Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Josefine Reber"'
Autor:
Konxhe Kulaj, Alexandra Harger, Michaela Bauer, Özüm S. Caliskan, Tilak Kumar Gupta, Dapi Menglin Chiang, Edward Milbank, Josefine Reber, Angelos Karlas, Petra Kotzbeck, David N. Sailer, Francesco Volta, Dominik Lutter, Sneha Prakash, Juliane Merl-Pham, Vasilis Ntziachristos, Hans Hauner, Michael W. Pfaffl, Matthias H. Tschöp, Timo D. Müller, Stefanie M. Hauck, Benjamin D. Engel, Jantje M. Gerdes, Paul T. Pfluger, Natalie Krahmer, Kerstin Stemmer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Extracellular vesicles (EVs) convey inter-organ communication in health and disease. Here, the authors report that adipocyte-derived EVs isolated from insulin-resistant obese but not lean male mice stimulate insulin secretion via the targeted transfe
Externí odkaz:
https://doaj.org/article/7a980c15ae974d7993862a2be969cbb9
Autor:
Nikolina-Alexia Fasoula, Angelos Karlas, Olga Prokopchuk, Nikoletta Katsouli, Michail Bariotakis, Evangelos Liapis, Anna Goetz, Michael Kallmayer, Josefine Reber, Alexander Novotny, Helmut Friess, Marc Ringelhan, Roland Schmid, Hans-Henning Eckstein, Susanna Hofmann, Vasilis Ntziachristos
Publikováno v:
Photoacoustics, Vol 29, Iss , Pp 100454- (2023)
Hepatic steatosis is characterized by intrahepatic lipid accumulation and may lead to irreversible liver damage if untreated. Here, we investigate whether multispectral optoacoustic tomography (MSOT) can offer label-free detection of liver lipid cont
Externí odkaz:
https://doaj.org/article/1ac5d72552684ca7990341729433c36a
Autor:
Angelos Karlas, Nikolina-Alexia Fasoula, Korbinian Paul-Yuan, Josefine Reber, Michael Kallmayer, Dmitry Bozhko, Markus Seeger, Hans-Henning Eckstein, Moritz Wildgruber, Vasilis Ntziachristos
Publikováno v:
Photoacoustics, Vol 14, Iss , Pp 19-30 (2019)
Imaging has become an indispensable tool in the research and clinical management of cardiovascular disease (CVD). An array of imaging technologies is considered for CVD diagnostics and therapeutic assessment, ranging from ultrasonography, X-ray compu
Externí odkaz:
https://doaj.org/article/9c9620f11154425a84f067265b759aa4
Autor:
Hui Wang, Monja Willershäuser, Angelos Karlas, Dimitris Gorpas, Josefine Reber, Vasilis Ntziachristos, Stefanie Maurer, Tobias Fromme, Yongguo Li, Martin Klingenspor
Publikováno v:
Molecular Metabolism, Vol 20, Iss , Pp 14-27 (2019)
Objectives: Brown adipose tissue (BAT) dissipates nutritional energy as heat through uncoupling protein 1 (UCP1). The discovery of functional BAT in healthy adult humans has promoted the search for pharmacological interventions to recruit and activat
Externí odkaz:
https://doaj.org/article/0df01d6deaec48268d968eef91d6b988
Autor:
Christoffer Clemmensen, Sigrid Jall, Maximilian Kleinert, Carmelo Quarta, Tim Gruber, Josefine Reber, Stephan Sachs, Katrin Fischer, Annette Feuchtinger, Angelos Karlas, Stephanie E. Simonds, Gerald Grandl, Daniela Loher, Eva Sanchez-Quant, Susanne Keipert, Martin Jastroch, Susanna M. Hofmann, Emmani B. M. Nascimento, Patrick Schrauwen, Vasilis Ntziachristos, Michael A. Cowley, Brian Finan, Timo D. Müller, Matthias H. Tschöp
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Tobacco smoking and cold exposure are environmental modulators of human energy metabolism suppressing appetite and increasing energy expenditure, respectively. Here, the authors develop a novel pharmacological strategy in which they simultaneously mi
Externí odkaz:
https://doaj.org/article/daba42e8bc934c15ab731e4faf7ff42c
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1696 (2021)
Breast cancer is a complex tumor type involving many biological processes. Most chemotherapeutic agents exert their antitumoral effects by rapid induction of apoptosis. Another main feature of breast cancer is hypoxia, which may drive malignant progr
Externí odkaz:
https://doaj.org/article/ed9b1c86cc634aadbe6dd83fae600f46
Autor:
Cristina Müller, Josefine Reber, Stephanie Haller, Holger Dorrer, Ulli Köster, Karl Johnston, Konstantin Zhernosekov, Andreas Türler, Roger Schibli
Publikováno v:
Pharmaceuticals, Vol 7, Iss 3, Pp 353-365 (2014)
Terbium-149 is among the most interesting therapeutic nuclides for medical applications. It decays by emission of short-range α-particles (Eα = 3.967 MeV) with a half-life of 4.12 h. The goal of this study was to investigate the anticancer efficacy
Externí odkaz:
https://doaj.org/article/6ae57cd8292f47358c13172755137b09
Autor:
Christoffer Clemmensen, Sigrid Jall, Maximilian Kleinert, Carmelo Quarta, Tim Gruber, Josefine Reber, Stephan Sachs, Katrin Fischer, Annette Feuchtinger, Angelos Karlas, Stephanie E. Simonds, Gerald Grandl, Daniela Loher, Eva Sanchez-Quant, Susanne Keipert, Martin Jastroch, Susanna M. Hofmann, Emmani B. M. Nascimento, Patrick Schrauwen, Vasilis Ntziachristos, Michael A. Cowley, Brian Finan, Timo D. Müller, Matthias H. Tschöp
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
In the original PDF version of this article, affiliation 1, ‘Institute for Diabetes and Obesity, Helmholtz Diabetes Center (HDC), Helmholtz Zentrum Muenchen & German Center for Diabetes Research (DZD), Neuherberg, Germany’, was incorrectly given
Externí odkaz:
https://doaj.org/article/ae33b6c3d2134fc19b2fa65e3a0a054d
PDF - 94KB, Table S1: Complete biodistribution data obtained with 177Lu-EC0800 in KB tumor bearing nude mice. Table S2: Combination indices for 177Lu-EC0800 and PMX determined in vitro using KB and IGROV-1 tumor cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a50e350c519315d658533cbad11d3ac
https://doi.org/10.1158/1535-7163.22498294.v1
https://doi.org/10.1158/1535-7163.22498294.v1
PDF - 569KB, Figure S1: Chemical structures of the compounds applied in this study. Figure S2: Results of the internalization studies of 177Lu-EC0800 performed with FR-positive and FR-negative tumor cell lines Figure S3: Results of a clonogenic assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3618cc2a01ed805989e6fcf65b9c8bee
https://doi.org/10.1158/1535-7163.22498300.v1
https://doi.org/10.1158/1535-7163.22498300.v1