Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Josefine Slater"'
Autor:
Josefine Slater, Maiken Stilling, Pelle Hanberg, Sofus Vittrup, Martin Bruun Knudsen, Sara Kousgaard Tøstesen, Josephine Olsen Kipp, Mats Bue
Publikováno v:
Antibiotics, Vol 12, Iss 5, p 907 (2023)
Co-administration of meropenem and vancomycin has been suggested as a systemic empirical antibiotic treatment of pyogenic spondylodiscitis. The aim of this study was, in an experimental porcine model, to evaluate the percentage of an 8-h dosing inter
Externí odkaz:
https://doaj.org/article/ce42992de34f41a2a7bdad8df9ba656d
Autor:
Mathias A. F. Bendtsen, Mats Bue, Pelle Hanberg, Josefine Slater, Maja B. Thomassen, Jakob Hansen, Kjeld Søballe, Kristina Öbrink-Hansen, Maiken Stilling
Publikováno v:
Bone & Joint Research, Vol 10, Iss 1, Pp 60-67 (2021)
Aims: Flucloxacillin is commonly administered intravenously for perioperative antimicrobial prophylaxis, while oral administration is typical for prophylaxis following smaller traumatic wounds. We assessed the time, for which the free flucloxacillin
Externí odkaz:
https://doaj.org/article/ba1a48368f7f4082bfbed02ef66e1d42
Autor:
Kristina Öbrink-Hansen, Anh Duc Pham, Mats Bue, Pelle Hanberg, Mathias Bendtsen, Josefine Slater, Lena E. Friberg, Anders Thorsted, Maiken Stilling
Publikováno v:
Öbrink-Hansen, K, Pham, A D, Bue, M, Hanberg, P, Bendtsen, M, Slater, J, Friberg, L E, Thorsted, A & Stilling, M 2022, ' Population Pharmacokinetics of Flucloxacillin In Bone and Soft Tissue– Standard Dosing is Not Sufficient to Achieve Therapeutic Concentrations ', Pharmaceutical Research, vol. 39, no. 7, pp. 1633-1643 . https://doi.org/10.1007/s11095-022-03197-y
Purpose: Flucloxacillin is a β-lactam penicillin commonly used in the treatment of bone and soft tissue infections. In a recent porcine study, we found surprisingly low time for which the free concentration was maintained above the minimal inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61369ab45e4e1203f5df58e07a41f48
https://pure.au.dk/portal/da/publications/population-pharmacokinetics-of-flucloxacillin-in-bone-and-soft-tissue-standard-dosing-is-not-sufficient-to-achieve-therapeutic-concentrations(67bd267a-3214-48a6-87e5-66fce99e549f).html
https://pure.au.dk/portal/da/publications/population-pharmacokinetics-of-flucloxacillin-in-bone-and-soft-tissue-standard-dosing-is-not-sufficient-to-achieve-therapeutic-concentrations(67bd267a-3214-48a6-87e5-66fce99e549f).html
Autor:
Maja B. Thomassen, Mats Bue, Maiken Stilling, Mathias Alrø Fichtner Bendtsen, Josefine Slater, Jakob Hansen, Kristina Öbrink-Hansen, Kjeld Søballe, Pelle Hanberg
Publikováno v:
Bone & Joint Research, Vol 10, Iss 1, Pp 60-67 (2021)
Bone & Joint Research
Bendtsen, M A F, Bue, M, Hanberg, P E, Slater, J, Thomassen, M, Hansen, J, Søballe, K, Öbrink-Hansen, K M & Stilling, M 2021, ' Flucloxacillin bone and soft tissue concentrations assessed by microdialysis in pigs after intravenous and oral administration ', Bone and Joint Research, vol. 10, no. 1, pp. 60-67 . https://doi.org/10.1302/2046-3758.101.BJR-2020-0250.R1
Bone & Joint Research
Bendtsen, M A F, Bue, M, Hanberg, P E, Slater, J, Thomassen, M, Hansen, J, Søballe, K, Öbrink-Hansen, K M & Stilling, M 2021, ' Flucloxacillin bone and soft tissue concentrations assessed by microdialysis in pigs after intravenous and oral administration ', Bone and Joint Research, vol. 10, no. 1, pp. 60-67 . https://doi.org/10.1302/2046-3758.101.BJR-2020-0250.R1
Aims Flucloxacillin is commonly administered intravenously for perioperative antimicrobial prophylaxis, while oral administration is typical for prophylaxis following smaller traumatic wounds. We assessed the time, for which the free flucloxacillin c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa60d726d845a5a363f81a1aea4eced
https://doi.org/10.1302/2046-3758.101.bjr-2020-0250.r1
https://doi.org/10.1302/2046-3758.101.bjr-2020-0250.r1
Autor:
Mathias A. F. Bendtsen, Pelle Hanberg, Josefine Slater, Jakob Hansen, Kristina Öbrink-Hansen, Maiken Stilling, Mats Bue
Publikováno v:
Bendtsen, M A F, Hanberg, P, Slater, J, Hansen, J, Öbrink-Hansen, K, Stilling, M & Bue, M 2022, ' Steady-state concentrations of flucloxacillin in porcine vertebral cancellous bone and intervertebral disc following oral and intravenous administration assessed by microdialysis ', European Spine Journal, vol. 31, no. 6, pp. 1508-1514 . https://doi.org/10.1007/s00586-022-07208-9
