Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Josefine Olsen"'
Autor:
Christian Schnaars, Adriana Magalhaes Santos Andresen, Silje Lauksund, Christopher Fröhlich, Pal Rongved, Ole Andreas Økstad, Sandra Huber, Susann Skagseth, Tor Gjøen, Ørjan Samuelsen, Adam Heikal, Hanna-Kirsti S. Leiros, Ove Alexander Høgmoen Åstrand, Annette Bayer, Geir Kildahl-Andersen, Trine Josefine Olsen Carlsen, Sarah Finke
Publikováno v:
Antimicrobial Agents and Chemotherapy
Carbapenem-resistant Gram-negative pathogens are a critical public health threat and there is an urgent need for new treatments. Carbapenemases (β-lactamases able to inactivate carbapenems) have been identified in both serine β-lactamase (SBL) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be70d5ec4329bdb54e632d65b712aa9
https://hdl.handle.net/10037/18642
https://hdl.handle.net/10037/18642
Autor:
Samuelsen, Ørjan, Åstrand, Ove Alexander Høgmoen, Frøhlich, Christopher, Heikal, Adam, Skagseth, Susann, Carlsen, Trine Josefine Olsen, Leiros, Hanna-Kirsti S., Bayer, Annette, Schnaars, Christian, Kildahl-andersen, Geir, Lauksund, Silje, Finke, Sarah, Huber, Sandra, Gjøen, Tor, Andresen, Adriana Magalhaes Santos, Økstad, Ole Andreas, Rongved, Pål
Publikováno v:
Samuelsen Ø, Åstrand OAHÅ, Frøhlich CF, Heikal A, Skagseth S, Carlsen TJO, Leiros H, Bayer A, Schnaars C, Kildahl-andersen G, Lauksund R S, Finke S, Huber SH, Gjøen T, Andresen AMS, Økstad OA, Rongved PR. ZN148 Is a Modular Synthetic Metallo-beta-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo. Antimicrobial Agents and Chemotherapy. 2020
Externí odkaz:
https://hdl.handle.net/10037/18642
Autor:
Birgit Helene Berg Nesheim, Ane Molden Thomassen, Tony Christopeit, Hanna-Kirsti S. Leiros, Johan Isaksson, Bjarte Aarmo Lund, Trine Josefine Olsen Carlsen
Publikováno v:
The FEBS journal. 285(22)
Many class D β-lactamases form dimers in solution. The functional basis of the dimerization of OXA-48-like class D β-lactamases is not known, but in order to understand the structural requirements for dimerization of OXA-48, we have characterized t
Publikováno v:
Journal of Medicinal Chemistry. 58:8671-8682
Accepted manuscript version. Published version at http://doi.org/10.1021/acs.jmedchem.5b01289. Metallo-β-lactamase (MBL) inhibitors can restore the function of carbapenem antibiotics and therefore help to treat infections of antibiotic resistant bac
Autor:
Ane Molden Thomassen, Trine Josefine Olsen Carlsen, Hanna-Kirsti S. Leiros, Bjarte Aarmo Lund
The first crystal structures of the class D β-lactamases OXA-181 and OXA-245 were determined to 2.05 and 2.20 Å resolution, respectively; in addition, the structure of a new crystal form of OXA-163 was resolved to 2.07 Å resolution. All of these e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e278035fda1f81970b90d9562346ac7
https://europepmc.org/articles/PMC5633926/
https://europepmc.org/articles/PMC5633926/
Autor:
Lund, Bjarte Aarmo, Thomassen, Ane Molden, Carlsen, Trine Josefine Olsen, Leiros, Hanna-Kirsti S.
Publikováno v:
Lund BA, Thomassen AM, Carlsen TJO, Leiros HKS. Structure, activity and thermostability investigations of OXA-163, OXA-181 and OXA-245 using biochemical analysis, crystal structures and differential scanning calorimetry analysis. Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 2017;73(10):579-587
Externí odkaz:
https://hdl.handle.net/10037/11919
Akademický článek
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Autor:
Arkady Babchenko, Josefine Olsen
Publikováno v:
Index on Censorship. 37:116-120
Autor:
Josefine Olsen, Viktor Shenderovich
Publikováno v:
Index on Censorship. 37:48-57
Autor:
Natalia Rostova, Josefine Olsen
Publikováno v:
Index on Censorship. 37:155-163