thought to be context-specific and occurs via both enhanced fungal growth and immunopathogenesis. NLRX1 is a negative regulator of immune
Externí odkaz:
https://doaj.org/article/77f386d51f08479989c5680a9aa91e55
Autor:
Vaibhav Sharma, Vishakha Sharma, Ayesha Khan, David J. Wassmer, Matthew D. Schoenholtz, Raquel Hontecillas, Josep Bassaganya-Riera, Ramin Zand, Vida Abedi
Publikováno v:
Frontiers in Nutrition, Vol 7 (2020)
Nutrition plays a vital role in health and the recovery process. Deficiencies in macronutrients and micronutrients can impact the development and progression of various disorders. However, malnutrition screening tools and their utility in the clinica
Externí odkaz:
https://doaj.org/article/0993c01996234bc6a63282faa308bbe2
Publikováno v:
Biology Direct, Vol 13, Iss 1, Pp 1-21 (2018)
Abstract Background Reproducing cell processes using an in silico system is an essential tool for understanding the underlying mechanisms and emergent properties of this extraordinary complex biological machine. However, computational models are seld
Externí odkaz:
https://doaj.org/article/eded588264b24c95b0d104403c00efa3
Autor:
Danielle L. Porier, Sarah N. Wilson, Dawn I. Auguste, Andrew Leber, Sheryl Coutermarsh-Ott, Irving C. Allen, Clayton C. Caswell, James A. Budnick, Josep Bassaganya-Riera, Raquel Hontecillas, James Weger-Lucarelli, Scott C. Weaver, Albert J. Auguste
Publikováno v:
Vaccines, Vol 9, Iss 10, p 1142 (2021)
Vaccination remains critical for viral disease outbreak prevention and control, but conventional vaccine development typically involves trade-offs between safety and immunogenicity. We used a recently discovered insect-specific flavivirus as a vector
Externí odkaz:
https://doaj.org/article/38a97a5ba5ee4c09ac815d6d7477d27c