Aims: Flucloxacillin is a frequently used antibiotic in the treatment of spondylodiscitis. We assessed steady-state concentrations and time above minimal inhibitory concentration (fT > MIC) of flucloxacillin in the intervertebral disc, vertebral canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298e2670674957ae13bdcaab2fce4f8d
https://pubmed.ncbi.nlm.nih.gov/35488132
https://pubmed.ncbi.nlm.nih.gov/35488132
Autor:
Maiken Stilling, Kjeld Søballe, Mathias Alrø Fichtner Bendtsen, Nis Pedersen Jørgensen, Mats Bue, Andrea René Jørgensen, Pelle Hanberg, Josefine Slater
Publikováno v:
Slater, J, Stilling, M, Hanberg, P, Fichtner Bendtsen, M A, Jørgensen, A R, Søballe, K, Jørgensen, N P & Bue, M 2022, ' Moxifloxacin Concentrations in the Knee Joint, Tibial Bone, and Soft Tissue When Combined with Rifampicin : A Randomized Porcine Microdialysis Study ', The Journal of bone and joint surgery. American volume, vol. 104, no. 1, pp. 49-54 . https://doi.org/10.2106/JBJS.21.00549
BACKGROUND: Peri and postoperative antibiotics are key adjuvant treatment tools in the management of periprosthetic joint infection (PJI). The aim of this study was to evaluate the effect of rifampicin on the area under the moxifloxacin concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3bbfbafcf6ddeced2214dc2e823741
https://pubmed.ncbi.nlm.nih.gov/34731098
https://pubmed.ncbi.nlm.nih.gov/34731098
Autor:
Josefine Slater, Daniel Kjær, Arunas Pikelis, Torben Ingemann Petersen, M. B. Nielsen, Birgitte Jul Kiil, Sune Brinck Erichsen, Marianne Nordsmark, Niels Katballe
Publikováno v:
Erichsen, S B, Slater, J, Kiil, B J, Petersen, T I, Katballe, N, Nielsen, M B, Pikelis, A, Nordsmark, M & Kjaer, D 2022, ' Oncological results and morbidity following intended curative resection and free jejunal graft reconstruction of cervical esophageal cancer : a retrospective Danish consecutive cohort study ', Diseases of the Esophagus (Online), vol. 35, no. 3, doab048 . https://doi.org/10.1093/dote/doab048
Summary Background The role of surgery in treatment of locally advanced cervical esophageal cancer (CEC) remains debated. In the European and American treatment guidelines, definitive chemoradiotherapy (dCRT) is preferred over surgery, while in the D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b7443e9e99df352a6a796c6acadea9
https://doi.org/10.1093/dote/doab048
https://doi.org/10.1093/dote/doab048
Autor:
Mathias Alrø Fichtner Bendtsen, Kjeld Søballe, Andrea René Jørgensen, Mats Bue, Pelle Hanberg, Eva Greibe, Maiken Stilling, Nis Pedersen Jørgensen, Josefine Slater
Publikováno v:
Journal of Antimicrobial Chemotherapy.
Background Pyogenic spondylodiscitis remains a therapeutic challenge, as demonstrated by divergent treatment guidelines. The combination of moxifloxacin and rifampicin may be an attractive treatment option for cases caused by staphylococci; however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e99f64b160622567a486991fa08c5c6e
https://doi.org/10.1093/jac/dkaa153
https://doi.org/10.1093/jac/dkaa153
Autor:
Josefine, Slater, Pelle, Hanberg, Mathias Alrø Fichtner, Bendtsen, Andrea René, Jørgensen, Eva, Greibe, Kjeld, Søballe, Mats, Bue, Nis, Pedersen Jørgensen, Maiken, Stilling
Publikováno v:
The Journal of antimicrobial chemotherapy. 75(8)
Pyogenic spondylodiscitis remains a therapeutic challenge, as demonstrated by divergent treatment guidelines. The combination of moxifloxacin and rifampicin may be an attractive treatment option for cases caused by staphylococci; however, previous st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84f15115f41791d7c8408b2a22d99d62
https://pubmed.ncbi.nlm.nih.gov/32413120
https://pubmed.ncbi.nlm.nih.gov/32413120
Autor:
Bettina Bundgaard, Per Höllsberg, Mette Biltoft, Bjarne Kuno Møller, Josefine Slater, Aida S. Hansen
Publikováno v:
Immunology Letters
Hansen, A S, Slater, J, Biltoft, M, Bundgaard, B B, Møller, B K & Höllsberg, P 2018, ' CD46 is a potent co-stimulatory receptor for expansion of human IFN-γ-producing CD8+ T cells ', Immunology Letters, vol. 200, pp. 26-32 . https://doi.org/10.1016/j.imlet.2018.06.003
Hansen, A S, Slater, J, Biltoft, M, Bundgaard, B B, Møller, B K & Höllsberg, P 2018, ' CD46 is a potent co-stimulatory receptor for expansion of human IFN-γ-producing CD8+ T cells ', Immunology Letters, vol. 200, pp. 26-32 . https://doi.org/10.1016/j.imlet.2018.06.003
Highlights • Activation of CD46 induces rapid down-modulation of CD46 expression on the surface of CD8+ T cells. • CD46 co-stimulation potently induces CD8+ T cell proliferation. • CD46 co-stimulation does not induce a switch to IL-10 productio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bcab20691da84aa1d6d0a5ac3c8123e
https://pubmed.ncbi.nlm.nih.gov/29902483
https://pubmed.ncbi.nlm.nih.gov/29902483