Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Josef Platzer"'
Autor:
Francesca Ros, Sonja Offner, Stefan Klostermann, Irmgard Thorey, Helmut Niersbach, Sebastian Breuer, Grit Zarnt, Stefan Lorenz, Juergen Puels, Basile Siewe, Nicole Schueler, Tajana Dragicevic, Dominique Ostler, Imke Hansen-Wester, Valeria Lifke, Brigitte Kaluza, Klaus Kaluza, Wim van Schooten, Roland Buelow, Alain C Tissot, Josef Platzer
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Transgenic animals incorporating human antibody genes are extremely attractive for drug development because they obviate subsequent antibody humanization procedures required for therapeutic translation. Transgenic platforms have previously been estab
Externí odkaz:
https://doaj.org/article/eb4cfd37c8a244a096d64b9303c73a7f
Autor:
Stefan Seeber, Francesca Ros, Irmgard Thorey, Georg Tiefenthaler, Klaus Kaluza, Valeria Lifke, Jens André Alexander Fischer, Stefan Klostermann, Josef Endl, Erhard Kopetzki, Achal Pashine, Basile Siewe, Brigitte Kaluza, Josef Platzer, Sonja Offner
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e86184 (2014)
We have developed a robust platform to generate and functionally characterize rabbit-derived antibodies using B cells from peripheral blood. The rapid high throughput procedure generates a diverse set of antibodies, yet requires only few animals to b
Externí odkaz:
https://doaj.org/article/121e8ae00e8c4eaa9913c08d88a77bdd
Autor:
Tatiana Flisikowska, Irmgard S Thorey, Sonja Offner, Francesca Ros, Valeria Lifke, Bryan Zeitler, Oswald Rottmann, Anna Vincent, Lei Zhang, Shirin Jenkins, Helmut Niersbach, Alexander J Kind, Philip D Gregory, Angelika E Schnieke, Josef Platzer
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21045 (2011)
Rabbits are widely used in biomedical research, yet techniques for their precise genetic modification are lacking. We demonstrate that zinc finger nucleases (ZFNs) introduced into fertilized oocytes can inactivate a chosen gene by mutagenesis and als
Externí odkaz:
https://doaj.org/article/28865b2f7cbb4665ba7b4622b6f2e4fd
Publikováno v:
Review of Economic Dynamics. 41:121-173
This paper presents a toolkit to solve for equilibrium in economies with the effective lower bound (ELB) on the nominal interest rate in a computationally efficient way under a special assumption about the underlying shock process, a two-state Markov
Autor:
Josef Platzer
Publikováno v:
IMF Working Papers. 2023:1
Autor:
Klaus Kaluza, Sebastian Breuer, Roland Buelow, Grit Zarnt, Nicole Schueler, Valeria Lifke, Basile Siewe, Alain Tissot, Irmgard Thorey, Stefan Lorenz, Dominique Ostler, Josef Platzer, Brigitte Kaluza, Francesca Ros, Juergen Puels, Tajana Dragicevic, Sonja Offner, Imke Hansen-Wester, Stefan Klostermann, Helmut Niersbach, Wim Van Schooten
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Transgenic animals incorporating human antibody genes are extremely attractive for drug development because they obviate subsequent antibody humanization procedures required for therapeutic translation. Transgenic platforms have previously been estab
Autor:
Josef Platzer, Marcel Peruffo
Publikováno v:
IMF Working Papers. 2022:1
Autor:
Daphne Atlas, Xiaosong Ma, Jörg Striessnig, Juris Galvanovskis, Erik Renström, Josef Platzer, Patrik Rorsman, Lena Eliasson, Sven Göpel, Michel Trus, Stefanie Obermüller, Sebastian Barg
Publikováno v:
Lund University
ResearcherID
ResearcherID
The association of L-type Ca(2+) channels to the secretory granules and its functional significance to secretion was investigated in mouse pancreatic B cells. Nonstationary fluctuation analysis showed that the B cell is equipped with 25 microM are re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a8c309d512999b7c5fa05b8d2781e1
https://ora.ox.ac.uk/objects/uuid:363a37f7-ea6a-47df-b9e9-29774b4ce2a6
https://ora.ox.ac.uk/objects/uuid:363a37f7-ea6a-47df-b9e9-29774b4ce2a6
Publikováno v:
Archives of Biochemistry and Biophysics. 427:91-100
Interactions of the II-III loop of the voltage-gated Ca(2+) channel alpha(1S) subunit with the Ca(2+) release channel (RyR1) are essential for skeletal-type excitation-contraction (EC) coupling. Here, we characterized the binding site of the monoclon