Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Josef Srovnal"'
Autor:
Emil Berta, Josef Srovnal, Petr Dytrych, Jan Bruthans, Jitka Ulrichova, Petr Prasil, Lubomir Vecera, Tomas Gabrhelik, Benjamin Tolmaci, Josef Dusa, Jan Maca, Michelle Mazancova, Filip Haiduk, Martin Kutej, Peter Ihnat, Pavel Michalek, Marian Hajduch
Publikováno v:
BMC Anesthesiology, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Opioids and epidural analgesia are a mainstay of perioperative analgesia but their influence on cancer recurrence remains unclear. Based on retrospective data, we found that cancer recurrence following colorectal cancer surgery co
Externí odkaz:
https://doaj.org/article/8193a89a583c4cdea537cf24eeeb7c67
Autor:
Pavel Stejskal, Hani Goodarzi, Josef Srovnal, Marián Hajdúch, Laura J. van ’t Veer, Mark Jesus M. Magbanua
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-21 (2023)
Abstract Background Despite advances in early detection and therapies, cancer is still one of the most common causes of death worldwide. Since each tumor is unique, there is a need to implement personalized care and develop robust tools for monitorin
Externí odkaz:
https://doaj.org/article/5f15669e1e44477eb4ccfa9566f2c012
Autor:
Andrea Stefekova, Pavlina Capkova, Zuzana Capkova, Vaclava Curtisova, Josef Srovnal, Enkhjargalan Mracka, Eva Klaskova, Martin Prochazka
Publikováno v:
Biomedical Papers, Vol 166, Iss 2, Pp 187-194 (2022)
Aims. The aim of this retrospective study was to determine the detection rate of the pathogenic copy number variants (CNVs) in a cohort of 33 foetuses - 32 with CHD (congenital heart defects) and 1 with kidney defect, after exclusion of common aneupl
Externí odkaz:
https://doaj.org/article/d7895605c7434adb8be9ddb11e1edc9d
Autor:
Lubomir Vecera, Petr Prasil, Josef Srovnal, Emil Berta, Monika Vidlarova, Tomas Gabrhelik, Pavla Kourilova, Martin Lovecek, Pavel Skalicky, Jozef Skarda, Zdenek Kala, Pavel Michalek, Marian Hajduch
Publikováno v:
Cancers, Vol 15, Iss 16, p 4038 (2023)
Pancreatic cancer (PDAC) has a poor prognosis despite surgical removal and adjuvant therapy. Additionally, the effects of postoperative analgesia with morphine and piritramide on survival among PDAC patients are unknown, as are their interactions wit
Externí odkaz:
https://doaj.org/article/43f361d816b04cc9a9df7246f1244004
Autor:
Marketa Koleckova, Jiri Ehrmann, Jan Bouchal, Maria Janikova, Aneta Brisudova, Josef Srovnal, Katerina Staffova, Marek Svoboda, Ondrej Slaby, Lenka Radova, Katherine Vomackova, Bohuslav Melichar, Lucia Veverkova, Zdenek Kolar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Triple negative breast cancers (TNBC) are a morphologically and genetically heterogeneous group of breast cancers with uncertain prediction of biological behavior and response to therapy. Epithelial to mesenchymal transition (EMT) is a dynam
Externí odkaz:
https://doaj.org/article/99a59eb6c6f140ffb0a01a8eea6e2648
Autor:
Monika Vidlarova, Alona Rehulkova, Pavel Stejskal, Andrea Prokopova, Hanus Slavik, Marian Hajduch, Josef Srovnal
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3902 (2023)
Circulating tumor cells (CTCs) are released from primary tumors and transported through the body via blood or lymphatic vessels before settling to form micrometastases under suitable conditions. Accordingly, several studies have identified CTCs as a
Externí odkaz:
https://doaj.org/article/1ad805bb08334d7bb79f830ef43c7b69
Autor:
Zuzana Capkova, Pavlina Capkova, Josef Srovnal, Katerina Staffova, Vera Becvarova, Marie Trkova, Katerina Adamova, Alena Santava, Vaclava Curtisova, Marian Hajduch, Martin Prochazka
Publikováno v:
PeerJ, Vol 7, p e7979 (2019)
Background Autism spectrum disorders (ASD) and intellectual disabilities (ID) are heterogeneous and complex developmental diseases with significant genetic backgrounds and overlaps of genetic susceptibility loci. Copy number variants (CNVs) are known
Externí odkaz:
https://doaj.org/article/53b88db70a184c60b74f990519ae0e3b
Autor:
Pavlina Capkova, Alena Santava, Ivana Markova, Andrea Stefekova, Josef Srovnal, Katerina Staffova, Veronika Durdová
Publikováno v:
Molecular Cytogenetics, Vol 10, Iss 1, Pp 1-8 (2017)
Abstract Background Interstitial microdeletion 14q22q23 is a rare chromosomal syndrome associated with variable defects: microphthalmia/anophthalmia, pituitary anomalies, polydactyly/syndactyly of hands and feet, micrognathia/retrognathia. The report
Externí odkaz:
https://doaj.org/article/e8a5447ac5914ca886a37bbf67342480
Publikováno v:
Molecules, Vol 26, Iss 5, p 1476 (2021)
Polyphenols, secondary metabolites of plants, exhibit different anti-cancer and cytoprotective properties such as anti-radical, anti-angiogenic, anti-inflammation, or cardioprotective. Some of these activities could be linked to modulation of miRNAs
Externí odkaz:
https://doaj.org/article/45a7940e777a421db93cfb7edebaf914
Autor:
Pavlina Capkova, Josef Srovnal, Zuzana Capkova, Katerina Staffova, Vera Becvarova, Marie Trkova, Katerina Adamova, Alena Santava, Vaclava Curtisova, Marian Hajduch, Martin Prochazka
Publikováno v:
PeerJ, Vol 6, p e6183 (2019)
Background Autism spectrum disorder (ASD) is a complex heterogeneous developmental disease with a significant genetic background that is frequently caused by rare copy number variants (CNVs). Microarray-based whole-genome approaches for CNV detection
Externí odkaz:
https://doaj.org/article/7c491a56a7504a0fa1f5977b5c6a5216