Chemokine profile in the serum of patients with leptospirosis

Autor: Iago H. de Miranda Mariano, Roberta M. Blanco, Camila Eulalio de Souza, Geovanna Silva de Freitas, Paulo Lee Ho, Elizabeth A. L. Martins, Eliete C. Romero, Josefa B. da Silva

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)

IntroductionLeptospirosis is a global zoonosis that affects more than one million people per year, with a lethality rate of approximately 15%. Chemokines are crucial in the immune response against Leptospira, recruiting leukocytes to the site of infe

Externí odkaz: https://doaj.org/article/7593d82116294d2aa480e8f14b080461

New strategies for Leptospira vaccine development based on LPS removal.

Autor: Fabiana Lauretti-Ferreira, Paloma L D Silva, Naiara M Alcântara, Bruna F Silva, Isabele Grabher, Gisele O Souza, Erika Nakajima, Milena A Akamatsu, Silvio A Vasconcellos, Patricia A E Abreu, Eneas Carvalho, Elizabeth A L Martins, Paulo L Ho, Josefa B da Silva

Publikováno v: PLoS ONE, Vol 15, Iss 3, p e0230460 (2020)

Pathogenic spirochetes from genus Leptospira are etiologic agents of leptospirosis. Cellular vaccines against Leptospira infection often elicit mainly response against the LPS antigen of the serovars present in the formulation. There is no suitable p

Externí odkaz: https://doaj.org/article/b0ebd28d404149d0909bf7e667f8f5e1

Phagocytosis of Leptospira by leukocytes from mice with different susceptibility to leptospirosis and possible role of chemokines

Autor: Ambart E. Covarrubias, Josefa B. da Silva, Elizabeth A. L. Martins, Eneas Carvalho, Paulo Lee Ho, Paloma Luiza Duarte da Silva, Renata M. A. da Costa, Fabiana Lauretti-Ferreira, Swiany Silveira Lima, Marcelo De Franco, Maiara Caldas de Lima

Publikováno v: BMC Microbiology, Vol 19, Iss 1, Pp 1-10 (2019)
BMC Microbiology

Background Leptospirosis is a widespread zoonosis caused by pathogenic prokaryotic microbes of the genus Leptospira. Although there are several reports in the literature, host-pathogen interaction is still poorly understood. The role of chemokine exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a76d7b8fa487a14beaf3cd2f47fcad9
http://link.springer.com/article/10.1186/s12866-018-1371-9

New strategies for Leptospira vaccine development based on LPS removal

Autor: Naiara M. Alcântara, Elizabeth A. L. Martins, Fabiana Lauretti-Ferreira, Patrícia Antonia Estima Abreu, Josefa B. da Silva, Milena Apetito Akamatsu, Gisele Oliveira de Souza, Eneas Carvalho, Erika Nakajima, Paloma Luiza Duarte da Silva, Paulo Lee Ho, Bruna Fernanda da Silva, Isabele Grabher, Silvio Arruda Vasconcellos

Publikováno v: PLoS ONE
PLoS ONE, Vol 15, Iss 3, p e0230460 (2020)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Pathogenic spirochetes from genus Leptospira are etiologic agents of leptospirosis. Cellular vaccines against Leptospira infection often elicit mainly response against the LPS antigen of the serovars present in the formulation. There is no suitable p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e61b37ce24cd00d5bbfa6a43ebca34
http://europepmc.org/articles/PMC7100938

Chemokine expression profiles in liver and kidney of mice with different susceptibilities to leptospirosis

Autor: Eneas Carvalho, Renata M. A. da Costa, Paulo Lee Ho, Josefa B. da Silva, Erika Nakajima, Paloma Luiza Duarte da Silva, Elizabeth A. L. Martins

Publikováno v: Microbial Pathogenesis. 149:104580

Leptospirosis is a global disease that affects humans and animals, impacting public health and the economy. The symptoms caused by Leptospira infection can vary from mild to severe, affecting liver, lungs, and kidneys. The host-pathogen interaction i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e80a218f0b305b0ea7f622d9db13058
https://doi.org/10.1016/j.micpath.2020.104580