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pro vyhledávání: '"Josefine Sandström"'
Autor:
Josefine Sandström, Jens Bomanson, Gizeh Pérez-Tenorio, Carolin Jönsson, Bo Nordenskjöld, Tommy Fornander, Linda S. Lindström, Olle Stål
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract GATA binding protein 3 (GATA3) is essential for normal development of the mammary gland and associated with ER-positive breast cancer. Loss of GATA3 has been associated with epithelial-mesenchymal transition (EMT) in experimental studies. We
Externí odkaz:
https://doaj.org/article/5489900ba9c54810a4ba6d86094baf2b
Autor:
Carolin Jönsson, Zeinab Alkashaf, Josefine Sandström, Annelie Johansson, Tommy Fornander, Linda S. Lindström, Gizeh Perez Tenorio
Publikováno v:
Cancer Research. 83:B027-B027
The PIK3CA gene, encoding the p110α catalytic subunit of PI 3-kinase (PI3K), is mutated in more than 30% of breast cancers. Most mutations concentrate to the hotspots E542K and E545K and H1047R and are associated with hyperactivation of the phosphat