Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Joselyn Cruz-Cruz"'
Autor:
Michael R Verneris, Elena Woods, Masanori Hayashi, Eric Hoffmeyer, Dejene Tufa, Dallas Jones, Joselyn Cruz-Cruz, Jessica A Lake, Kristin L Schaller, Joseph Fernandez, Benjamin Kooiman, Spencer C Hall
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background Advances in pediatric oncology have occurred for some cancers; however, new therapies for sarcoma have been inadequate. Cellular immunotherapy using chimeric antigen receptor (CAR) T cells has shown dramatic benefits in leukemia, lymphoma,
Externí odkaz:
https://doaj.org/article/24145721225047d3a85812ec83a824a3
Autor:
Joselyn Cruz Cruz, Kristen C. Allison, Lauren S. Page, Alexis J. Jenkins, Xiaodong Wang, H. Shelton Earp, Stephen V. Frye, Douglas K. Graham, Michael R. Verneris, Alisa B. Lee-Sherick
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundPrevious studies show that the spleen and bone marrow can serve as leukemia microenvironments in which macrophages play a significant role in immune evasion and chemoresistance. We hypothesized that the macrophage driven tolerogenic process
Externí odkaz:
https://doaj.org/article/6c936b3c3cbd434da91afc7829838a3a
Autor:
Arndt Borkhardt, Nan Qin, Stephen T Keir, Darell D Bigner, Allison Cole, Matthias Wölfl, Viktoria Marquardt, Johanna Theruvath, David Pauck, Daniel Picard, Lena Blümel, Mara Maue, Jasmin Bartl, Ulvi Ahmadov, Maike Langini, Frauke-Dorothee Meyer, Joselyn Cruz-Cruz, Claus M Graef, Till Milde, Olaf Witt, Anat Erdreich-Epstein, Gabriel Leprivier, Ulf Kahlert, Anja Stefanski, Kai Stühler, Julia Hauer, Thomas Beez, Christiane B Knobbe-Thomsen, Ute Fischer, Jörg Felsberg, Finn K Hansen, Rajeev Vibhakar, Sujatha Venkatraman, Samuel H Cheshier, Guido Reifenberger, Thomas Kurz, Marc Remke, Siddhartha Mitra
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)
Background While major advances have been made in improving the quality of life and survival of children with most forms of medulloblastoma (MB), those with MYC-driven tumors (Grp3-MB) still suffer significant morbidity and mortality. There is an urg
Externí odkaz:
https://doaj.org/article/bea518d410cc4fd58c33516272b055a1
Autor:
Senthilnath Lakshmanachetty, Joselyn Cruz-Cruz, Eric Hoffmeyer, Allison P. Cole, Siddhartha S. Mitra
Publikováno v:
Cells, Vol 10, Iss 4, p 893 (2021)
Cancer cells “hijack” host immune cells to promote growth, survival, and metastasis. The immune microenvironment of high-grade gliomas (HGG) is a complex and heterogeneous system, consisting of diverse cell types such as microglia, bone marrow-de
Externí odkaz:
https://doaj.org/article/7681ebec598b412b94cce047fc4706a4
Publikováno v:
The FEBS Journal. 288:6127-6141
Pediatric high-grade gliomas (pHGG) comprise a deadly, heterogenous category of pediatric gliomas with a clear need for more effective treatment options. Advances in high-throughput molecular techniques have enhanced molecular understanding of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c391c9d32c60f23c0b3dfa3cffd9070
https://doi.org/10.1111/febs.15739
https://doi.org/10.1111/febs.15739
Autor:
Viktoria Marquardt, Johanna Theruvath, David Pauck, Daniel Picard, Nan Qin, Lena Blümel, Mara Maue, Jasmin Bartl, Ulvi Ahmadov, Maike Langini, Frauke-Dorothee Meyer, Allison Cole, Joselyn Cruz-Cruz, Claus M Graef, Matthias Wölfl, Till Milde, Olaf Witt, Anat Erdreich-Epstein, Gabriel Leprivier, Ulf Kahlert, Anja Stefanski, Kai Stühler, Stephen T Keir, Darell D Bigner, Julia Hauer, Thomas Beez, Christiane B Knobbe-Thomsen, Ute Fischer, Jörg Felsberg, Finn K Hansen, Rajeev Vibhakar, Sujatha Venkatraman, Samuel H Cheshier, Guido Reifenberger, Arndt Borkhardt, Thomas Kurz, Marc Remke, Siddhartha Mitra
Publikováno v:
Journal for ImmunoTherapy of Cancer. 11:e005871
BackgroundWhile major advances have been made in improving the quality of life and survival of children with most forms of medulloblastoma (MB), those with MYC-driven tumors (Grp3-MB) still suffer significant morbidity and mortality. There is an urge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5471b55cfef831599420b52600f226d0
https://doi.org/10.1136/jitc-2022-005871
https://doi.org/10.1136/jitc-2022-005871
Autor:
Siddhartha Mitra, Daniel Picard, Nan Qin, Allison Cole, Joselyn Cruz Cruz, Viktoria Marquardt, Sujatha Venkataraman, Rajeev Vibhakar, Marc Remke
Publikováno v:
Neuro-Oncology. 24:vii139-vii139
BACKGROUND The expression of MYC in tumor cells regulates the tumor microenvironment through innate and adaptive immune effector cells and immune regulatory cytokines. MYC has also been shown to regulate the expression of the immune checkpoint gene p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54dbe1e0193bc32f27e8e2818ddf4005
https://doi.org/10.1093/neuonc/noac209.535
https://doi.org/10.1093/neuonc/noac209.535
Autor:
Senthil Lakshmana Chetty, Yifan Liu, Allison Cole, Joselyn Cruz Cruz, Eric Hoffmeyer, Rajeev Vibhakar, Sujatha Venkataraman, Siddhartha Mitra
Publikováno v:
Neuro-Oncology. 24:vii213-vii213
Immune response in the tumor microenvironment is modulated by the conversion of eATP to AMP to adenosine via the ecto-enzymes CD39 and CD73. Overexpression of CD73 in tumors leads to an increase in extracellular adenosine concentration and decrease i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f15fbedaf4b92c30ad18a73fb17ae089
https://doi.org/10.1093/neuonc/noac209.817
https://doi.org/10.1093/neuonc/noac209.817
Autor:
Yifan Liu, Senthil Lakshmana Chetty, Allison Cole, Joselyn Cruz Cruz, Eric Hoffmeyer, Rajeev Vibhakar, Sujatha Venkataraman, Siddhartha Mitra
Publikováno v:
Neuro-Oncology. 24:i86-i86
Immune response in the tumor microenvironment is modulated by the conversion of eATP to AMP to adenosine via the ecto-enzymes CD39 and CD73. Overexpression of CD73 in tumors leads to an increase in extracellular adenosine concentration and decrease i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b291a27f22d03dd090597834befee379
https://doi.org/10.1093/neuonc/noac079.314
https://doi.org/10.1093/neuonc/noac079.314
