Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Josefin Skogsberg"'
Autor:
Benjamin S. Glicksberg, Letizia Amadori, Nicholas K. Akers, Katyayani Sukhavasi, Oscar Franzén, Li Li, Gillian M. Belbin, Kristin L. Akers, Khader Shameer, Marcus A. Badgeley, Kipp W. Johnson, Ben Readhead, Bruce J. Darrow, Eimear E. Kenny, Christer Betsholtz, Raili Ermel, Josefin Skogsberg, Arno Ruusalepp, Eric E. Schadt, Joel T. Dudley, Hongxia Ren, Jason C. Kovacic, Chiara Giannarelli, Shuyu D. Li, Johan L. M. Björkegren, Rong Chen
Publikováno v:
BMC Medical Genomics, Vol 12, Iss S6, Pp 1-16 (2019)
Abstract Background Genetic loss-of-function variants (LoFs) associated with disease traits are increasingly recognized as critical evidence for the selection of therapeutic targets. We integrated the analysis of genetic and clinical data from 10,511
Externí odkaz:
https://doaj.org/article/a76b99477ddb49caaac1147906552dfc
Autor:
Oscar Franzén, Raili Ermel, Katyayani Sukhavasi, Rajeev Jain, Anamika Jain, Christer Betsholtz, Chiara Giannarelli, Jason C. Kovacic, Arno Ruusalepp, Josefin Skogsberg, Ke Hao, Eric E. Schadt, Johan L.M. Björkegren
Publikováno v:
PeerJ, Vol 6, p e4466 (2018)
RNA editing modifies transcripts and may alter their regulation or function. In humans, the most common modification is adenosine to inosine (A-to-I). We examined the global characteristics of RNA editing in 4,301 human tissue samples. More than 1.6
Externí odkaz:
https://doaj.org/article/400c7a24f8b34d1b987fdf4d12315de7
Autor:
Benjamin S. Glicksberg, Letizia Amadori, Nicholas K. Akers, Katyayani Sukhavasi, Oscar Franzén, Li Li, Gillian M. Belbin, Kristin L. Ayers, Khader Shameer, Marcus A. Badgeley, Kipp W. Johnson, Ben Readhead, Bruce J. Darrow, Eimear E. Kenny, Christer Betsholtz, Raili Ermel, Josefin Skogsberg, Arno Ruusalepp, Eric E. Schadt, Joel T. Dudley, Hongxia Ren, Jason C. Kovacic, Chiara Giannarelli, Shuyu D. Li, Johan L. M. Björkegren, Rong Chen
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-1 (2019)
Externí odkaz:
https://doaj.org/article/4821428476ee4beaa78f0a9545cce053
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 2, Pp 267-277 (2007)
Together with computational analysis and modeling, the development of whole-genome measurement technologies holds the potential to fundamentally change research on complex disorders such as coronary artery disease. With these tools, the stage has bee
Externí odkaz:
https://doaj.org/article/25b8566c0a8641c887c72580320a074a
Autor:
Johan L M Björkegren, Sara Hägg, Husain A Talukdar, Hassan Foroughi Asl, Rajeev K Jain, Cecilia Cedergren, Ming-Mei Shang, Aránzazu Rossignoli, Rabbe Takolander, Olle Melander, Anders Hamsten, Tom Michoel, Josefin Skogsberg
Publikováno v:
PLoS Genetics, Vol 10, Iss 2, p e1004201 (2014)
Plasma cholesterol lowering (PCL) slows and sometimes prevents progression of atherosclerosis and may even lead to regression. Little is known about how molecular processes in the atherosclerotic arterial wall respond to PCL and modify responses to a
Externí odkaz:
https://doaj.org/article/91a3a9e28f764aec98649bad00f3c1b0
Autor:
Sara Hägg, Mehran Salehpour, Peri Noori, Jesper Lundström, Göran Possnert, Rabbe Takolander, Peter Konrad, Stefan Rosfors, Arno Ruusalepp, Josefin Skogsberg, Jesper Tegnér, Johan Björkegren
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18248 (2011)
BACKGROUND: The stability of atherosclerotic plaques determines the risk for rupture, which may lead to thrombus formation and potentially severe clinical complications such as myocardial infarction and stroke. Although the rate of plaque formation m
Externí odkaz:
https://doaj.org/article/6fab7ebcabe441bd889c779d333c205a
Autor:
Sara Hägg, Josefin Skogsberg, Jesper Lundström, Peri Noori, Roland Nilsson, Hua Zhong, Shohreh Maleki, Ming-Mei Shang, Björn Brinne, Maria Bradshaw, Vladimir B Bajic, Ann Samnegård, Angela Silveira, Lee M Kaplan, Bruna Gigante, Karin Leander, Ulf de Faire, Stefan Rosfors, Ulf Lockowandt, Jan Liska, Peter Konrad, Rabbe Takolander, Anders Franco-Cereceda, Eric E Schadt, Torbjörn Ivert, Anders Hamsten, Jesper Tegnér, Johan Björkegren
Publikováno v:
PLoS Genetics, Vol 5, Iss 12, p e1000754 (2009)
Environmental exposures filtered through the genetic make-up of each individual alter the transcriptional repertoire in organs central to metabolic homeostasis, thereby affecting arterial lipid accumulation, inflammation, and the development of coron
Externí odkaz:
https://doaj.org/article/a36a7f46d91547e2bc0f1a6cf6f69acd
Transcriptional profiling uncovers a network of cholesterol-responsive atherosclerosis target genes.
Autor:
Josefin Skogsberg, Jesper Lundström, Alexander Kovacs, Roland Nilsson, Peri Noori, Shohreh Maleki, Marina Köhler, Anders Hamsten, Jesper Tegnér, Johan Björkegren
Publikováno v:
PLoS Genetics, Vol 4, Iss 3, p e1000036 (2008)
Despite the well-documented effects of plasma lipid lowering regimes halting atherosclerosis lesion development and reducing morbidity and mortality of coronary artery disease and stroke, the transcriptional response in the atherosclerotic lesion med
Externí odkaz:
https://doaj.org/article/0628a124023e4368ae1442558fe68a23
Autor:
Josefin Skogsberg, Andrea Dicker, Mikael Rydén, Gaby Aström, Roland Nilsson, Hasanuzzaman Bhuiyan, Sigurd Vitols, Aline Mairal, Dominique Langin, Peteris Alberts, Erik Walum, Jesper Tegnér, Anders Hamsten, Peter Arner, Johan Björkegren
Publikováno v:
PLoS ONE, Vol 3, Iss 11, p e3771 (2008)
BackgroundFree fatty acids released from adipose tissue affect the synthesis of apolipoprotein B-containing lipoproteins and glucose metabolism in the liver. Whether there also exists a reciprocal metabolic arm affecting energy metabolism in white ad
Externí odkaz:
https://doaj.org/article/18acd09f2f934361b3faaae2d2d5215a
Autor:
Sofie Persson, Kristoffer Nilsson, Kristina Karlsdotter, Josefin Skogsberg, Staffan Gustavsson, Johan Jendle, Katarina Steen Carlsson
Publikováno v:
Diabetes, Obesity and Metabolism. 25:726-734
To assess hospital-based care, work absence, associated costs, and mortality in patients with type 2 diabetes with and without established cardiovascular disease (eCVD) compared to matched controls.In a population-based cohort study, we analysed indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7237bd825acbc891d5f455ef3cf93341
https://doi.org/10.1111/dom.14919
https://doi.org/10.1111/dom.14919