Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Josef Moravek"'
Autor:
Neelakandha S. Mani, Sudip Basu, Josef Moravek, Laurent Gomez, Jiejun Wu, J. Guy Breitenbucher
Publikováno v:
Tetrahedron Letters. 51:1110-1113
Attempts to prepare JNJ 26273364, a highly functionalized pyrazole-based CCK1 receptor antagonist, using a carboxylation reaction led to a series of unexpected results. This work demonstrated the unique reactivity and stability of the highly function
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 43:1119-1125
N-t-Butyl-α-phenylnitrone-α-14C was prepared from benzoic-α-14C acid via benzyl alcohol in 40 –55% yield (sp. activity: 30 mCi/mmol). α-(4-Pyridyl-1-oxide)-N-t-butylnitrone-α-14C arrived from Ba 14CO3 via carboxylation of 4-bromopyridine in 7
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 43:1107-1111
5,5-Dimethyl-1-pyrroline-N-oxide-2-14C arrived via coupling of 2-nitropropane with labelled acrylate instead of acrolein. The new alternate step is safer, more convenient and efficient for 14C-labelling. The radioactive spin trap has a sp. activity o
Autor:
Alessandra Eleuteri, Janis Wright, Raymond F. Schinazi, Selwyn J. Hurwitz, Li Ma, Josef Moravek
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 19(3)
The cellular pharmacology of the D- and L-enantiomers of beta-5-o-carboranyl-2'-deoxyuridine (CDU), compounds designed for boron neutron capture therapy (BNCT), were studied using human CEM lymphoblast and U-251 glioblastoma cells, at a physiological
Publikováno v:
Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis. 5:33-35
We investigated the pharmacokinetics of non-metabolized cefotaxime in 10 patients undergoing CAPD. The elimination half-life after IV administration of I g cefotaxime was 3.1 ± 1.3 hr, i.e. two to three times longer than in individuals with normal r
Publikováno v:
Peritoneal Dialysis International; January 1985, Vol. 5 Issue: 1 p33-35, 3p