Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Josef Loidl"'
Autor:
Jennifer F. Pinello, Josef Loidl, Ethan S. Seltzer, Donna Cassidy-Hanley, Daniel Kolbin, Anhar Abdelatif, Félix A. Rey, Rocky An, Nicole J. Newberger, Yelena Bisharyan, Hayk Papoyan, Haewon Byun, Hector C. Aguilar, Alex L. Lai, Jack H. Freed, Timothy Maugel, Eric S. Cole, Theodore G. Clark
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110146- (2024)
Summary: The ancestral gamete fusion protein, HAP2/GCS1, plays an essential role in fertilization in a broad range of taxa. To identify factors that may regulate HAP2/GCS1 activity, we screened mutants of the ciliate Tetrahymena thermophila for behav
Externí odkaz:
https://doaj.org/article/a7c03bf87ffd45e5b893e26b9f8d81af
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0263691 (2022)
Meiotic DNA double-strand breaks produce reciprocally exchanged DNA strands, which mature into chiasmata that hold homologous chromosomes together as bivalents. These bivalents are subsequently separated in the first meiotic division. In a mutant lac
Externí odkaz:
https://doaj.org/article/8b6f044b37a945e79de1bf310df742fe
Autor:
Josef Loidl
Publikováno v:
PLoS Genetics, Vol 17, Iss 7, p e1009627 (2021)
The presence of meiosis, which is a conserved component of sexual reproduction, across organisms from all eukaryotic kingdoms, strongly argues that sex is a primordial feature of eukaryotes. However, extant meiotic structures and processes can vary c
Externí odkaz:
https://doaj.org/article/c335d7b140e64ada9d441c95f752e09b
Publikováno v:
iScience, Vol 23, Iss 1, Pp - (2020)
Summary: During sexual reproduction in the ciliate, Tetrahymena thermophila, cells of complementary mating type pair (“conjugate”) undergo simultaneous meiosis and fertilize each other. In both mating partners only one of the four meiotic product
Externí odkaz:
https://doaj.org/article/dacdae1829da402097bc36cc3636fc73
Autor:
Miao Tian, Josef Loidl
Publikováno v:
PLoS Genetics, Vol 15, Iss 12, p e1008514 (2019)
Recombinational repair of meiotic DNA double-strand breaks (DSBs) uses the homologous chromosome as a template, although the sister chromatid offers itself as a spatially more convenient substrate. In many organisms, this choice is reinforced by the
Externí odkaz:
https://doaj.org/article/c8fced10488a4d95acc7dd5b8e9ef6fd
Autor:
Takahiko Akematsu, Yasuhiro Fukuda, Jyoti Garg, Jeffrey S Fillingham, Ronald E Pearlman, Josef Loidl
Publikováno v:
eLife, Vol 6 (2017)
Based on observations of markers for DNA lesions, such as phosphorylated histone H2AX (γH2AX) and open DNA ends, it has been suggested that post-meiotic DNA double-strand breaks (PM-DSBs) enable chromatin remodeling during animal spermiogenesis. How
Externí odkaz:
https://doaj.org/article/a4c713a69255436faa25eb014dc3f472
Publikováno v:
PLoS Genetics, Vol 9, Iss 3, p e1003418 (2013)
The cohesion of sister chromatids in the interval between chromosome replication and anaphase is important for preventing the precocious separation, and hence nondisjunction, of chromatids. Cohesion is accomplished by a ring-shaped protein complex, c
Externí odkaz:
https://doaj.org/article/d82b5f491ba24ad2a3b825cc3e05edb5
Publikováno v:
PLoS Genetics, Vol 7, Iss 3, p e1001359 (2011)
Repair of programmed DNA double-strand breaks (DSBs) by meiotic recombination relies on the generation of flanking 3' single-stranded DNA overhangs and their interaction with a homologous double-stranded DNA template. In various common model organism
Externí odkaz:
https://doaj.org/article/3ba28fa1aa31458b97e1061f2bd5673f
Autor:
Antoine Baudrimont, Alexandra Penkner, Alexander Woglar, Yasmine M Mamnun, Margot Hulek, Cathrin Struck, Ralf Schnabel, Josef Loidl, Verena Jantsch
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24799 (2011)
The cohesin complex is required for the cohesion of sister chromatids and for correct segregation during mitosis and meiosis. Crossover recombination, together with cohesion, is essential for the disjunction of homologous chromosomes during the first
Externí odkaz:
https://doaj.org/article/87538796aa384083a94e6747e481cb12
A specialized condensin complex participates in somatic nuclear maturation inTetrahymena thermophila
Publikováno v:
Molecular Biology of the Cell. 30:1326-1338
Condensins are highly conserved proteins that are important for chromosome maintenance in nearly all forms of life. Although many organisms employ two forms of the condensin complex, the condensin genes in Tetrahymena have expanded even further. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcb17b29dd2bf3b2843b766ac6138fc9
https://doi.org/10.1091/mbc.e18-08-0487
https://doi.org/10.1091/mbc.e18-08-0487