Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Josefin M. E. Forslund"'
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629215
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cf6840c8b780e5e477c941dddb64fa4
https://doi.org/10.1007/978-1-0716-2922-2_15
https://doi.org/10.1007/978-1-0716-2922-2_15
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007315 (2018)
Ribonucleotides (rNMPs) are frequently incorporated during replication or repair by DNA polymerases and failure to remove them leads to instability of nuclear DNA (nDNA). Conversely, rNMPs appear to be relatively well-tolerated in mitochondrial DNA (
Externí odkaz:
https://doaj.org/article/ff328a5568ff4d1db9e664e303f9af7c
Autor:
Luis Blanco, Annika Pfeiffer, Sjoerd Wanrooij, Gorazd Stojkovič, Josefin M. E. Forslund, Natalie Al-Furoukh, Jaakko L. O. Pohjoismäki, Steffi Goffart, Gustavo Carvalho, Rubén Torregrosa-Muñumer
Publikováno v:
Proceedings of the National Academy of Sciences. 114:11398-11403
Significance Failure to maintain mtDNA integrity can lead to a wide variety of neuromuscular disorders. Despite its central role in the development of these disorders, many mechanistic details of mtDNA maintenance are still unclear. In the present wo
Autor:
Rubén Torregrosa-Muñumer, Jaakko L. O. Pohjoismäki, Steffi Goffart, Sjoerd Wanrooij, Josefin M. E. Forslund
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 40(9)
Mammalian mitochondrial DNA (mtDNA) replication and repair have been studied intensively for the last 50 years. Although recently advances in elucidating the molecular mechanisms of mtDNA maintenance and the proteins involved in these have been made,
Autor:
Gorazd Stojkovič, Sjoerd Wanrooij, Josefin M. E. Forslund, Annika Pfeiffer, Pauline H. Wanrooij
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 14, Iss 3, p e1007315 (2018)
PLoS Genetics, Vol 14, Iss 3, p e1007315 (2018)
Ribonucleotides (rNMPs) are frequently incorporated during replication or repair by DNA polymerases and failure to remove them leads to instability of nuclear DNA (nDNA). Conversely, rNMPs appear to be relatively well-tolerated in mitochondrial DNA (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e913e52aaf7cdbc0a86360e4e568f8e0
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-146802
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-146802
Autor:
Gorazd Stojkovič, Alena V. Makarova, Sjoerd Wanrooij, Josefin M. E. Forslund, Paulina H. Wanrooij, Peter M. J. Burgers
Publikováno v:
Scientific Reports
Oxidative stress is capable of causing damage to various cellular constituents, including DNA. There is however limited knowledge on how oxidative stress influences mitochondrial DNA and its replication. Here, we have used purified mtDNA replication