Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Josef Nemec"'
Publikováno v:
Metals, Vol 13, Iss 11, p 1902 (2023)
Due to their versatile properties, austenitic stainless steels have a wide application potential, including in specific fields, such as the nuclear power industry. ChN35VT steel is a chromium–nickel–tungsten type of steel stabilized by titanium,
Externí odkaz:
https://doaj.org/article/dc8f915ab2174b078159fc515915af78
Publikováno v:
Practical Metallography. 33:198-209
Metric and topological parameters which characterise microstructures of P91 steel after creep have been measured. Analysis has been performed on the same set of micrographs using two different image analysis systems IBAS and DIPS and the resulting cu
Synthesis of homologous peptides using fragment condensation: analogs of an HIV proteinase substrate
Publikováno v:
International journal of peptide and protein research. 38(5)
Two protected peptides Boc-Val-Ser(Bzl)-Gln-Asn-Tyr(BrZ)OH and Boc-Val-Ser(Bzl)-Gln-Asn-Tyr(BrZ)-ProOH were synthesized on a resin substituted by 9-(hydroxymethyl)-2-fluoreneacetic acid. After cleavage with piperidine/DMF, desalting, and activation,
Publikováno v:
The Journal of Organic Chemistry. 39:298-302
Publikováno v:
Biochemistry. 28:4839-4846
Spectroscopic evidence for the radical-mediated metabolism of VP-16, VP-16 catechol, and VP-16 quinone during enzymatic oxidation and autoxidation has been obtained. Autoxidation of the catechol yields the primary semiquinone together with the primar
Publikováno v:
Biochemical and Biophysical Research Communications. 135:215-220
The peroxidative activation of the antitumor drugs, etoposide (VP-16) and teniposide (VM-26), has been studied in vitro. Both of these drugs, in the presence of horseradish peroxidase or prostaglandin synthetase, formed phenoxy radical intermediates.
Autor:
Josef Nemec, Jerry M. Rhoades
Publikováno v:
Nucleosides and Nucleotides. 2:99-112
Conversions of 6-azauridine dialdehyde (1) have been investigated. The reaction of 1 with equimolecular amount of N, N′-diphenylethylenediamine (3) is highly regioselective, leading to the monoimidazolidine 4b (81%) and the bisimidazolidine 6 (10%)
Publikováno v:
Biochemical Pharmacology. 36:527-536
We have studied the metabolism of VP-16-213 (etoposide, VP-16), an antitumor agent, by mouse liver microsomes to reactive intermediates and the subsequent covalent binding to microsomal proteins. This metabolism was shown to involve the O-demethylati
Publikováno v:
Chemischer Informationsdienst. 3