Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Josefina Nordström"'
In this study, the question of how fragmentation and deformation of granules during compression can be linked to the tableting performance of dry granulated powders is addressed. Granulated powders of a systematically varied composition of a plastic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bfa29e1b06b6a49fd335a375b68f825
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-483758
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-483758
Publikováno v:
Chemical Engineering Research and Design. 110:183-191
The issue of accurate derivation of a granule yield stress by the traditional procedure using the Heckel equation in addition to the Kawakita and Adams equations has been addressed. The accuracy of the derived parameters was assessed from comparison
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48c654b248e86588968302c40f77c28d
https://doi.org/10.1016/j.cherd.2016.01.028
https://doi.org/10.1016/j.cherd.2016.01.028
Autor:
Göran Alderborn, Josefina Nordström
Publikováno v:
Journal of Pharmaceutical Sciences. 104:2029-2039
The aim of this study was to investigate the role of porosity on the compression behavior and tablet tensile strength for granules produced by a dry granulation procedure. Microcrystalline cellulose was used as a typical pharmaceutical excipient and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7adc6a72782f2c9f74e7efb25f08c4
https://doi.org/10.1002/jps.24439
https://doi.org/10.1002/jps.24439
Publikováno v:
International journal of pharmaceutics. 540(1-2)
Compressibility and tablet forming ability (compactibility) of bimodal mixtures of differently sized granules formed from microcrystalline cellulose were studied experimentally and numerically with the discrete element method (DEM). Compression data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74be2662c619da4b6e8cb46a68f95a1
https://pubmed.ncbi.nlm.nih.gov/29425765
https://pubmed.ncbi.nlm.nih.gov/29425765
Publikováno v:
International Journal of Pharmaceutics. 453:295-299
The purpose of the research was to introduce a procedure to derive a powder compression parameter (EM A) representing particle yield stress using an effective medium equation and to compare the EM A parameter with the Heckel compression parameter (1/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186899049fb8e60e0517c2c192902b0e
https://doi.org/10.1016/j.ijpharm.2013.06.040
https://doi.org/10.1016/j.ijpharm.2013.06.040
Publikováno v:
International Journal of Pharmaceutics. 442:3-12
The effect of degree of compression on the evolution of tablet microstructure and bond probability during compression of granular solids has been studied. Microcrystalline cellulose pellets of low (about 11%) and of high (about 32%) porosity were use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc531a19d72f0608c53275b635dc4d7
https://doi.org/10.1016/j.ijpharm.2012.08.011
https://doi.org/10.1016/j.ijpharm.2012.08.011
Publikováno v:
International journal of pharmaceutics. 518(1-2)
The aim of this study was to investigate the structural impact of the nanofiller incorporation on the powder compression mechanics of spray-dried lactose. The lactose was co-spray-dried with three different nanofillers, that is, cellulose nanocrystal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5cb77e90939ba6a731c4cdee88f4f9
https://pubmed.ncbi.nlm.nih.gov/28007544
https://pubmed.ncbi.nlm.nih.gov/28007544
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 75:425-435
The current work aims to investigate whether a multivariate statistical approach could reveal latent structures in compression data and group powders with respect to their compression behavior in a way that is consistent with an earlier proposed clas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd589ce54e013021e0cc600a72b3427
https://doi.org/10.1016/j.ejpb.2010.04.006
https://doi.org/10.1016/j.ejpb.2010.04.006
Publikováno v:
Powder Technology. 194:228-232
A simplified model for confined compression of granular materials is considered, which idealizes the collection of particles as a (central) force network. Applying an effective-medium procedure, an equation with micromechanically well-defined paramet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32b0d9c4e086ded782b2734870501fbe
https://doi.org/10.1016/j.powtec.2009.04.012
https://doi.org/10.1016/j.powtec.2009.04.012
Publikováno v:
Journal of Pharmaceutical Sciences. 98:1053-1063
In this article, the effect of original particle size on the Kawakita parameters, denoted a and b, has been studied using four model materials of different compression mechanics. It was found that fine powders, possibly showing significant particle r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4fce896c08c61a001a7eee7c053b6d
https://doi.org/10.1002/jps.21488
https://doi.org/10.1002/jps.21488