Potentiation of Drug Toxicity through Virus Latency Reversal Promotes Preferential Elimination of HIV Infected Cells

Autor: Thanh Tung Truong, Manuel Hayn, Camilla Kaas Frich, Lia‐Raluca Olari, Lucy Kate Ladefoged, Morten T. Jarlstad Olesen, Josefine H. Jakobsen, Cherie K. Lunabjerg‐Vestergaard, Birgit Schiøtt, Jan Münch, Alexander N. Zelikin

Publikováno v: Truong, T T, Hayn, M, Frich, C K, Olari, L-R, Ladefoged, L K, Olesen, M T J, Jakobsen, J H, Lunabjerg-Vestergaard, C K, Schiøtt, B, Münch, J & Zelikin, A N 2022, ' Potentiation of Drug Toxicity through Virus Latency Reversal Promotes Preferential Elimination of HIV Infected Cells ', Advanced Therapeutics, vol. 5, no. 11, 2200113 . https://doi.org/10.1002/adtp.202200113

Eliminating latently infected cells is a highly challenging, indispensable step toward the cure for HIV/AIDS. Hypothesis put forward herein is that the unique HIV protease cut site (Phe-Pro) can be reconstructed using a potent inhibitor of tubulin po

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